Skip to Main content Skip to Navigation
Journal articles

Novel non-carboxylic acid retinoids: 1,2,4-oxadiazol-5-one derivatives.

Abstract : We have successfully obtained 1,2,4-oxadiazol-5-one bioisoteres of Am580 or Tazarotene-like retinoids. In particular compound 4 displays an EC(50) of 26nM on RAR-beta.
Document type :
Journal articles
Complete list of metadatas

Cited literature [4 references]  Display  Hide  Download

https://www.hal.inserm.fr/inserm-00360276
Contributor : Rebecca Deprez-Poulain <>
Submitted on : Tuesday, February 10, 2009 - 6:13:01 PM
Last modification on : Friday, July 17, 2020 - 10:54:05 AM
Long-term archiving on: : Tuesday, June 8, 2010 - 8:39:59 PM

File

manuscript_charton_revised.pdf
Files produced by the author(s)

Identifiers

Collections

Citation

Julie Charton, Rebecca Deprez-Poulain, Nathalie Hennuyer, Anne Tailleux, Bart Staels, et al.. Novel non-carboxylic acid retinoids: 1,2,4-oxadiazol-5-one derivatives.. Bioorganic and Medicinal Chemistry Letters, Elsevier, 2009, 19 (2), pp.489-92. ⟨10.1016/j.bmcl.2008.11.040⟩. ⟨inserm-00360276⟩

Share

Metrics

Record views

291

Files downloads

595