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Structure of full-length PPARgamma-RXRalpha: a snapshot of a functional complex?

Abstract : The first crystal structure of a full-length nuclear receptor complex on DNA reveals an interdomain contact between the ligand- and DNA-binding domains of subunits and illuminates the role of the 5' extension of the binding site in polarity of positioning. These findings have possible functional implications.
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https://www.hal.inserm.fr/inserm-00357462
Contributor : Maité Peney <>
Submitted on : Friday, January 30, 2009 - 2:22:25 PM
Last modification on : Thursday, April 23, 2020 - 2:26:26 PM

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Dino Moras. Structure of full-length PPARgamma-RXRalpha: a snapshot of a functional complex?. Cell Metab, 2009, 9 (1), pp.8-10. ⟨10.1016/j.cmet.2008.12.010⟩. ⟨inserm-00357462⟩

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