Specialization of the general transcriptional machinery in male germ cells. - Archive ouverte HAL Access content directly
Journal Articles Cell Cycle Year : 2008

Specialization of the general transcriptional machinery in male germ cells.

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Abstract

In adult animals, spermatogenesis involves a continuous differentiation of the spermatogonial stem and progenitor cell population into mature sperm. A unique aspect of this developmental process is the germ cell-specific expression and function of paralogues of components of the general transcription machinery, notably subunits of TFIID. Genetic and biochemical studies show that these paralogues play critical, but mechanistically distinct roles in Drosophila and mouse spermatogenesis.
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Dates and versions

inserm-00350905 , version 1 (07-01-2009)

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  • HAL Id : inserm-00350905 , version 1
  • PUBMED : 19001848

Cite

Ullas Kolthur-Seetharam, Igor Martianov, Irwin Davidson. Specialization of the general transcriptional machinery in male germ cells.. Cell Cycle, 2008, 7 (22), pp.3493-8. ⟨inserm-00350905⟩
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