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From cochlear cell death pathways to new pharmacological therapies.

Abstract : Ototoxic drugs, intense sound or age-related hearing loss recruit most of the apoptotic pathways, but also several additional enzymatic pathways which eventually result in cell death. Here, we discuss therapeutic strategies based on the inhibition of regulators or executors of apoptotic cell death pathways and on the use of antioxidants.
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Journal articles
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Contributor : Christian Hamel <>
Submitted on : Wednesday, December 31, 2008 - 11:40:34 AM
Last modification on : Wednesday, June 23, 2021 - 10:20:49 AM


  • HAL Id : inserm-00349485, version 1
  • PUBMED : 18782053



Jing Wang, Jean-Luc Puel. From cochlear cell death pathways to new pharmacological therapies.. Mini Reviews in Medicinal Chemistry / Mini-Reviews in Medicinal Chemistry, 2008, 8 (10), pp.1006-19. ⟨inserm-00349485⟩



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