Conditioning on Certain Random Events Associated with Statistical Variability in PK/PD, Journal of Pharmacokinetics and Pharmacodynamics, vol.92, issue.46, pp.213-243, 2005. ,
DOI : 10.1007/s10928-005-0090-7
Controlling the false discovery rate: a practical and powerful approach to multiple testing, J Roy Stat Soc B Met, vol.57, pp.289-300, 1995. ,
Characterization of the humanMDR1 gene, The AAPS Journal, vol.7, issue.1, pp.1-5, 2005. ,
DOI : 10.1208/aapsj070101
Model selection and Akaike's Information Criterion (AIC): The general theory and its analytical extensions, Psychometrika, vol.10, issue.2, pp.345-370, 1987. ,
DOI : 10.1007/BF02294361
Population pharmacokinetic analysis of indinavir in HIV-infected patient treated with a stable antiretroviral therapy, Fundamental and Clinical Pharmacology, vol.40, issue.3, pp.373-83, 2005. ,
DOI : 10.1097/00002030-200305230-00007
Model Selection and Multimodel. A practical Information-Theoric approach, 2002. ,
EVALUATION OF TESTS BASED ON INDIVIDUAL VERSUS POPULATION MODELING TO COMPARE DISSOLUTION CURVES, Journal of Biopharmaceutical Statistics, vol.11, issue.3, pp.107-123, 2001. ,
DOI : 10.1081/BIP-100107652
Population Pharmacokinetics of Indinavir in Patients Infected with Human Immunodeficiency Virus, Antimicrobial Agents and Chemotherapy, vol.48, issue.9, pp.3226-3258, 2004. ,
DOI : 10.1128/AAC.48.9.3226-3232.2004
Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetics study, The Lancet, vol.359, issue.9300, pp.30-36, 2002. ,
DOI : 10.1016/S0140-6736(02)07276-8
Pharmacokinetic and Pharmacodynamic Data Analysis: Concepts and Applications, 1999. ,
A comparison of estimation methods in nonlinear mixed effects models using a blind analysis, PAGE, vol.14, 2005. ,
High Variability of Indinavir and Nelfinavir Pharmacokinetics in HIV-Infected Patients with a Sustained Virological Response on Highly Active Antiretroviral Therapy, Clinical Pharmacokinetics, vol.30, issue.12, pp.1267-78, 2005. ,
DOI : 10.2165/00003088-200544120-00005
Association of CYP2C8, CYP3A4, CYP3A5, and ABCB1 Polymorphisms with the Pharmacokinetics of Paclitaxel, CYP3A4, CYP3A5, and ABCB1 polymorphisms with the pharmacokinetics of paclitaxel, pp.8097-8104, 2005. ,
DOI : 10.1158/1078-0432.CCR-05-1152
Haplotypes of variants in the UDP-glucuronosyltransferase1A9 and 1A1 genes, Pharmacogenetics and Genomics, vol.15, issue.5, pp.295-301, 2005. ,
DOI : 10.1097/01213011-200505000-00004
Population pharmacokinetics of indinavir alone and in combination with ritonavir in HIV-1-infected patients, British Journal of Clinical Pharmacology, vol.24, issue.3, pp.276-86, 2005. ,
DOI : 10.1067/mcp.2002.121424
Population pharmacokinetic modelling of darifenacin and its hydroxylated metabolite using pooled data, incorporating saturable first-pass metabolism, CYP2D6 genotype and formulation-dependent bioavailability, British Journal of Clinical Pharmacology, vol.56, issue.6, pp.639-652, 2003. ,
DOI : 10.1046/j.1365-2125.2003.01967.x
Pharmacogenomics The search for individualized therapy, 2002. ,
Sample size tables for clinical studies, 1997. ,
DOI : 10.1002/9781444300710
CYP2C19 polymorphism effect on phenobarbitone, European Journal of Clinical Pharmacology, vol.55, issue.11-12, pp.821-825, 2000. ,
DOI : 10.1007/s002280050703
Polymorphisms in human MDR1 (P-glycoprotein): recent advances and clinical relevance, Clinical Pharmacology & Therapeutics, vol.75, issue.1, pp.13-33, 2003. ,
DOI : 10.1016/j.clpt.2003.09.012
Co-administration of cyclosporine A enables oral therapy with paclitaxel, Clin Cancer Res, vol.5, pp.3379-84, 1999. ,
Prospective trial to evaluate how therapeutic drug monitoring of protease inhibitors increases virologic success and tolerance of HAART (COPHAR 2 - ANRS 111 trial, 12th Conference on Retroviruses and Opportunistic Infections, 2005. ,
CYP3A5 Polymorphism and the Ethnic Differences in Cyclosporine Pharmacokinetics in Healthy Subjects 1, Therapeutic Drug Monitoring, vol.26, issue.5, pp.524-528, 2004. ,
DOI : 10.1097/00007691-200410000-00010
Evaluation by simulation of tests based on non-linear mixed-effects models in pharmacokinetic interaction and bioequivalence cross-over trials, Statistics in Medicine, vol.83, issue.10, 2005. ,
DOI : 10.1002/sim.2047
Bayesian Model Selection in Social Research (with discussion), Sociol Methodol, pp.111-195, 1995. ,
Design in nonlinear mixed effects models: Optimization using the Fedorov???Wynn algorithm and power of the Wald test for binary covariates, Statistics in Medicine, vol.39, issue.28, 2007. ,
DOI : 10.1002/sim.2910
URL : https://hal.archives-ouvertes.fr/hal-00263513
Optimization of Individual and Population Designs Using Splus, Journal of Pharmacokinetics and Pharmacodynamics, vol.30, issue.6, pp.417-460, 2003. ,
DOI : 10.1023/B:JOPA.0000013000.59346.9a
MDR1 Genotype-Related Pharmacokinetics and Pharmacodynamics, Biological & Pharmaceutical Bulletin, vol.25, issue.11, pp.1391-1400, 2002. ,
DOI : 10.1248/bpb.25.1391
The SAEM algorithm for group comparison test in longitudinal data analysis based in nonlinear mixed-effects model, 2007. ,
Estimating the Dimension of a Model, The Annals of Statistics, vol.6, issue.2, pp.461-464, 1978. ,
DOI : 10.1214/aos/1176344136
NONMEM Version 5.1. San Francisco University of California, 1998. ,