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A prospective study of hormonal treatment and anxiety disorders in community-dwelling elderly women (the Esprit Study).

Abstract : BACKGROUND: The impact of hormone therapy use on late-life anxiety disorder in elderly women has not been evaluated. METHODS: Anxiety disorders were evaluated in 838 community-dwelling postmenopausal women aged 65 years and over, randomly recruited from electoral rolls. Anxiety disorders were assessed using a standardized psychiatric examination based on DSM-IV criteria, at baseline and as part of the 2- and 4-year follow-up. RESULTS: Multivariate logistic regression analyses adjusted for socio-demographic variables, measures of physical health and cognitive impairment, as well as current depressive symptomatology indicated no significant association between hormone therapy and anxiety disorders at baseline or after the 4-year follow-up period, regardless of type of treatment. Compared to women who have never taken hormonal therapy, no significant difference was observed for women taking continuously hormone therapy over the follow-up or those who stopped their treatment. CONCLUSIONS: The use of hormone therapy was not associated with improved anxiety symptomatology in elderly postmenopausal women.
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https://www.hal.inserm.fr/inserm-00337040
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Submitted on : Wednesday, November 5, 2008 - 5:16:42 PM
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Jacqueline Scali, Joanne Ryan, Isabelle Carrière, Karen Ritchie, Marie-Laure Ancelin. A prospective study of hormonal treatment and anxiety disorders in community-dwelling elderly women (the Esprit Study).. Journal of Affective Disorders, Elsevier, 2009, 115 (1-2), pp.274-9. ⟨10.1016/j.jad.2008.09.007⟩. ⟨inserm-00337040⟩

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