Abstract : We show in this review that there is a continuum between the chicken B-cell system classified as the first GALT model described and the human B-cell system. We propose that humans have conserved for one B-cell subpopulation, the marginal zone B-cell subset in charge of T-independent responses, the strategies of diversification used by GALT species to generate their pre-immune repertoire.
https://www.hal.inserm.fr/inserm-00337036
Contributor : Sandra Weller <>
Submitted on : Wednesday, November 5, 2008 - 5:06:21 PM Last modification on : Friday, March 27, 2020 - 2:17:25 AM Long-term archiving on: : Tuesday, October 9, 2012 - 3:01:52 PM
Jean-Claude Weill, Sandra Weller, Claude-Agnès Reynaud. A bird's eye view on human B cells.. Seminars in Immunology, Elsevier, 2004, 16 (4), pp.277-81. ⟨10.1016/j.smim.2004.08.007⟩. ⟨inserm-00337036⟩