Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA, Science, vol.245, issue.4922, pp.1066-1073, 1989. ,
DOI : 10.1126/science.2475911
How do cystic fibrosis transmembrane conductance regulator mutations produce lung disease?, Current Opinion in Pulmonary Medicine, vol.1, issue.6, pp.435-443, 1995. ,
DOI : 10.1097/00063198-199511000-00002
Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel, Cell, vol.66, issue.5, pp.1027-1036, 1991. ,
DOI : 10.1016/0092-8674(91)90446-6
Submucosal glands are the predominant site of CFTR expression in the human bronchus, Nature Genetics, vol.89, issue.3, pp.240-248, 1992. ,
DOI : 10.1038/ng0892-321
Characterization of Wild-Type and ??F508 Cystic Fibrosis Transmembrane Regulator in Human Respiratory Epithelia, Molecular Biology of the Cell, vol.16, issue.5, pp.2154-2167, 2005. ,
DOI : 10.1091/mbc.E04-11-1010
Acinar origin of CFTR-dependent airway submucosal gland fluid secretion, AJP: Lung Cellular and Molecular Physiology, vol.292, issue.1, pp.304-311, 2007. ,
DOI : 10.1152/ajplung.00286.2006
An antibody against a cftr-derived synthetic peptide, incorporated into living submandibular cells, inhibits beta-adrenergic stimulation of mucin secretion, Biochemical and Biophysical Research Communications, vol.188, issue.3, pp.1146-1152, 1992. ,
DOI : 10.1016/0006-291X(92)91351-P
Multiple intracellular pathways for regulation of chloride secretion in cultured pig tracheal submucosal gland cells, European Respiratory Journal, vol.13, issue.3, pp.571-576, 1999. ,
DOI : 10.1183/09031936.99.13357199
Effects of ??-agonists on airway epithelial cells, Journal of Allergy and Clinical Immunology, vol.110, issue.6, pp.275-281, 2002. ,
DOI : 10.1067/mai.2002.129412
Autoradiographic Visualization of Beta- Adrenoceptor Subtypes in Human Lung, Am Rev Respir Dis, vol.132, pp.541-547, 1985. ,
Stimulation of beta 2-Adrenergic Receptor Increases Cystic Fibrosis Transmembrane Conductance Regulator Expression in Human Airway Epithelial Cells through a cAMP/Protein Kinase A-independent Pathway, Journal of Biological Chemistry, vol.278, issue.19, pp.17320-17327, 2003. ,
DOI : 10.1074/jbc.M212227200
URL : https://hal.archives-ouvertes.fr/inserm-00149003
A macromolecular complex of ??2 adrenergic receptor, CFTR, and ezrin/radixin/moesin-binding phosphoprotein 50 is regulated by PKA, Proceedings of the National Academy of Sciences, vol.100, issue.1, pp.342-346, 2003. ,
DOI : 10.1073/pnas.0135434100
Activation of an Apical Cl-Conductance by Ca2+ Ionophores in Cystic Fibrosis Airway Epithelia, Am J Physiol, vol.256, pp.226-233, 1989. ,
Cystic Fibrosis and Beta-Adrenergic Response of Airway Epithelial Cell Cultures, Am J Physiol, vol.251, pp.818-822, 1986. ,
What???s new in cystic fibrosis? From treating symptoms to correction of the basic defect, European Journal of Pediatrics, vol.125, issue.suppl B, 2008. ,
DOI : 10.1007/s00431-008-0693-2
A Cystic Fibrosis Tracheal Gland Cell Line, CF-KM4, American Journal of Respiratory Cell and Molecular Biology, vol.20, issue.4, pp.684-691, 1999. ,
DOI : 10.1165/ajrcmb.20.4.3341
A transformed human tracheal gland cell line, MM-39, that retains serous secretory functions., American Journal of Respiratory Cell and Molecular Biology, vol.15, issue.4, pp.520-528, 1996. ,
DOI : 10.1165/ajrcmb.15.4.8879186
-adrenoceptor-mediated responses in human lung mast cells, British Journal of Pharmacology, vol.247, issue.4, pp.711-718, 1998. ,
DOI : 10.1038/sj.bjp.0701897
URL : https://hal.archives-ouvertes.fr/hal-00618485
A small molecule CFTR inhibitor produces cystic fibrosis-like submucosal gland fluid secretions in normal airways, The FASEB Journal, vol.18, pp.875-877, 2004. ,
DOI : 10.1096/fj.03-1248fje
Analysis of image sequences in fluorescence videomicroscopy of stationary objects, Cytometry, vol.31, issue.3, pp.217-228, 1998. ,
DOI : 10.1002/(SICI)1097-0320(19980301)31:3<217::AID-CYTO9>3.0.CO;2-H
Ion Composition and Rheology of Airway Liquid from Cystic Fibrosis Fetal Tracheal Xenografts, American Journal of Respiratory Cell and Molecular Biology, vol.20, issue.4, pp.605-611, 1999. ,
DOI : 10.1165/ajrcmb.20.4.3264
The Determination of Wet Weight Concentrations of Elements in Freeze- Dried Cryosections From Biological Cells, Scan Electron Microsc, pp.713-724, 1986. ,
Effects of Cadmium on Electrolyte Ions in Cultured Rat Hepatocytes Studied by X-Ray Microanalysis of Cryosections, Toxicology and Applied Pharmacology, vol.144, issue.1, pp.70-76, 1997. ,
DOI : 10.1006/taap.1996.8094
Isolation of Stable Pancreatic Zymogen Granules, Am J Physiol, vol.246, pp.411-418, 1984. ,
Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive, Nature, vol.358, issue.6389, pp.761-764, 1992. ,
DOI : 10.1038/358761a0
Fluid transport across cultures of human tracheal glands is altered in cystic fibrosis, The Journal of Physiology, vol.270, issue.3, pp.637-647, 1997. ,
DOI : 10.1111/j.1469-7793.1997.637bm.x
Conductances, The Journal of General Physiology, vol.279, issue.3, pp.407-418, 2002. ,
DOI : 10.1007/s004240050586
Chloride transporting capability of Calu-3 epithelia following persistent knockdown of the cystic fibrosis transmembrane conductance regulator, CFTR, British Journal of Pharmacology, vol.438, issue.8, pp.1055-1065, 2007. ,
DOI : 10.1038/sj.bjp.0707175
-Adrenergic Receptor Agonist, American Journal of Respiratory Cell and Molecular Biology, vol.30, issue.5, pp.605-612, 2004. ,
DOI : 10.1165/rcmb.2003-0056OC
URL : https://hal.archives-ouvertes.fr/hal-00809316
Sustained Activation of a G Protein-Coupled Receptor Via "Anchored" Agonist Binding. Molecular Localization of the Salmeterol Exosite Within the 2-Adrenergic Receptor, J Biol Chem, vol.271, pp.24029-24035, 1996. ,
-Adrenergic Receptor Phosphorylation and Internalization, American Journal of Respiratory Cell and Molecular Biology, vol.36, issue.2, pp.254-261, 2007. ,
DOI : 10.1165/rcmb.2006-0158OC
URL : https://hal.archives-ouvertes.fr/hal-00506463
-adrenoceptor, British Journal of Pharmacology, vol.269, issue.4, pp.701-711, 1998. ,
DOI : 10.1038/sj.bjp.0701658
Calcium-pump inhibitors induce functional surface expression of ??F508-CFTR protein in cystic fibrosis epithelial cells, Nature Medicine, vol.262, issue.5, pp.485-492, 2002. ,
DOI : 10.1083/jcb.121.2.283
Correctors promote folding of the CFTR in the endoplasmic reticulum, Biochemical Journal, vol.413, issue.1, pp.29-36, 2008. ,
DOI : 10.1042/BJ20071690
Enhanced cell-surface stability of rescued DeltaF508 cystic fibrosis transmembrane conductance regulator (CFTR) by pharmacological chaperones ,
airway epithelial monolayers, The Journal of Physiology, vol.67, issue.7, pp.601-615, 2005. ,
DOI : 10.1113/jphysiol.2005.096669
Ion composition of airway surface liquid of patients with cystic fibrosis as compared with normal and disease-control subjects., Journal of Clinical Investigation, vol.100, issue.10, pp.2588-2595, 1997. ,
DOI : 10.1172/JCI119802
X-Ray Microanalysis of Airway Surface Liquid Collected in Cystic Fibrosis Mice, Am J Physiol Lung Cell Mol Physiol, vol.281, pp.309-313, 2001. ,
URL : https://hal.archives-ouvertes.fr/inserm-00152532
Ion channels in secretory granules of the pancreas and their role in exocytosis and release of secretory proteins, AJP: Cell Physiology, vol.283, issue.3, pp.651-672, 2002. ,
DOI : 10.1152/ajpcell.00600.2001
AQPs and Control of Vesicle Volume in Secretory Cells, Journal of Membrane Biology, vol.84, issue.2, pp.155-159, 2006. ,
DOI : 10.1007/s00232-005-0853-5
Mucous granule exocytosis and CFTR expression in gallbladder epithelium, Glycobiology, vol.10, issue.2, pp.149-157, 2000. ,
DOI : 10.1093/glycob/10.2.149
Autonomic Regulation of Viscoelasticity of Cat Tracheal Gland Secretions, J Appl Physiol, vol.56, pp.426-430, 1984. ,
Mucin Granule Intraluminal Organization, American Journal of Respiratory Cell and Molecular Biology, vol.36, issue.2, pp.183-190, 2007. ,
DOI : 10.1165/rcmb.2006-0291TR
Localization of the Cystic Fibrosis Transmembrane Conductance Regulator in Airway Secretory Glands, Eur Respir J, vol.6, pp.169-176, 1993. ,
Absence of CFTR is associated with pleiotropic effects on mucins in mouse gallbladder epithelial cells, AJP: Gastrointestinal and Liver Physiology, vol.291, issue.6, pp.1148-1154, 2006. ,
DOI : 10.1152/ajpgi.00547.2005
Effectiveness and tolerability of high-dose salmeterol in cystic fibrosis, Pediatric Pulmonology, vol.89, issue.4, pp.287-296, 2002. ,
DOI : 10.1002/ppul.10162