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[Non-solid and part-solid pulmonary nodules on CT scanning]

Abstract : INTRODUCTION: The entities of non-solid and part-solid pulmonary nodules on CT scan have been recently described.STATE OF ART: Nonsolid and part-solid pulmonary nodules account for between 2.9 and 19% of all pulmonary nodules detected in high-risk patients included in CT screening series for lung cancer. Radio-pathological correlations have shown that the aetiology could be either benign (chronic pneumonia, atypical adenomatous hyperplasia, localized fibrosis) or malignant (broncholoalveolar cell carcinoma, adenocarcinoma, more rarely metastasis). Part-solid or non-solid nodules are more likely to be malignant than solid ones. The doubling time of non-solid nodules can be longer than part-solid ones and even longer than the doubling time of solid nodules. Patient prognosis is related to the proportion of the ground glass component.PERSPECTIVE: The management of these nodules requires prolonged surveillance of nodules less than 10mm in diameter and surgical excision of nodules greater than 10mm persisting on scans between 1 to 3 months after they have been discovered and anti-inflammatory and anti-infectious therapy has been administered.CONCLUSIONS: Nonsolid and part-solid pulmonary nodules found on CT scan warrant a specific diagnostic workup.
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https://www.hal.inserm.fr/inserm-00332688
Contributor : Aurélien Vesin <>
Submitted on : Tuesday, October 21, 2008 - 3:33:54 PM
Last modification on : Friday, November 6, 2020 - 4:04:39 AM

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  • HAL Id : inserm-00332688, version 1
  • PUBMED : 18216747

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Gilbert Ferretti, Laure Félix, Géraldine Serra-Tosio, Christian Brambilla, Denis Moro-Sibilot, et al.. [Non-solid and part-solid pulmonary nodules on CT scanning]. Revue des Maladies Respiratoires, Elsevier Masson, 2007, 24 (10), pp.1265-76. ⟨inserm-00332688⟩

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