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Whole body small animal examination with a diffuse optical tomography instrument

Anne Koenig 1, * Lionel Hervé 1 Anabela da Silva 1 Jean-Marc Dinten 1 Jérôme Boutet 1 Michel Berger 1 Isabelle Texier 1 Philippe Peltié 1 Philippe Rizo 1 Veronique Josserand 2 Jean-Luc Coll 3 
* Corresponding author
1 CEA-LETI - Commissariat à l'énergie atomique et aux énergies alternatives - Laboratoire d'Electronique et de Technologie de l'Information
2 INSERM U823 - Institut d'oncologie/développement Albert Bonniot de Grenoble
3 INSERM U823, équipe 5 (cibles diagnostiques ou thérapeutiques et vectorisation de drogues dans le cancer du poumon)
INSERM U823 - Institut d'oncologie/développement Albert Bonniot de Grenoble
Abstract : We developed a fluorescent diffuse optical tomography instrument in our laboratory to study in vivo tumour growth without any stress or damage for the animal. By taking into account optical heterogeneities, the reconstruction algorithm allows whole body small animal examination. Experimental results obtained with this system on phantoms and on mice deep lung tumours examination are presented in this paper.
Keywords : Optical tomography 3D Reconstruction Fluorescence In vivo examination
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https://www.hal.inserm.fr/inserm-00331928
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Submitted on : Monday, October 20, 2008 - 10:15:33 AM
Last modification on : Friday, November 6, 2020 - 11:18:15 AM
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  • HAL Id : inserm-00331928, version 1

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Anne Koenig, Lionel Hervé, Anabela da Silva, Jean-Marc Dinten, Jérôme Boutet, et al.. Whole body small animal examination with a diffuse optical tomography instrument. Nuclear Instruments and Methods in Physics Research, Elsevier, 2007, 571, pp.56-59. ⟨inserm-00331928⟩

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