Skip to Main content Skip to Navigation
Journal articles

Cytoreductive partial nephrectomy does not undermine cancer control in metastatic renal cell carcinoma: a population-based study.

Abstract : OBJECTIVES: We examined the population-based rates of cancer-specific survival in patients with metastatic renal cell carcinoma (MRCC) treated with either partial (PN) or radical cytoreductive nephrectomy (RN). METHODS: Patients diagnosed with MRCC and treated with either PN or RN were identified within nine SEER cancer registries. Matched and unmatched Kaplan-Meier survival analyses, as well as multivariable Cox regression models compared the effect of RN (n = 1997, 97.8%) vs. PN (n = 46, 2.2%) on cancer-specific survival (CSS). Covariates consisted of age, gender, community type (rural vs urban), race, Surveillance, Epidemiology, and End Results (SEER) registry, tumor size and year of diagnosis. RESULTS: In multivariable unmatched Cox regression analyses, no statistically significantly difference was found in CSS between the two groups (hazard ratio [HR] 1.40, P = .16). Similarly, no difference in CSS was found in the matched analyses (HR 1.35, log rank P = .34). CONCLUSION: Cytoreductive PN does not appear to undermine survival in patients with MRCC.
Complete list of metadata

https://www.hal.inserm.fr/inserm-00325530
Contributor : Hervé De Villemeur Connect in order to contact the contributor
Submitted on : Monday, September 29, 2008 - 3:34:56 PM
Last modification on : Wednesday, March 30, 2022 - 2:35:15 PM

Links full text

Identifiers

Citation

Umberto Capitanio, Laurent Zini, Paul Perrotte, Shahrokh F. Shariat, Claudio Jeldres, et al.. Cytoreductive partial nephrectomy does not undermine cancer control in metastatic renal cell carcinoma: a population-based study.. Urology, Elsevier, 2008, 72 (5), pp.1090-5. ⟨10.1016/j.urology.2008.06.059⟩. ⟨inserm-00325530⟩

Share

Metrics

Record views

83