B. Brunekreef and S. Holgate, Air pollution and health, The Lancet, vol.360, issue.9341, pp.1233-1242, 2002.
DOI : 10.1016/S0140-6736(02)11274-8

C. Pope and D. Dockery, Health Effects of Fine Particulate Air Pollution: Lines that Connect, Journal of the Air & Waste Management Association, vol.56, issue.6, pp.709-742, 2006.
DOI : 10.1080/10473289.2006.10464485

N. Künzli and I. Tager, Air pollution: from lung to heart, Swiss Med Wkly, vol.135, pp.697-702, 2005.

H. Boezen, J. Vonk, and S. Van-der-zee, Susceptibility to air pollution in elderly males and females, European Respiratory Journal, vol.25, issue.6, pp.1018-1024, 2005.
DOI : 10.1183/09031936.05.00076104

H. Desqueyroux, J. Pujet, and M. Prosper, Short-Term Effects of Low-Level Air Pollution on Respiratory Health of Adults Suffering from Moderate to Severe Asthma, Environmental Research, vol.89, issue.1, pp.29-37, 2002.
DOI : 10.1006/enrs.2002.4357

J. Gent, E. Triche, and T. Holford, Association of Low-Level Ozone and Fine Particles With Respiratory Symptoms in Children With Asthma, JAMA, vol.290, issue.14, pp.1859-1867, 2003.
DOI : 10.1001/jama.290.14.1859

T. Hiltermann, J. Stolk, and S. Van-der-zee, Asthma severity and susceptibility to air pollution, Eur Respir J, vol.11, pp.686-693, 1998.

L. Moual, N. Siroux, V. Pin, and I. , Asthma Severity and Exposure to Occupational Asthmogens, American Journal of Respiratory and Critical Care Medicine, vol.172, issue.4, pp.440-445, 2005.
DOI : 10.1164/rccm.200501-111OC

URL : https://hal.archives-ouvertes.fr/inserm-00308790

J. Pekkanen, J. Sunyer, and J. Anto, European Community Respiratory Health Study. Operational definitions of asthma in studies on its aetiology, Eur Respir J, vol.2607, issue.9, pp.28-35, 2005.

S. Wenzel, Asthma: defining of the persistent adult phenotypes, The Lancet, vol.368, issue.9537, pp.804-813, 2006.
DOI : 10.1016/S0140-6736(06)69290-8

V. Siroux, I. Pin, and M. Oryszczyn, Relationships of active smoking to asthma and asthma severity in the EGEA study, European Respiratory Journal, vol.15, issue.3, pp.470-477, 2000.
DOI : 10.1034/j.1399-3003.2000.15.08.x

URL : https://hal.archives-ouvertes.fr/inserm-00780296

R. Varraso, V. Siroux, and J. Maccario, Asthma Severity Is Associated with Body Mass Index and Early Menarche in Women, American Journal of Respiratory and Critical Care Medicine, vol.171, issue.4, pp.334-339, 2005.
DOI : 10.1164/rccm.200405-674OC

URL : https://hal.archives-ouvertes.fr/inserm-00331328

F. Kauffmann, M. Dizier, I. Pin, E. Paty, F. Gormand et al., Epidemiological Study of the Genetics and Environment of Asthma, Bronchial Hyperresponsiveness, and Atopy, American Journal of Respiratory and Critical Care Medicine, vol.156, issue.4, pp.123-129, 1997.
DOI : 10.1164/ajrccm.156.4.12tac9

URL : https://hal.archives-ouvertes.fr/hal-00596474

F. Kauffmann, I. Annesi-maesano, and R. Liard, Construction et validation d'un questionnaire en épidémiologie respiratoire. L'exemple du questionnaire de l'Etude Epidémiologique des facteurs Génétiques et Environnementaux de l'Asthme, l'hyperréactivité bronchique et l'atopie (EGEA), Rev Mal Respir, vol.19, pp.323-333, 2002.

I. Pin, V. Siroux, and C. Cans, Familial Resemblance of Asthma Severity in the EGEA* Study, American Journal of Respiratory and Critical Care Medicine, vol.165, issue.2, pp.185-189, 2002.
DOI : 10.1164/ajrccm.165.2.2012019

URL : https://hal.archives-ouvertes.fr/inserm-00780298

V. Siroux, F. Kauffmann, and C. Pison, Caract??re multidimensionnel de la s??v??rit?? de l???asthme dans l???enqu??te EGEA, Revue des Maladies Respiratoires, vol.21, issue.5, pp.917-924, 2004.
DOI : 10.1016/S0761-8425(04)71473-4

N. Jeannée, Cartography of atmospheric pollution at the France national scale for the atlas of air quality monitoring, 2006.

J. Chilès and P. Delfiner, Geostatistics: modelling spatial uncertainty, Wiley Series in Probability and Mathematical Statistics, 1999.
DOI : 10.1002/9781118136188

N. Jeannée, L. Mosqueron, and V. Nedellec, Evaluation de l'exposition des populations à la pollution atmosphérique: méthodologies existantes et application aux PM10 à l'échelle de la France métropolitaine, Pollution Atmosphérique, vol.190, pp.197-209, 2006.

N. Jeannée, V. Nedellec, and S. Bouallala, Geostatistical assessment of long term human exposure to air pollution, geoENV V -Geostatistics for Environmental Applications, pp.161-172, 2004.
DOI : 10.1007/3-540-26535-X_14

S. Kennedy, L. Moual, N. Choudat, and D. , Development of an asthma specific job exposure matrix and its application in the epidemiological study of genetics and environment in asthma (EGEA), Occupational and Environmental Medicine, vol.57, issue.9, pp.635-641, 2000.
DOI : 10.1136/oem.57.9.635

J. Sunyer, C. Spix, and P. Quénel, Urban air pollution and emergency admissions for asthma in four European cities: the APHEA Project, Thorax, vol.52, issue.9, pp.760-765, 1997.
DOI : 10.1136/thx.52.9.760

U. Neuhaus-steinmetz, F. Uffhausen, and U. Herz, Priming of Allergic Immune Responses by Repeated Ozone Exposure in Mice, American Journal of Respiratory Cell and Molecular Biology, vol.23, issue.2, pp.228-233, 2000.
DOI : 10.1165/ajrcmb.23.2.3898

D. Peden, B. Boehlecke, and D. Horstman, Prolonged acute exposure to 0.16 ppm ozone induces eosinophilic airway inflammation in asthmatic subjects with allergies, Journal of Allergy and Clinical Immunology, vol.100, issue.6, pp.802-808, 1997.
DOI : 10.1016/S0091-6749(97)70277-X

M. Oryszczyn, E. Bouzigon, and J. Maccario, Interrelationships of quantitative asthma-related phenotypes in the Epidemiological Study on the Genetics and Environment of Asthma, Bronchial Hyperresponsiveness, and??Atopy, Journal of Allergy and Clinical Immunology, vol.119, issue.1, pp.57-63, 2007.
DOI : 10.1016/j.jaci.2006.09.026

URL : https://hal.archives-ouvertes.fr/inserm-00335814

I. Romieu, M. Ramirez-aguilar, and J. Sienra-monge, GSTM1 and GSTP1 and respiratory health in asthmatic children exposed to ozone, European Respiratory Journal, vol.28, issue.5, pp.953-959, 2006.
DOI : 10.1183/09031936.06.00114905

U. Frey, T. Bordbeck, and A. Majumdar, Risk of severe asthma episodes predicted from fluctuation analysis of airway function, Nature, vol.92, issue.7068, pp.667-670, 2005.
DOI : 10.1038/nature04176

E. Bouzigon, V. Siroux, and M. Dizier, Scores of asthma and asthma severity reveal new regions of linkage in EGEA study families, European Respiratory Journal, vol.30, issue.2, pp.30-253, 2007.
DOI : 10.1183/09031936.00162206

J. Sunyer, J. Pekkanen, and R. Garcia-esteban, Asthma score: predictive ability and risk factors, Allergy, vol.171, issue.2, pp.142-148, 2007.
DOI : 10.1111/j.1398-9995.2006.01184.x

W. Gauderman, Air Pollution and Children ??? An Unhealthy Mix, New England Journal of Medicine, vol.355, issue.1, pp.78-79, 2006.
DOI : 10.1056/NEJMe068096

N. Künzli and B. Tager, Long-Term Health Effects of Particulate and Other Ambient Air Pollution: Research Can Progress Faster If We Want It To, Environmental Health Perspectives, vol.108, issue.10, pp.915-918, 2000.
DOI : 10.1289/ehp.00108915

J. Schildcrout, L. Sheppard, and T. Lumley, Ambient Air Pollution and Asthma Exacerbations in Children: An Eight-City Analysis, American Journal of Epidemiology, vol.164, issue.6, pp.505-517, 2006.
DOI : 10.1093/aje/kwj225

J. Levy, S. Chemerynshki, and J. Sarnat, Ozone Exposure and Mortality, Epidemiology, vol.16, issue.4, pp.458-468, 2005.
DOI : 10.1097/01.ede.0000165820.08301.b3

C. Schweizer, R. Edwards, and L. Bayer-oglesby, Indoor time???microenvironment???activity patterns in seven regions of Europe, Journal of Exposure Science and Environmental Epidemiology, vol.14, issue.2, pp.170-181, 2006.
DOI : 10.1038/sj.jes.7500490

C. Schindler, N. Künzli, and J. Bongard, Short-Term Variation in Air Pollution and in Average Lung Function Among Never-Smokers, American Journal of Respiratory and Critical Care Medicine, vol.163, issue.2, pp.356-361, 2001.
DOI : 10.1164/ajrccm.163.2.9911116

U. S. Epa, Air Quality Criteria for Ozone and Related Photochemical Oxidants (Final), U.S. Environmental Protection Agency, vol.600, p.4