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Journal Articles AIDS Year : 2008

One or two enzyme-linked immunosorbent assay tests on the first serum sample for initial diagnosis of HIV-1 infection?

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Abstract

In France, the first sample for the initial diagnosis of HIV-1 infection must be tested with two antibody assays: one being an enzyme-linked immunosorbent assay. If one is positive, confirmation tests are performed. We evaluated the performance of initial diagnostic strategies based on the use of one versus two enzyme-linked immunosorbent assay tests, either an antigen-antibody test or a simple antibody assay. We found that a single antigen-antibody test was more efficient than a combination of the two tests.

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Dates and versions

inserm-00321930 , version 1 (16-09-2008)

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Dominique Costagliola, Florence Damond, Pierre Palmer, Christine Rouzioux, Francoise Brun-Vézinet. One or two enzyme-linked immunosorbent assay tests on the first serum sample for initial diagnosis of HIV-1 infection?. AIDS, 2008, 22 (15), pp.2042-4. ⟨10.1097/QAD.0b013e328311869f⟩. ⟨inserm-00321930⟩
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