X. Badia, M. Brosa, and J. M. Tellado, Evidence-based medicine, health costs and treatment of intra-abdominal infection, Enferm. Infecc. Microbiol. Clin, vol.17, pp.86-94, 1999.

L. Bahlmann, U. Markert, C. Wirtz, M. Heringlake, W. Eichler et al., Mikrodialyse als Verfahren zur Beurteilung einer intestinalen Hypoxie - ein tierexperimenteller Ansatz. Microdialysis for the Evaluation of Intestinal Hypoxia - an Animal Experiment., Biomedizinische Technik/Biomedical Engineering, vol.48, issue.1-2, pp.27-30, 2003.
DOI : 10.1515/bmte.2003.48.1-2.27

J. M. Bohnen, J. S. Solomkin, E. P. Dellinger, H. S. Bjornson, and C. P. Page, Guidelines for Clinical Care: Anti-infective Agents for Intra-abdominal Infection, Archives of Surgery, vol.127, issue.1, pp.83-89, 1992.
DOI : 10.1001/archsurg.1992.01420010097015

N. V. Christou, P. Turgeon, R. Wassef, O. Rotstein, J. Bohnen et al., Management of Intra-abdominal Infections, Archives of Surgery, vol.131, issue.11, pp.1193-1201, 1996.
DOI : 10.1001/archsurg.1996.01430230075014

A. Giacometti, O. Cirioni, R. Ghiselli, F. Mocchegiani, M. S. Del-prete et al., Potential Therapeutic Role of Cationic Peptides in Three Experimental Models of Septic Shock, Antimicrobial Agents and Chemotherapy, vol.46, issue.7, pp.2132-2136, 2002.
DOI : 10.1128/AAC.46.7.2132-2136.2002

W. C. Hellinger and N. S. Brewer, Carbapenems and Monobactams: Imipenem, Meropenem, and Aztreonam, Mayo Clinic Proceedings, vol.74, issue.4, pp.420-434, 1999.
DOI : 10.4065/74.4.420

J. A. Hopkins, J. C. Lee, and S. E. Wilson, Susceptibility of intraabdominal isolates at operation: a predictor of postoperative infection, Am. Surg, vol.59, pp.791-796, 1993.

K. Jansson, B. Redler, L. Truedsson, A. Magnuson, U. Ungerstedt et al., Postoperative on???line monitoring with intraperitoneal microdialysis is a sensitive clinical method for measuring increased anaerobic metabolism that correlates to the cytokine response, Scandinavian Journal of Gastroenterology, vol.47, issue.8787, pp.434-439, 2004.
DOI : 10.1097/00003246-199805000-00025

C. C. Johnson, J. Baldessarre, and M. E. Levison, Peritonitis: Update on Pathophysiology, Clinical Manifestations, and Management, Clinical Infectious Diseases, vol.24, issue.6, pp.1035-1045, 1997.
DOI : 10.1086/513658

S. Klaus, M. Heringlake, J. Gliemroth, H. P. Bruch, and L. Bahlmann, Intraperitoneal microdialysis for detection of splanchnic metabolic disorders, Langenbeck's Archives of Surgery, vol.387, issue.7-8, pp.276-280, 2002.
DOI : 10.1007/s00423-002-0320-z

S. Klaus, M. Heringlake, J. Gliemroth, H. Pagel, K. Staubach et al., Biochemical tissue monitoring during hypoxia and reoxygenation, Resuscitation, vol.56, issue.3, pp.299-305, 2003.
DOI : 10.1016/S0300-9572(02)00342-8

S. Klaus, C. Wirtz, W. Baumeier, J. Gliemroth, P. Schmucker et al., Continuous biochemical tissue monitoring during acute hypoxia, Anaesthesiol. Reanim, vol.28, pp.104-109, 2003.

U. Korth, H. Krieter, C. Denz, C. Janke, K. Ellinger et al., Intestinal ischaemia during cardiac arrest and resuscitation: comparative analysis of extracellular metabolites by microdialysis, Resuscitation, vol.58, issue.2, pp.209-217, 2003.
DOI : 10.1016/S0300-9572(03)00119-9

P. Liu, M. Muller, and H. Derendorf, Rational dosing of antibiotics: the use of plasma concentrations versus tissue concentrations, International Journal of Antimicrobial Agents, vol.19, issue.4, pp.285-290, 2002.
DOI : 10.1016/S0924-8579(02)00024-9

S. Marchand, M. Chenel, C. Pariat, and W. Couet, Dose ranging pharmacokinetics and brain distribution of norfloxacin using microdialysis in rats, Journal of Pharmaceutical Sciences, vol.92, issue.12, pp.1-9, 2003.
DOI : 10.1002/jps.10504

S. Marchand, C. Dahyot, I. Lamarche, O. Mimoz, and W. Couet, Microdialysis Study of Imipenem Distribution in Skeletal Muscle and Lung Extracellular Fluids of Noninfected Rats, Antimicrobial Agents and Chemotherapy, vol.49, issue.6, pp.2356-2361, 2005.
DOI : 10.1128/AAC.49.6.2356-2361.2005

J. E. Mazuski, R. G. Sawyer, A. B. Nathens, J. T. Dipiro, M. Schein et al., The Surgical Infection Society Guidelines on Antimicrobial Therapy for Intra-Abdominal Infections: An Executive Summary, Surgical Infections, vol.3, issue.3, pp.161-173, 2002.
DOI : 10.1089/109629602761624171

M. Müller, A. De-la-peña, and H. Derendorf, Issues in Pharmacokinetics and Pharmacodynamics of Anti-Infective Agents: Distribution in Tissue, Antimicrobial Agents and Chemotherapy, vol.48, issue.5, pp.1441-1453, 2004.
DOI : 10.1128/AAC.48.5.1441-1453.2004

J. Riese, S. Boecker, W. Hohenberger, P. Klein, and W. Haupt, Microdialysis: A New Technique to Monitor Perioperative Human Peritoneal Mediator Production, Surgical Infections, vol.4, issue.1, pp.11-15, 2003.
DOI : 10.1089/109629603764655236

M. Rowland and T. M. Tozer, Small volume of distribution, Clinical pharmacokinetics: concepts and applications, pp.438-450, 1989.

J. S. Solomkin, J. E. Mazuski, E. J. Baron, R. G. Sawyer, A. B. Nathens et al., Guidelines for the Selection of Anti-infective Agents for Complicated Intra-abdominal Infections, Clinical Infectious Diseases, vol.37, issue.8, pp.997-1005, 2003.
DOI : 10.1086/378702

T. Sommer and J. F. Larsen, Intraperitoneal and intraluminal microdialysis in the detection of experimental regional intestinal ischaemia, British Journal of Surgery, vol.91, issue.7, pp.855-861, 2004.
DOI : 10.1002/bjs.4586

I. Tegeder, A. Schmidtko, L. Bräutigam, A. Kirchbaum, G. Geisslinger et al., Tissue distribution of imipenem in critically ill patients, Clinical Pharmacology & Therapeutics, vol.71, issue.5, pp.325-333, 2002.
DOI : 10.1067/mcp.2002.122526

J. Ungerstedt, G. Nowak, B. Ericzon, and U. Ungerstedt, INTRAPERITONEAL MICRODIALYSIS (IPM), Shock, vol.20, issue.1, pp.91-96, 2003.
DOI : 10.1097/01.shk.0000070904.21762.36

K. A. Wichterman, A. E. Baue, and I. H. Chaudry, Sepsis and septic shock???A review of laboratory models and a proposal, Journal of Surgical Research, vol.29, issue.2, pp.189-201, 1980.
DOI : 10.1016/0022-4804(80)90037-2