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Microdialysis study of imipenem distribution in the peritoneal fluid of rats with experimental acute pancreatitis.

Abstract : Imipenem distribution was characterized by microdialysis in the peritoneal fluid of rats with experimental pancreatitis. The ratios of peritoneal fluid to blood area under unbound concentration-versus-time curves were close to unity, suggesting that imipenem was not degraded in peritoneal fluid.
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https://www.hal.inserm.fr/inserm-00319484
Contributor : Sandrine Marchand <>
Submitted on : Monday, September 8, 2008 - 3:30:48 PM
Last modification on : Wednesday, January 8, 2020 - 3:30:07 PM
Long-term archiving on: : Saturday, November 26, 2016 - 1:33:46 AM

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Sandrine Lefeuvre, Sandrine Marchand, Isabelle Lamarche, Claudine Pariat, William Couet. Microdialysis study of imipenem distribution in the peritoneal fluid of rats with experimental acute pancreatitis.. Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2008, 52 (4), pp.1516-8. ⟨10.1128/AAC.01474-07⟩. ⟨inserm-00319484⟩

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