Microdialysis study of imipenem distribution in the peritoneal fluid of rats with experimental acute pancreatitis. - Archive ouverte HAL Access content directly
Journal Articles Antimicrobial Agents and Chemotherapy Year : 2008

Microdialysis study of imipenem distribution in the peritoneal fluid of rats with experimental acute pancreatitis.

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Abstract

Imipenem distribution was characterized by microdialysis in the peritoneal fluid of rats with experimental pancreatitis. The ratios of peritoneal fluid to blood area under unbound concentration-versus-time curves were close to unity, suggesting that imipenem was not degraded in peritoneal fluid.
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inserm-00319484 , version 1 (08-09-2008)

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Sandrine Lefeuvre, Sandrine Marchand, Isabelle Lamarche, Claudine Pariat, William Couet. Microdialysis study of imipenem distribution in the peritoneal fluid of rats with experimental acute pancreatitis.. Antimicrobial Agents and Chemotherapy, 2008, 52 (4), pp.1516-8. ⟨10.1128/AAC.01474-07⟩. ⟨inserm-00319484⟩
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