Skip to Main content Skip to Navigation
Journal articles

Pontin and reptin, two related ATPases with multiple roles in cancer.: Pontin and Reptin in cancer

Abstract : Studies in model organisms or cultured human cells suggest potential implications in carcinogenesis for the AAA+ ATPases Pontin and Reptin. Both proteins are associated with several chromatin-remodeling complexes and have many functions including transcriptional regulation, DNA damage repair, and telomerase activity. They also interact with major oncogenic actors such as beta-catenin and c-myc and regulate their oncogenic function. We only now begin to get insight into the role of Pontin and Reptin in human cancers. [Cancer Res 2008;68(17):6873-6].
Document type :
Journal articles
Complete list of metadatas

Cited literature [26 references]  Display  Hide  Download

https://www.hal.inserm.fr/inserm-00306362
Contributor : Jean Rosenbaum <>
Submitted on : Thursday, September 3, 2009 - 1:40:12 PM
Last modification on : Thursday, February 7, 2019 - 4:44:01 PM
Long-term archiving on: : Saturday, November 26, 2016 - 12:21:51 AM

File

Huber.pdf
Files produced by the author(s)

Identifiers

Collections

Citation

Otmar Huber, Ludovic Ménard, Valérie Haurie, Alexandra Nicou, Danièle Taras, et al.. Pontin and reptin, two related ATPases with multiple roles in cancer.: Pontin and Reptin in cancer. Cancer Research, American Association for Cancer Research, 2008, 68 (17), pp.6873-6. ⟨10.1158/0008-5472.CAN-08-0547⟩. ⟨inserm-00306362⟩

Share

Metrics

Record views

610

Files downloads

635