Skip to Main content Skip to Navigation
Journal articles

Dendritic cells dysfunction in tumour environment.

Abstract : Several studies indicate that most tumours are immunogenic and they rarely succeed to induce an efficient immune response. Many mechanisms have been involved in the tumour escape from host immune surveillance. The tumour microenvironment has emerged as an important component contributing to dendritic cells (DCs) dysfunction. There is evidence that DCs play a key role in the induction of tumour-specific immune responses, especially via cross-priming through MHC-class I antigens presentation. In this review we will discuss the potential role of the tumour microenvironment in DCs dysfunction.
Document type :
Journal articles
Complete list of metadata

Cited literature [101 references]  Display  Hide  Download
Contributor : Karim Bennaceur Connect in order to contact the contributor
Submitted on : Wednesday, July 2, 2008 - 3:09:46 PM
Last modification on : Tuesday, May 17, 2022 - 10:26:04 AM
Long-term archiving on: : Saturday, November 26, 2016 - 12:26:11 AM


 Restricted access
To satisfy the distribution rights of the publisher, the document is embargoed until : jamais

Please log in to resquest access to the document




Karim Bennaceur, Jessica Chapman, Leila Brikci-Nigassa, Kamel Sanhadji, Jean-Louis Touraine, et al.. Dendritic cells dysfunction in tumour environment.. Cancer Letters, Elsevier, 2008, epub ahead of print. ⟨10.1016/j.canlet.2008.05.017⟩. ⟨inserm-00292735⟩



Record views