Skip to Main content Skip to Navigation
Journal articles

Dispensing of anxiolytics and hypnotics in southeastern France: demographic factors and determinants of geographic variations.

Abstract : We examined geographic variations in the dispensing of anxiolytics and hypnotics (AX-HY) and their determinants at the canton level in southeastern France. Data were collected from the 2005 outpatient database of the Southeastern France General Health Insurance Fund, covering more than 70% of the population. We calculated the annual age-adjusted prevalence rates of subjects filling prescriptions for AX-HY at least once (to measure 'overall use') and at least six times ('chronic use'), assessed geographic variations with the extremal quotient and weighted coefficient of variation, and conducted simple and multiple linear regression analysis to study their determinants. Prevalence rates of overall and chronic AX-HY use were 15.5% and 5.9%, respectively, and varied significantly between cantons, by a factor of 3-4. The prevalence of mental illness and that of chronic illness were independently and positively associated with overall and chronic use; unemployment rates and mean family income were positively associated only with overall use. Density of general practitioners did not explain geographic variations. These results provide a basis for targeting interventions to reduce AX-HY use and promoting appropriate discontinuation. Future studies should examine trends in those geographic variations.
Document type :
Journal articles
Complete list of metadatas

Cited literature [16 references]  Display  Hide  Download

https://www.hal.inserm.fr/inserm-00282216
Contributor : Aurélie Bocquier <>
Submitted on : Tuesday, June 2, 2009 - 4:22:49 PM
Last modification on : Thursday, April 11, 2019 - 1:04:14 PM
Long-term archiving on: : Friday, May 28, 2010 - 5:48:16 PM

Identifiers

Collections

Citation

Aurélie Bocquier, Kamel Bezzou, Steve Nauleau, Pierre Verger. Dispensing of anxiolytics and hypnotics in southeastern France: demographic factors and determinants of geographic variations.. Fundamental and Clinical Pharmacology, Wiley, 2008, 22 (3), pp.323-33. ⟨10.1111/j.1472-8206.2008.00587.x⟩. ⟨inserm-00282216⟩

Share

Metrics

Record views

594

Files downloads

595