O. Abe, H. Yamasue, S. Aoki, M. Suga, H. Yamada et al., Aging in the CNS: Comparison of gray/white matter volume and diffusion tensor data, Neurobiology of Aging, vol.29, issue.1, 2006.
DOI : 10.1016/j.neurobiolaging.2006.09.003

J. Allen, J. Bruss, C. Brown, and H. Damasio, Normal neuroanatomical variation due to age: The major lobes and a parcellation of the temporal region, Neurobiology of Aging, vol.26, issue.9, pp.1245-60, 2005.
DOI : 10.1016/j.neurobiolaging.2005.05.023

J. Baron and C. Godeau, Human Aging, pp.591-604, 2000.
DOI : 10.1016/B978-012692545-6/50022-2
URL : https://hal.archives-ouvertes.fr/hal-01438686

J. Baron, G. Chételat, B. Desgranges, G. Perchey, B. Landeau et al., In Vivo Mapping of Gray Matter Loss with Voxel-Based Morphometry in Mild Alzheimer's Disease, NeuroImage, vol.14, issue.2, pp.298-309, 2001.
DOI : 10.1006/nimg.2001.0848

L. Beason-held, M. Kraut, and S. I. Resnick, I. Longitudinal changes in aging brain function, Neurobiology of Aging, vol.29, issue.4, 2006.
DOI : 10.1016/j.neurobiolaging.2006.10.031

L. Beason-held, M. Kraut, S. Resnick, and . Ii, II. Temporal patterns of longitudinal change in aging brain function, Neurobiology of Aging, vol.29, issue.4, 2006.
DOI : 10.1016/j.neurobiolaging.2006.11.011

F. Bernard, B. Desgranges, F. Eustache, and J. Baron, Neural correlates of age-related verbal episodic memory decline: A PET study with combined subtraction/correlation analysis, Neurobiology of Aging, vol.28, issue.10, 2006.
DOI : 10.1016/j.neurobiolaging.2006.07.004
URL : https://hal.archives-ouvertes.fr/inserm-00277803

R. Buckner, Memory and Executive Function in Aging and AD, Neuron, vol.44, issue.1, pp.195-208, 2004.
DOI : 10.1016/j.neuron.2004.09.006

R. Cabeza, Hemispheric asymmetry reduction in older adults: The HAROLD model., Psychology and Aging, vol.17, issue.1
DOI : 10.1037/0882-7974.17.1.85

R. Cabeza and L. Nyberg, Imaging Cognition II: An Empirical Review of 275 PET and fMRI Studies, Journal of Cognitive Neuroscience, vol.14, issue.4, pp.1-47, 2000.
DOI : 10.1017/S135561779800160X

C. Calautti, C. Serrati, and J. Baron, Effects of Age on Brain Activation During Auditory-Cued Thumb-to-Index Opposition : A Positron Emission Tomography Study, Stroke, vol.32, issue.1, pp.139-185, 2001.
DOI : 10.1161/01.STR.32.1.139

D. Cardebat, B. Doyon, M. Puel, P. Goulet, and Y. Joanette, Evocation lexicale formelle et sémantique chez des sujets normaux: performances et dynamiques de production en fonction du sexe, de l'âge et du niveau d'étude, Acta neurol Belg, vol.90, pp.207-224, 1990.

G. Chételat, B. Desgranges, V. De-la-sayette, F. Viader, F. Eustache et al., Mapping gray matter loss with voxel-based morphometry in mild cognitive impairment, NeuroReport, vol.13, issue.15, pp.1939-1982, 2002.
DOI : 10.1097/00001756-200210280-00022

C. Lalevée, L. Doze, F. Dupuy, B. Hannequin, D. Baron et al., Dissociating atrophy and hypometabolism impact on episodic memory in mild cognitive impairment, Brain, vol.126, pp.1955-67, 2003.

H. Chugani, A Critical Period of Brain Development: Studies of Cerebral Glucose Utilization with PET, Preventive Medicine, vol.27, issue.2, pp.184-192, 1998.
DOI : 10.1006/pmed.1998.0274

C. Fallet-bianco, F. Pasquier, F. Lebert, H. Petit, D. Menza et al., The biochemical pathway of neurofibrillary degeneration in aging and Alzheimer's disease, Neurology, vol.52, pp.1156-65, 1999.

B. Desgranges, J. Baron, and F. Eustache, The Functional Neuroanatomy of Episodic Memory: The Role of the Frontal Lobes, the Hippocampal Formation, and Other Areas, NeuroImage, vol.8, issue.2
DOI : 10.1006/nimg.1998.0359

B. Desgranges, J. Baron, C. Lalevée, G. B. Viader, F. De-la-sayette et al., The neural substrates of episodic memory impairment in Alzheimer's disease as revealed by FDG-PET: relationship to degree of deterioration, Brain, vol.125, issue.5, pp.1116-1140, 2002.
DOI : 10.1093/brain/awf097

B. Desgranges, J. Baron, G. B. Chételat, G. Lalevée, C. Viader et al., The neural basis of intrusions in free recall and cued recall: a PET study

B. Dickerson, D. Salat, D. Greve, E. Chua, E. Rand-giovannetti et al., Increased hippocampal activation in mild cognitive impairment compared to normal aging and AD, Neurology, vol.65, issue.3, pp.404-415, 2005.
DOI : 10.1212/01.wnl.0000171450.97464.49

R. Sutherland, The aging hippocampus: cognitive, biochemical and structural findings

F. Eustache, B. Desgranges, and C. L. Lalevée, évaluation clinique de la mémoire, Revue Neurologique (Paris), vol.154, pp.18-32, 1998.

F. Eustache, B. Desgranges, G. B. De-la-sayette, V. Baron, and J. , Entorhinal cortex disruption causes memory deficit in early Alzheimer's disease as shown by PET, Neuroreport, vol.12, issue.4, pp.683-688, 2001.
DOI : 10.1097/00001756-200103260-00013

A. Fotenos, A. Snyder, L. Girton, J. Morris, and R. Buckner, Normative estimates of cross-sectional and longitudinal brain volume decline in aging and AD, Neurology, vol.64, issue.6, pp.1032-1041, 2005.
DOI : 10.1212/01.WNL.0000154530.72969.11

G. Garraux, E. Salmon, C. Degueldre, C. Lemaire, S. Laureys et al., Comparison of Impaired Subcortico-Frontal Metabolic Networks in Normal Aging, Subcortico-Frontal Dementia, and Cortical Frontal Dementia, NeuroImage, vol.10, issue.2, pp.149-62, 1999.
DOI : 10.1006/nimg.1999.0463

C. Good, I. Johnsrude, J. Ashburner, R. Henson, K. Friston et al., A Voxel-Based Morphometric Study of Ageing in 465 Normal Adult Human Brains, NeuroImage, vol.14, issue.1, pp.21-36, 2001.
DOI : 10.1006/nimg.2001.0786

C. Grady, Functional brain imaging and age-related changes in cognition, Biological Psychology, vol.54, issue.1-3, pp.259-81, 2000.
DOI : 10.1016/S0301-0511(00)00059-4

S. Grieve, C. Clark, L. Williams, A. Peduto, and E. Gordon, Preservation of limbic and paralimbic structures in aging, Human Brain Mapping, vol.4, issue.4, pp.391-401, 2005.
DOI : 10.1002/hbm.20115

K. Herholz, Discrimination between Alzheimer Dementia and Controls by Automated Analysis of Multicenter FDG PET, NeuroImage, vol.17, issue.1, pp.302-318, 2002.
DOI : 10.1006/nimg.2002.1208

V. Ibanez, P. Pietrini, M. Furey, G. Alexander, P. Millet et al., Resting state brain glucose metabolism is not reduced in normotensive healthy men during aging, after correction for brain atrophy, Brain Research Bulletin, vol.63, issue.2, pp.147-54, 2004.
DOI : 10.1016/j.brainresbull.2004.02.003

J. Hesselink, Effects of age on tissues and regions of the cerebrum and cerebellum, Neurobiol Aging, vol.22, pp.581-94, 2001.

T. Jernigan and A. Gamst, Changes in volume with age???consistency and interpretation of observed effects, Neurobiology of Aging, vol.26, issue.9, pp.1271-1275, 2005.
DOI : 10.1016/j.neurobiolaging.2005.05.016

K. Kantarci, C. Jack, and . Jr, Neuroimaging in Alzheimer disease: an evidence-based review, Neuroimaging Clinics of North America, vol.13, issue.2, pp.197-209, 2003.
DOI : 10.1016/S1052-5149(03)00025-X

J. Lehmbeck, S. Brassen, W. Weber-fahr, and D. Braus, Combining voxel-based morphometry and diffusion tensor imaging to detect age-related brain changes, NeuroReport, vol.17, issue.5, pp.467-70, 2006.
DOI : 10.1097/01.wnr.0000209012.24341.7f

H. Lemaître, F. Crivello, B. Grassiot, A. Alpérovitch, C. Tzourio et al., Age- and sex-related effects on the neuroanatomy of healthy elderly, NeuroImage, vol.26, issue.3, pp.900-911, 2005.
DOI : 10.1016/j.neuroimage.2005.02.042

M. Lepage, R. Habib, and E. Tulving, Hippocampal PET activations of memory encoding and retrieval: The HIPER model, Hippocampus, vol.8, issue.4, pp.313-335, 1998.
DOI : 10.1002/(SICI)1098-1063(1998)8:4<313::AID-HIPO1>3.0.CO;2-I

R. Liu, L. Lemieux, G. Bell, S. Sisodiya, S. Shorvon et al., A longitudinal study of brain morphometrics using quantitative magnetic resonance imaging and difference image analysis, NeuroImage, vol.20, issue.1, pp.22-33, 2003.
DOI : 10.1016/S1053-8119(03)00219-2

A. Martin, K. Friston, J. Colebatch, and R. Frackowiak, Decreases in Regional Cerebral Blood Flow with Normal Aging, Journal of Cerebral Blood Flow & Metabolism, vol.17, issue.4, pp.684-693, 1991.
DOI : 10.1097/00004728-198012000-00001

H. Matsuda, N. Kitayama, T. Ohnishi, T. Asada, S. Nakano et al., Longitudinal evaluation of both morphologic and functional changes in the same individuals with Alzheimer " s disease, J Nucl Med, vol.43, pp.304-315, 2002.

H. Matsuda, T. Ohnishi, T. Asada, Z. Li, H. Kanetaka et al., Correction for partial-volume effects on brain perfusion SPECT in healthy men, J Nucl Med, vol.44, pp.1243-52, 2003.

S. Mattis, Mental status examination for organic mental syndrome in the elderly patient In: Mental Status Examination for Organic Mental Syndrome in the Elderly Patients, pp.77-101, 1976.

K. Meguro, J. Constans, P. Courtheoux, T. J. Viader, F. Yamadori et al., Atrophy of the corpus callosum correlates with white matter lesions in patients with cerebral ischaemia, Neuroradiology, vol.42, issue.6, pp.416-425, 2000.
DOI : 10.1007/s002340000302

C. Meltzer, J. Becker, J. Price, and E. Moses-kolko, Positron emission tomography imaging of the aging brain, Neuroimaging Clinics of North America, vol.13, issue.4, pp.759-67, 2003.
DOI : 10.1016/S1052-5149(03)00108-4

C. Meltzer, M. Cantwell, P. Greer, D. Ben-eliezer, G. Smith et al., Does cerebral blood flow decline in healthy aging? A PET study with partial-volume correction, J Nucl Med, vol.41, pp.1842-1850, 2000.

P. Pietrini and D. Eidelberg, The metabolic topography of normal aging, J Cereb Blood Flow Metab, vol.16, pp.385-98, 1996.

A. Morcom, C. Good, R. Frackowiak, and M. Rugg, Age effects on the neural correlates of successful memory encoding, Brain, vol.126, issue.1, pp.213-242, 2003.
DOI : 10.1093/brain/awg020

L. Mosconi, W. Tsui, D. Santi, S. Li, J. Rusinek et al., Reduced hippocampal metabolism in MCI and AD: Automated FDG-PET image analysis, Neurology, vol.64, issue.11, pp.1860-1867, 2005.
DOI : 10.1212/01.WNL.0000163856.13524.08

C. Davatzikos and J. Frost, Measurement of radiotracer concentration in brain gray matter using positron emission tomography: MRI-based correction for partial volume effects, J Cereb Blood Flow Metab, vol.12, pp.571-83, 1992.

P. Nestor, T. Fryer, M. Ikeda, and J. Hodges, Retrosplenial cortex (BA29/30) hypometabolism in mild cognitive impairment (prodromal Alzheimer " s disease), Eur J Neurosci, vol.18, pp.1-5, 2003.

J. Pariente, S. Cole, R. Henson, C. L. Kennedy, A. Rossor et al., Alzheimer's patients engage an alternative network during a memory task, Annals of Neurology, vol.111, issue.6, pp.870-879, 2005.
DOI : 10.1002/ana.20653

D. Park and A. Gutchess, Aging, cognition, and culture: a neuroscientific perspective, Neuroscience & Biobehavioral Reviews, vol.26, issue.7
DOI : 10.1016/S0149-7634(02)00072-6

J. Persson and L. Nyberg, Altered brain activity in healthy seniors: what does it mean?, Prog Brain Res, vol.157, pp.45-56, 2006.
DOI : 10.1016/S0079-6123(06)57004-9

M. Petit-taboué, B. Landeau, J. Desson, B. Desgranges, and J. Baron, Effects of Healthy Aging on the Regional Cerebral Metabolic Rate of Glucose Assessed with Statistical Parametric Mapping, NeuroImage, vol.7, issue.3, pp.176-84, 1998.
DOI : 10.1006/nimg.1997.0318

A. Pfefferbaum, E. Sullivan, M. Rosenbloom, D. Mathalon, and K. Lim, A Controlled Study of Cortical Gray Matter and Ventricular Changes in Alcoholic Men Over a 5-Year Interval, Archives of General Psychiatry, vol.55, issue.10, pp.905-917, 1998.
DOI : 10.1001/archpsyc.55.10.905

D. Prayer, G. Kasprian, E. Krampl, B. Ulm, L. Witzani et al., MRI of normal fetal brain development, European Journal of Radiology, vol.57, issue.2, pp.199-216, 2006.
DOI : 10.1016/j.ejrad.2005.11.020

M. Quarantelli, K. Berkouk, A. Prinster, B. Landeau, C. Svarer et al., Integrated software for the analysis of brain PET/SPECT studies with partial-volume-effect correction, J Nucl Med, vol.45, pp.192-201, 2004.

M. Rados, J. M. Kostovic, and I. , In vitro MRI of brain development, European Journal of Radiology, vol.57, issue.2, pp.187-98, 2006.
DOI : 10.1016/j.ejrad.2005.11.019

N. Raz, Ageing and the brain, In: Encyclopedia of Life Sciences, 2001.

N. Raz, Aging of the brain and its impact on cognitive performance: integration of structural and functional findings In: Handbook of aging and cognition-II (Craik FIM, pp.1-90, 2000.

N. Raz, U. Lindenberger, K. Rodrigue, K. Kennedy, D. Head et al., Regional Brain Changes in Aging Healthy Adults: General Trends, Individual Differences and Modifiers, Cerebral Cortex, vol.15, issue.11, pp.1676-89, 2005.
DOI : 10.1093/cercor/bhi044

N. Raz, F. Gunning-dixon, D. Head, K. Rodrigue, A. Williamson et al., Aging, sexual dimorphism, and hemispheric asymmetry of the cerebral cortex: replicability of regional differences in volume, Neurobiology of Aging, vol.25, issue.3, pp.377-96, 2004.
DOI : 10.1016/S0197-4580(03)00118-0

N. Raz, K. Rodrigue, D. Head, K. Kennedy, and J. Acker, Differential aging of the medial temporal lobe: A study of a five-year change, Neurology, vol.62, issue.3, pp.433-441, 2004.
DOI : 10.1212/01.WNL.0000106466.09835.46

A. Thornton and J. Acker, Selective aging of the human cerebral cortex observed in vivo: Differential vulnerability of the prefrontal gray matter, Cereb Cortex, vol.7, pp.268-82, 1997.

S. Resnick, D. Pham, M. Kraut, A. Zonderman, and C. Davatzikos, Longitudinal magnetic resonance imaging studies of older adults: A shrinking brain, J Neurosci, vol.23, pp.3295-3296, 2003.

S. Resnick, A. Goldszal, C. Davatzikos, S. Golski, M. Kraut et al., One-year Age Changes in MRI Brain Volumes in Older Adults, Cerebral Cortex, vol.10, issue.5, pp.464-72, 2000.
DOI : 10.1093/cercor/10.5.464

M. Rettmann, M. Kraut, J. Prince, and S. Resnick, Cross-sectional and Longitudinal Analyses of Anatomical Sulcal Changes Associated with Aging, Cerebral Cortex, vol.16, issue.11, pp.1584-94, 2006.
DOI : 10.1093/cercor/bhj095

O. Rousset, Y. Ma, and A. Evans, Correction for partial volume effects in PET: principle and validation, J Nucl Med, vol.39, pp.904-915, 1998.

O. Rousset, Y. Ma, D. Wong, and A. Evans, Pixel-Versus Region-Based Partial Volume Correction in PET, In: Quantitative Functional Brain Imaging with Positron Emission Tomography, pp.67-75, 1998.
DOI : 10.1016/B978-012161340-2/50012-3

O. Rousset and H. Zaidi, Correction for Partial Volume Effects in Emission Tomography
DOI : 10.1007/0-387-25444-7_8

D. Salat, R. Buckner, A. Snyder, D. Greve, R. Desikan et al., Thinning of the Cerebral Cortex in Aging, Cerebral Cortex, vol.14, issue.7, pp.721-751, 2004.
DOI : 10.1093/cercor/bhh032

R. Scahill, C. Frost, R. Jenkins, J. Whitwell, M. Rossor et al., A Longitudinal Study of Brain Volume Changes in Normal Aging Using Serial Registered Magnetic Resonance Imaging, Archives of Neurology, vol.60, issue.7, pp.989-94, 2003.
DOI : 10.1001/archneur.60.7.989

D. Schacter and A. Wagner, Medial temporal lobe activations in fMRI and PET studies of episodic encoding and retrieval, Hippocampus, vol.4, issue.1, pp.7-24, 1999.
DOI : 10.1002/(SICI)1098-1063(1999)9:1<7::AID-HIPO2>3.0.CO;2-K

D. Schacter, C. Savage, N. Alpert, S. Rauch, and M. Albert, The role of hippocampus and frontal cortex in age- related memory changes, NeuroReport, vol.7, issue.6, pp.1165-1174, 1996.
DOI : 10.1097/00001756-199604260-00014

R. Sperling, J. Bates, E. Chua, A. Cocchiarella, D. Rentz et al., fMRI studies of associative encoding in young and elderly controls and mild Alzheimer's disease, Journal of Neurology, Neurosurgery & Psychiatry, vol.74, issue.1, pp.44-50, 2003.
DOI : 10.1136/jnnp.74.1.44

E. Sullivan, L. Marsh, and A. Pfefferbaum, Preservation of hippocampal volume throughout adulthood in healthy men and women, Neurobiology of Aging, vol.26, issue.7, pp.1093-1101, 2005.
DOI : 10.1016/j.neurobiolaging.2004.09.015

D. Tisserand, M. Van-boxtel, J. Pruessner, P. Hofman, A. Evans et al., A Voxel-based Morphometric Study to Determine Individual Differences in Gray Matter Density Associated with Age and Cognitive Change Over Time, Cerebral Cortex, vol.14, issue.9, pp.966-73, 2004.
DOI : 10.1093/cercor/bhh057

A. Toga, P. Thompson, and E. Sowell, Mapping brain maturation, Trends in Neurosciences, vol.29, issue.3, pp.148-59, 2006.
DOI : 10.1016/j.tins.2006.01.007
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113697

E. Tulving, S. Kapur, F. Craik, M. Moscovitch, and S. Houle, Hemispheric encoding/retrieval asymmetry in episodic memory: positron emission tomography findings., Proceedings of the National Academy of Sciences, vol.91, issue.6, pp.2016-2036, 1994.
DOI : 10.1073/pnas.91.6.2016

K. Van-laere and R. Dierckx, Brain Perfusion SPECT: Age- and Sex-related Effects Correlated with Voxel-based Morphometric Findings in Healthy Adults, Radiology, vol.221, issue.3, pp.810-817, 2001.
DOI : 10.1148/radiol.2213010295

K. Walhovd, A. Fjell, I. Reinvang, A. Lundervold, A. Dale et al., Effects of age on volumes of cortex, white matter and subcortical structures, Neurobiology of Aging, vol.26, issue.9, pp.1261-70, 2005.
DOI : 10.1016/j.neurobiolaging.2005.05.020

M. Willis, T. Ketter, T. Kimbrell, M. George, P. Herscovitch et al., Age, sex and laterality effects on cerebral glucose metabolism in healthy adults, Psychiatry Research: Neuroimaging, vol.114, issue.1, pp.23-37, 2002.
DOI : 10.1016/S0925-4927(01)00126-3

M. Yamada, Brain FDG PET study of normal aging in Japanese: effect of atrophy correction, Eur J Nucl Med Mol Imaging, vol.32, pp.794-805, 2005.

H. Zaidi, T. Ruest, F. Schoenahl, and M. Montandon, Comparative assessment of statistical brain MR image segmentation algorithms and their impact on partial volume correction in PET, NeuroImage, vol.32, issue.4, pp.1591-607, 2006.
DOI : 10.1016/j.neuroimage.2006.05.031

G. Zuendorf, N. Kerrouche, K. Herholz, and J. Baron, Efficient principal component analysis for multivariate 3D voxel-based mapping of brain functional imaging data sets as applied to FDG-PET and normal aging, Human Brain Mapping, vol.15, issue.1, pp.13-21, 2003.
DOI : 10.1002/hbm.10069