M. Bingham, T. Ong, W. Ingledew, and H. Mcardle, ATP-dependent copper transporter, in the Golgi apparatus of rat hepatocytes, transports Cu(II) not Cu(I), Am J Physiol, vol.271, pp.741-747, 1996.

X. Yang, N. Miura, Y. Kawarada, K. Terada, K. Petrukhin et al., Two forms of Wilson disease protein produced by alternative splicing are localized in distinct cellular compartments, Biochemical Journal, vol.326, issue.3, pp.897-902, 1997.
DOI : 10.1042/bj3260897

H. Roelofsen, H. Wolters, M. Van-luyn, N. Miura, F. Kuipers et al., Copper-induced apical trafficking of ATP7B in polarized hepatoma cells provides a mechanism for biliary copper excretion, Gastroenterology, vol.119, issue.3, pp.782-93, 2000.
DOI : 10.1053/gast.2000.17834

G. Ihrke, E. Neufeld, T. Meads, M. Shanks, D. Cassio et al., WIF-B cells: an in vitro model for studies of hepatocyte polarity, The Journal of Cell Biology, vol.123, issue.6, pp.1761-75, 1993.
DOI : 10.1083/jcb.123.6.1761

M. Harada, S. Sakisaka, K. Terada, R. Kimura, T. Kawaguchi et al., Role of ATP7B in biliary copper excretion in a human hepatoma cell line and normal rat hepatocytes, Gastroenterology, vol.118, issue.5, pp.921-929, 2000.
DOI : 10.1016/S0016-5085(00)70178-8

L. Fontaine, S. Theophilos, M. Firth, S. Gould, R. Parton et al., Effect of the toxic milk mutation (tx) on the function and intracellular localization of Wnd, the murine homologue of the Wilson copper ATPase, Human Molecular Genetics, vol.10, issue.4, pp.361-70, 2001.
DOI : 10.1093/hmg/10.4.361

M. Schaefer, R. Hopkins, M. Failla, and J. Gitlin, Hepatocyte-specific localization and copper-dependent trafficking of the Wilson's disease protein in the liver, Am J Physiol, vol.276, pp.639-685, 1999.

M. Cater, L. Fontaine, S. Shield, K. Deal, Y. Mercer et al., ATP7B Mediates Vesicular Sequestration of Copper: Insight Into Biliary Copper Excretion, Gastroenterology, vol.130, issue.2, pp.493-506, 2006.
DOI : 10.1053/j.gastro.2005.10.054

S. Lutsenko, N. Barnes, M. Bartee, and O. Dmitriev, Function and Regulation of Human Copper-Transporting ATPases, Physiological Reviews, vol.87, issue.3, pp.1011-1057, 2007.
DOI : 10.1152/physrev.00004.2006

D. Cox, Genes of the copper pathway, Am J Hum Genet, vol.56, pp.828-862, 1995.

P. Mohan, M. Failla, I. Bremner, A. Arthur-smith, and B. Kerzner, Biliary copper excretion in the neonatal rat: role of glutathione and metallothionein, Hepatology, vol.21, pp.1051-1058, 1995.

C. Wijmenga, T. Muller, I. Murli, T. Brunt, H. Feichtinger et al., Endemic Tyrolean infantile cirrhosis is not an allelic variant of Wilson's disease, European Journal of Human Genetics, vol.6, issue.6, pp.624-632, 1998.
DOI : 10.1038/sj.ejhg.5200235

T. Muller, B. Van-de-sluis, W. Muller, P. Pearson, and C. Wijmenga, Non-Indian childhood cirrhosis, Eur J Med Res, vol.4, pp.293-300, 1999.

G. Maggiore, D. Giacomo, C. Sessa, F. Burgio, and G. , Idiopathic Hepatic Copper Toxicosis in a Child, Journal of Pediatric Gastroenterology and Nutrition, vol.6, issue.6, pp.980-983, 1987.
DOI : 10.1097/00005176-198711000-00028

X. Peng, B. Grosse, L. Tiec, B. Nicolas, V. Delagebeaudeuf et al., How to induce non-polarized cells of hepatic origin to express typical hepatocyte polarity: generation of new highly polarized cell models with developed and functional bile canaliculi, Cell and Tissue Research, vol.13, issue.2, pp.233-276, 2006.
DOI : 10.1007/s00441-005-0067-2

B. Stevenson, J. Siliciano, M. Mooseker, and D. Goodenough, Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia, The Journal of Cell Biology, vol.103, issue.3, pp.755-66, 1986.
DOI : 10.1083/jcb.103.3.755

J. Bartles, L. Braiterman, A. Hubbard, C. Paulusma, M. Kothe et al., Endogenous and exogenous domain markers of the rat hepatocyte plasma membrane Zonal down-regulation and redistribution of the multidrug resistance protein 2 during bile duct ligation in rat liver, J Cell Biol Hepatology, vol.10031, pp.1126-38684, 1985.

R. Lebovitz, K. Takeyasu, and D. Fambrough, Molecular characterization and expression of the (Na+ + K+)-ATPase alpha-subunit in Drosophila melanogaster, Embo J, vol.8, pp.193-202, 1989.

J. Barriocanal, J. Bonifacino, L. Yuan, and I. Sandoval, Biosynthesis, glycosylation, movement through the Golgi system, and transport to lysosomes by an N-linked carbohydrate-independent mechanism of three lysosomal integral membrane proteins, J Biol Chem, vol.261, pp.16755-63, 1986.

L. Yuan, J. Barriocanal, J. Bonifacino, and I. Sandoval, Two integral membrane proteins located in the cis-middle and trans-part of the Golgi system acquire sialylated N-linked carbohydrates and display different turnovers and sensitivity to cAMP-dependent phosphorylation, The Journal of Cell Biology, vol.105, issue.1, pp.215-242, 1987.
DOI : 10.1083/jcb.105.1.215

J. Alcalde, G. Egea, and I. Sandoval, gp74 a membrane glycoprotein of the cis-Golgi network that cycles through the endoplasmic reticulum and intermediate compartment, The Journal of Cell Biology, vol.124, issue.5, pp.649-65, 1994.
DOI : 10.1083/jcb.124.5.649

S. Martinez-arca, V. Lalioti, and I. Sandoval, Intracellular targeting and retention of the glucose transporter GLUT4 by the perinuclear storage compartment involves distinct carboxyl-tail motifs, J Cell Sci, vol.113, pp.1705-1720, 2000.

P. Meier, E. Sztul, A. Reuben, J. Boyer, B. Ross et al., Structural and functional polarity of canalicular and basolateral plasma membrane vesicles isolated in high yield from rat liver Gluconeogenesis in the perfused rat liver, J Cell Biol Biochem J, vol.98101, pp.284-92, 1966.

M. Pinna, P. Bauduin, D. Touraud, M. Monduzzi, B. Ninham et al., Hofmeister Effects in Biology:?? Effect of Choline Addition on the Salt-Induced Super Activity of Horseradish Peroxidase and Its Implication for Salt Resistance of Plants, The Journal of Physical Chemistry B, vol.109, issue.34, pp.16511-16515, 2005.
DOI : 10.1021/jp051897v

P. Lowe, K. Kan, S. Barnwell, R. Sharma, and R. Coleman, Transcytosis and paracellular movements of horseradish peroxidase across liver parenchymal tissue from blood to bile. Effects of alpha-naphthylisothiocyanate and colchicine, Biochemical Journal, vol.229, issue.2, pp.529-566, 1985.
DOI : 10.1042/bj2290529

M. Harada, T. Kawaguchi, H. Kumemura, K. Terada, H. Ninomiya et al., The Wilson Disease Protein ATP7B Resides in the Late Endosomes with Rab7 and the Niemann-Pick C1 Protein, The American Journal of Pathology, vol.166, issue.2, pp.499-510, 2005.
DOI : 10.1016/S0002-9440(10)62272-9

M. Harada, H. Kumemura, S. Sakisaka, S. Shishido, E. Taniguchi et al., Wilson disease protein ATP7B is localized in the late endosomes in a polarized human hepatocyte cell line, International Journal of Molecular Medicine, vol.11, pp.293-301, 2003.
DOI : 10.3892/ijmm.11.3.293

Y. Guo, L. Nyasae, L. Braiterman, and A. Hubbard, NH2-terminal signals in ATP7B Cu-ATPase mediate its Cu-dependent anterograde traffic in polarized hepatic cells, AJP: Gastrointestinal and Liver Physiology, vol.289, issue.5, pp.904-920, 2005.
DOI : 10.1152/ajpgi.00262.2005

M. Bartee and S. Lutsenko, Hepatic copper-transporting ATPase ATP7B: function and inactivation at the molecular and cellular level, BioMetals, vol.2, issue.3-4, pp.627-664, 2007.
DOI : 10.1007/s10534-006-9074-3

C. Van-itallie and J. Anderson, CLAUDINS AND EPITHELIAL PARACELLULAR TRANSPORT, Annual Review of Physiology, vol.68, issue.1, pp.403-432, 2006.
DOI : 10.1146/annurev.physiol.68.040104.131404

T. Jons, D. Wittschieber, A. Beyer, C. Meier, A. Brune et al., K+-ATP-channel-related protein complexes: potential transducers in the regulation of epithelial tight junction permeability, Journal of Cell Science, vol.119, issue.15, pp.3087-97, 2006.
DOI : 10.1242/jcs.03041

G. Laube, J. Roper, J. Pitt, S. Sewing, U. Kistner et al., Ultrastructural localization of Shaker-related potassium channel subunits and synapse-associated protein 90 to septate-like junctions in rat cerebellar Pinceaux, Molecular Brain Research, vol.42, issue.1, pp.51-61, 1996.
DOI : 10.1016/S0169-328X(96)00120-9

S. Hadj-rabia, L. Baala, P. Vabres, D. Hamel-teillac, E. Jacquemin et al., Claudin-1 gene mutations in neonatal sclerosing cholangitis associated with ichthyosis: A tight junction disease, Gastroenterology, vol.127, issue.5, pp.1386-90, 2004.
DOI : 10.1053/j.gastro.2004.07.022

K. Shin, V. Fogg, and B. Margolis, Tight Junctions and Cell Polarity, Annual Review of Cell and Developmental Biology, vol.22, issue.1, pp.207-242, 2006.
DOI : 10.1146/annurev.cellbio.22.010305.104219

A. Soler, C. Marano, M. Bryans, R. Miller, L. Garulacan et al., Activation of NF-??B is necessary for the restoration of the barrier function of an epithelium undergoing TNF-??-induced apoptosis, European Journal of Cell Biology, vol.78, issue.1, pp.56-66, 1999.
DOI : 10.1016/S0171-9335(99)80007-7

T. Yamamoto, T. Kojima, M. Murata, K. Takano, M. Go et al., IL-1?? regulates expression of Cx32, occludin, and claudin-2 of rat hepatocytes via distinct signal transduction pathways, Experimental Cell Research, vol.299, issue.2, pp.427-468, 2004.
DOI : 10.1016/j.yexcr.2004.06.011

A. Klomp, B. Van-de-sluis, L. Klomp, C. Wijmenga, M. Breen et al., The ubiquitously expressed MURR1 protein is absent in canine copper toxicosis Genetic mapping of the copper toxicosis locus in Bedlington terriers to dog chromosome 10, in a region syntenic to human chromosome region 2p13-p16, J Hepatol Hum Mol Genet, vol.398, pp.703-712, 1999.

J. Olson, J. Fujimoto, and R. Peterson, Three methods for measuring the increase in the capacity of the distended biliary tree in the rat produced by ??-naphthylisothiocyanate treatment, Toxicology and Applied Pharmacology, vol.42, issue.1, pp.33-43, 1977.
DOI : 10.1016/0041-008X(77)90194-6