Structure-antinociceptive activity of neurotensin and some novel analogues in the periaqueductal gray region of the brainstem, Brain Res, vol.557, pp.227-235, 1991. ,
Neurotensin receptor interaction with dopaminergic systems in the guinea-pig brain shown by neurotensin receptor antagonists, Eur. J. Pharmacol, vol.255, pp.167-174, 1994. ,
Effects of neurotensin on dopamine release and metabolism in the rat striatum and nucleus accumbens: cross-validation using in vivo voltametry and microdialysis, Neuroscience, vol.34, pp.699-705, 1990. ,
New 3-amino-pyrazole for treatment of pathological states caused by dopaminergic system dysfunction. Eur, 1992. ,
SR 48692 inhibits neurotensin-induced [ 3 H]dopamine release in rat striatal slices and mesencephalic cultures, Eur. J. Pharmacol, vol.253, pp.289-291, 1994. ,
Mesencephalic dopaminergic neurons in primary cultures express functional neurotensin receptors, J. Neurosci, vol.12, pp.1409-1415, 1992. ,
The isolation of a new hypotensive peptide, neurotensin, from bovine hypothalami, J. Biol. Chem, vol.248, pp.6854-6861, 1973. ,
Characterization of the binding of ,
Relationship between the inhibition constant (K i ) and the concentration of inhibitor which causes 50 percent inhibition (IC 50 ) of an enzymatic reaction ,
The nonpeptide neurotensin antagonist, SR 48692, used as a tool to reveal putative neurotensin receptor subtypes, Br. J. Pharmacol, vol.112, pp.352-354, 1994. ,
The regional distribution and chromatographic characterization of neurotensin-like immunoreactivity in the rat central nervous system, J. Neurochem, vol.38, pp.992-999, 1982. ,
Different binding epitopes on the NK1 receptor for substance P and non-peptide antagonist, Nature, vol.362, pp.345-348, 1993. ,
Biochemical and pharmacological profile of a potent and selective nonpeptide antagonist of neurotensin receptor ,
Dopaminergic control of 125 I-labeled neurotensin binding site density in corticolimbic structures of the rat brain, Proc. Natl. Acad. Sci. USA, pp.6203-6207, 1986. ,
The species selectivity of chemically distinct tachykinin nonpeptide antagonists is dependent on common divergent residues of the rat and human neurokinin-1 receptors, Mol. Pharmacol, vol.45, pp.294-299, 1994. ,
The rat gene encoding neurotensin and neuromedin N: Structure, tissue-specific expression, and evolution of axon sequences, J Biol Chem, vol.263, pp.4963-4968, 1988. ,
Pharmacology and biochemistry of neurotensin receptors, Rev. Basic Clin. Pharmacol, vol.5, pp.397-486, 1985. ,
[ 3 H]SR 48692, a new nonpeptide neurotensin antagonist radioligand, reveals distinct agonist and antagonist binding domains on the rat neurotensin receptor, Society for Neuroscience Abstracts, vol.20, p.27, 1994. ,
The Neurobiology of Neurotensin, Ann. N.Y. Acad. Sci, vol.668, pp.1-371, 1992. ,
Two populations of neurotensin binding sites in murine brain: discrimination by the antihistamine levocabastine reveals markedly different radioautographic distribution, Eur. J. Pharmacol, vol.140, pp.285-293, 1987. ,
In vivo and in vitro structure-activity studies with peptide and pseudopeptide neurotensin analogs suggest the existence of distinct central neurotensin receptor subtypes, J. Pharmacol. Exp. Ther, vol.268, pp.328-336, 1994. ,
Neurotensin in the human brain, Neuroscience, vol.22, pp.499-524, 1987. ,
The seventh transmembrane domain of gastrin/CCK receptors contributes to non-peptide antagonist binding, Biochem. Biophys. Res. Commun, vol.201, pp.1382-1389, 1994. ,
Distribution of neurotensin binding sites in rat brain: A light microscopic radioautographic study using monoiodo [ 125 I]Tyr 3 -neurotensin, Neuroscience, vol.22, pp.525-536, 1987. ,
LIGAND: A versatile computerized approach for characterization of ligand-binding systems, Anal. Biochem, vol.107, pp.220-239, 1980. ,
Blockade of neurotensin binding in the rat hypothalamus and of the central action of neurotensin on the hypothalamic-pituitary-adrenal axis with non-peptide receptor antagonists, Neuroendocrinology, vol.59, pp.572-578, 1994. ,
Neurotensin receptor expression in the rat forebrain and midbrain: A combined analysis by in situ hybridization and receptor autoradiography, J. Comp. Neurol, vol.341, pp.407-419, 1994. ,
Neurotensin receptors are located on dopamine-containing neurons in the rat midbrain, Nature, vol.294, pp.587-589, 1981. ,
The Rat Brain in Stereotaxic Coordinates, 1986. ,
Heterogeinity of 3 H neurotensin binding: studies with dynorphin, L-156,903 and levocabastine, Brain Res, vol.457, pp.212-218, 1988. ,
Comparative localization of neurotensin receptors on nigrostriatal and mesolimbic dopaminergic terminals, Brain Res, vol.327, pp.385-389, 1985. ,
The brain of the guinea pig in stereotaxic coordinates, Arch. Sci. biol, vol.61, pp.1-37, 1977. ,
Interaction between neurotensin and dopamine in the brain: Morphofunctional and clinical evidence, Ann. N.Y. Acad. Sci, vol.668, pp.217-231, 1992. ,
Characterization and visualization of neurotensin binding to receptor sites in human brain, Biochem. Biophys. Res. Commun, vol.120, pp.206-213, 1984. ,
Preparation of neurotensin selectively iodinated on the tyrosine 3 residue. Biological activity and binding properties on mammalian neurotensin receptors, Biochem. Biophys. Res. Commun, vol.120, pp.812-819, 1984. ,
Characterization and autoradiographic distribution of neurotensin binding sites in the human brain, Brain Res, vol.348, pp.375-380, 1985. ,
Evidence for a displaceable non-specific [ 3 H] neurotensin binding site in rat brain, Naunyn-Schmiedeberg's Arch. Pharmacol, vol.333, pp.400-405, 1986. ,
Different subcellular localization of neurotensin receptor and neurotensin acceptor sites in the rat brain dopaminergic system, J. Neurochem, vol.50, pp.1026-1033, 1988. ,
Electrophysiological effects of neurotensin on dopaminergic neurones of the ventral tegmental area of the rat in vitro, Neuropharmacology, vol.28, pp.949-954, 1989. ,
Photoaffinity labeling of rat pancreatic cholecystokinin type A receptor antagonist binding sites demonstrates the presence of a truncated cholecystokinin type A receptor, Mol. Pharmacol, vol.45, pp.599-607, 1994. ,
Correspondence between high affinity 125 I-neurotensin binding sites and dopaminergic neurons in the rat substantia nigra and ventral tegmental area: A combined radioautographic and immunohistochemical light microscopic study, J. Comp. Neurol, vol.279, pp.128-137, 1989. ,
Direct demonstration of three different states of the pancreatic cholecystokinin receptor, Proc. Natl. Acad ,
Structure and functional expression of the cloned rat neurotensin receptor, Neuron, vol.4, pp.847-854, 1990. ,
Cloning and expression of a complementary DNA encoding a high affinity human neurotensin receptor, FEBS Lett, vol.317, pp.139-142, 1993. ,
Rat cardiac muscarinic receptors. I. Effects of guanine nucleotides on high-and low-affinity binding sites, Mol. Pharmacol, vol.21, pp.581-588, 1982. ,