N. Hunt and G. Grau, Cytokines: accelerators and brakes in the pathogenesis of cerebral malaria, Trends in Immunology, vol.24, issue.9, pp.491-500, 2003.
DOI : 10.1016/S1471-4906(03)00229-1

D. Souza, J. Riley, and E. , Cerebral malaria: the contribution of studies in animal models to our understanding of immunopathogenesis, Microbes and Infection, vol.4, issue.3, pp.291-300, 2002.
DOI : 10.1016/S1286-4579(02)01541-1

A. Garcia, S. Marquet, and B. Bucheton, Linkage analysis of blood Plasmodium falciparum levels: interest of the 5q31-q33 chromosome region, Am J Trop Med Hyg, vol.58, pp.705-714, 1998.

A. Jepson, F. Sisay-joof, and W. Banya, Genetic linkage of mild malaria to the major histocompatibility complex in Gambian children: study of affected sibling pairs, BMJ, vol.315, issue.7100, pp.96-103, 1997.
DOI : 10.1136/bmj.315.7100.96

L. Flori, S. Sawadogo, C. Esnault, N. Delahaye, F. Fumoux et al., Linkage of mild malaria to the major histocompatibility complex in families living in Burkina Faso, Human Molecular Genetics, vol.12, issue.4, pp.375-383, 2003.
DOI : 10.1093/hmg/ddg033

J. Lou, R. Lucas, and G. Grau, Pathogenesis of Cerebral Malaria: Recent Experimental Data and Possible Applications for Humans, Clinical Microbiology Reviews, vol.14, issue.4, pp.810-830, 2001.
DOI : 10.1128/CMR.14.4.810-820.2001

V. Combes, N. Coltel, and M. Alibert, ABCA1 Gene Deletion Protects against Cerebral Malaria, The American Journal of Pathology, vol.166, issue.1, pp.295-302, 2005.
DOI : 10.1016/S0002-9440(10)62253-5

URL : https://hal.archives-ouvertes.fr/hal-00165766

D. Puthier, F. Joly, and M. Irla, A General Survey of Thymocyte Differentiation by Transcriptional Analysis of Knockout Mouse Models, The Journal of Immunology, vol.173, issue.10, pp.6109-6127, 2004.
DOI : 10.4049/jimmunol.173.10.6109

F. Bertucci, S. Salas, and S. Eysteries, Gene expression profiling of colon cancer by DNA microarrays and correlation with histoclinical parameters, Oncogene, vol.23, issue.7, pp.1377-91, 2004.
DOI : 10.1038/sj.onc.1207262

M. Eisen, P. Spellman, P. Brown, and D. Botstein, Cluster analysis and display of genome-wide expression patterns, Proceedings of the National Academy of Sciences, vol.95, issue.25, pp.14863-14871, 1998.
DOI : 10.1073/pnas.95.25.14863

A. Fortin, M. Stevenson, and P. Gros, Complex genetic control of susceptibility to malaria in mice, Genes and Immunity, vol.3, issue.4, pp.177-86, 2002.
DOI : 10.1038/sj.gene.6363841

G. Grau, L. Fajardo, P. Piguet, B. Allet, P. Lambert et al., Tumor necrosis factor (cachectin) as an essential mediator in murine cerebral malaria, Science, vol.237, issue.4819, pp.1210-1212, 1987.
DOI : 10.1126/science.3306918

C. Engwerda, T. Mynott, S. Sawhney, D. Souza, J. Bickle et al., Locally Up-regulated Lymphotoxin ??, Not Systemic Tumor Necrosis Factor ??, Is the Principle Mediator of Murine Cerebral Malaria, The Journal of Experimental Medicine, vol.156, issue.10, pp.1371-1378, 2002.
DOI : 10.1016/S0140-6736(00)04217-3

M. Ashburner, C. Ball, and J. Blake, Gene Ontology: tool for the unification of biology, Nature Genetics, vol.9, issue.1
DOI : 10.1038/75556

J. Pardo, A. Bosque, and R. Brehm, Apoptotic pathways are selectively activated by granzyme A and/or granzyme B in CTL-mediated target cell lysis, The Journal of Cell Biology, vol.161, issue.3, pp.457-68, 2004.
DOI : 10.1074/jbc.M005390200

J. Pardo, S. Balkow, A. Anel, and M. Simon, Granzymes are essential for natural killer cell-mediated and perf-facilitated tumor control, European Journal of Immunology, vol.32, issue.10, pp.2881-2888, 2002.
DOI : 10.1002/1521-4141(2002010)32:10<2881::AID-IMMU2881>3.0.CO;2-K

B. Motyka, G. Korbutt, and M. Pinkoski, Mannose 6-Phosphate/Insulin-like Growth Factor II Receptor Is a Death Receptor for Granzyme B during Cytotoxic T Cell???Induced Apoptosis, Cell, vol.103, issue.3, pp.491-500, 2000.
DOI : 10.1016/S0092-8674(00)00140-9

J. Nitcheu, O. Bonduelle, and C. Combadiere, Perforin-Dependent Brain-Infiltrating Cytotoxic CD8+ T Lymphocytes Mediate Experimental Cerebral Malaria Pathogenesis, The Journal of Immunology, vol.170, issue.4, pp.2221-2229, 2003.
DOI : 10.4049/jimmunol.170.4.2221

S. Potter, G. Chaudhri, A. Hansen, and N. Hunt, Fas and perforin contribute to the pathogenesis of murine cerebral malaria, Redox Report, vol.159, issue.162, pp.333-338, 1999.
DOI : 10.1002/(SICI)1098-1136(199702)19:2<91::AID-GLIA1>3.0.CO;2-C

F. Denizot, J. Brunet, and P. Roustan, Novel structures CTLA-2?? and CTLA-2?? expressed in mouse activated T cells and mast cells and homologous to cysteine proteinase proregions, European Journal of Immunology, vol.157, issue.4, pp.631-636, 1989.
DOI : 10.1002/eji.1830190409

J. Van-beek, P. Chan, M. Bernaudin, E. Petit, E. Mackenzie et al., Glial responses, clusterin, and complement in permanent focal cerebral ischemia in the mouse, Glia, vol.735, issue.1, pp.39-50, 2000.
DOI : 10.1002/(SICI)1098-1136(200007)31:1<39::AID-GLIA40>3.0.CO;2-1

H. Ball, H. Macdougall, I. Mcgregor, and N. Hunt, Cyclooxygenase???2 in the Pathogenesis of Murine Cerebral Malaria, The Journal of Infectious Diseases, vol.189, issue.4, pp.751-759, 2004.
DOI : 10.1086/381503

L. Spielman, D. Winger, L. Ho, P. Aisen, E. Shohami et al., Induction of the complement component C1qB in brain of transgenic mice with neuronal overexpression of human cyclooxygenase-2, Acta Neuropathologica, vol.103, issue.2, pp.157-62, 2002.
DOI : 10.1007/s004010100447

T. Davis, M. Sturm, and Y. Zhang, Platelet-activating factor and lipid metabolism in acute malaria, Journal of Infection, vol.26, issue.3, pp.279-85, 1993.
DOI : 10.1016/0163-4453(93)95405-8

W. Lafuse, D. Brown, L. Castle, and B. Zwilling, Cloning and characterization of a novel cDNA that is IFN-gamma-induced in mouse peritoneal macrophages and encodes a putative GTP-binding protein, J Leukoc Biol, vol.57, pp.477-83, 1995.

J. Smith and H. Herschman, The Glucocorticoid Attenuated Response Genes GARG-16, GARG-39, and GARG-49/IRG2 Encode Inducible Proteins Containing Multiple Tetratricopeptide Repeat Domains, Archives of Biochemistry and Biophysics, vol.330, issue.2, pp.290-300, 1996.
DOI : 10.1006/abbi.1996.0256

A. De-baey, B. Fellerhoff, S. Maier, S. Martinozzi, U. Weidle et al., Complex Expression Pattern of the TNF Region Gene LST1 through Differential Regulation, Initiation, and Alternative Splicing, Genomics, vol.45, issue.3, pp.591-600, 1997.
DOI : 10.1006/geno.1997.4963

C. Zhu, K. Rao, and H. Xiong, Activation of the Murine Interleukin-12 p40 Promoter by Functional Interactions between NFAT and ICSBP, Journal of Biological Chemistry, vol.278, issue.41, pp.39372-82, 2003.
DOI : 10.1074/jbc.M306441200

E. Decker, N. Nehmann, E. Kampen, H. Eibel, P. Zipfel et al., Early growth response proteins (EGR) and nuclear factors of activated T cells (NFAT) form heterodimers and regulate proinflammatory cytokine gene expression, Nucleic Acids Research, vol.31, issue.3, pp.911-932, 2003.
DOI : 10.1093/nar/gkg186

A. Neish, A. Williams, H. Palmer, M. Whitley, and C. T. , Functional analysis of the human vascular cell adhesion molecule 1 promoter, Journal of Experimental Medicine, vol.176, issue.6, pp.1583-93, 1992.
DOI : 10.1084/jem.176.6.1583

C. Vestergaard, C. Johansen, K. Otkjaer, M. Deleuran, and L. Iversen, Tumor necrosis factor-??-induced CTACK/CCL27 (cutaneous T-cell-attracting chemokine) production in keratinocytes is controlled by nuclear factor ??B, Cytokine, vol.29, issue.2, pp.49-55, 2005.
DOI : 10.1016/j.cyto.2004.09.008

T. Bouwmeester, A. Bauch, and H. Ruffner, A physical and functional map of the human TNF-??/NF-??B signal transduction pathway, Nature Cell Biology, vol.9, issue.2, pp.97-105, 2004.
DOI : 10.1021/ac950914h

J. Lou, Y. Gasche, and L. Zheng, Differential reactivity of brain microvascular endothelial cells to TNF reflects the genetic susceptibility to cerebral malaria, European Journal of Immunology, vol.272, issue.12, pp.3989-4000, 1998.
DOI : 10.1002/(SICI)1521-4141(199812)28:12<3989::AID-IMMU3989>3.0.CO;2-X

A. Sexton, R. Good, and D. Hansen, Transcriptional Profiling Reveals Suppressed Erythropoiesis, Up???Regulated Glycolysis, and Interferon???Associated Responses in Murine Malaria, The Journal of Infectious Diseases, vol.189, issue.7, pp.1245-56, 2004.
DOI : 10.1086/382596

G. Grau, P. Piguet, P. Vassalli, and P. Lambert, Tumor-Necrosis Factor and other Cytokines in Cerebral Malaria: Experimental and Clinical Data, Immunological Reviews, vol.23, issue.1, pp.49-70, 1989.
DOI : 10.1016/0035-9203(86)90180-X

D. Yanez, D. Manning, A. Cooley, W. Weidanz, and H. Van-der-heyde, Participation of lymphocyte subpopulations in the pathogenesis of experimental murine cerebral malaria, J Immunol, vol.157, pp.1620-1624, 1996.

V. Amani, A. Vigario, and E. Belnoue, Involvement of IFN-?? receptor-mediated signaling in pathology and anti-malarial immunity induced by Plasmodium berghei infection, European Journal of Immunology, vol.30, issue.6, pp.1646-55, 2000.
DOI : 10.1002/1521-4141(200006)30:6<1646::AID-IMMU1646>3.0.CO;2-0

R. Lucas, P. Juillard, and E. Decoster, Crucial role of tumor necrosis factor (TNF) receptor 2

J. Knight, I. Udalova, and A. Hill, A polymorphism that affects OCT-1 binding to the TNF promoter region is associated with severe malaria, Nature Genetics, vol.22, issue.2, pp.145-50, 1999.
DOI : 10.1038/9649

O. Koch, A. Awomoyi, and S. Usen, Gene Promoter Polymorphisms and Susceptibility to Cerebral Malaria, The Journal of Infectious Diseases, vol.185, issue.11, pp.1684-1691, 2002.
DOI : 10.1086/340516

K. Artavanis-tsakonas and E. Riley, Innate Immune Response to Malaria: Rapid Induction of IFN-?? from Human NK Cells by Live Plasmodium falciparum-Infected Erythrocytes, The Journal of Immunology, vol.169, issue.6, pp.2956-63, 2002.
DOI : 10.4049/jimmunol.169.6.2956

I. Scragg, M. Hensmann, C. Bate, and D. Kwiatkowski, Early cytokine induction by Plasmodium falciparum is not a classical endotoxin-like process, European Journal of Immunology, vol.29, issue.08, pp.2636-2680, 1999.
DOI : 10.1002/(SICI)1521-4141(199908)29:08<2636::AID-IMMU2636>3.3.CO;2-P

D. Hansen, K. Evans, D. Ombrain, and M. , The Natural Killer Complex Regulates Severe Malarial Pathogenesis and Influences Acquired Immune Responses to Plasmodium berghei ANKA, Infection and Immunity, vol.73, issue.4, pp.2288-97, 2005.
DOI : 10.1128/IAI.73.4.2288-2297.2005