Anomalous apical plasma membrane phenotype in CK8-deficient mice indicates a novel role for intermediate filaments in the polarization of simple epithelia, J. Cell Sci, vol.114, pp.563-575, 2001. ,
Leaky junctions and cholestasis: A tight correlation, Gastroenterology, vol.110, issue.5, pp.1662-1665, 1996. ,
DOI : 10.1053/gast.1996.v110.agast961662
The subcellular organization of Madin-Darby canine kidney cells during the formation of a polarized epithelium, The Journal of Cell Biology, vol.109, issue.6, pp.2817-2832, 1989. ,
DOI : 10.1083/jcb.109.6.2817
Biogenesis of the rat hepatocyte plasma membrane in vivo: comparison of the pathways taken by apical and basolateral proteins using subcellular fractionation, The Journal of Cell Biology, vol.105, issue.3, pp.1241-1251, 1987. ,
DOI : 10.1083/jcb.105.3.1241
Endoplasmic reticulum of animal cells and its organization into structural and functional domains, Int. Rev. Cytol, vol.205, pp.149-214, 2001. ,
DOI : 10.1016/S0074-7696(01)05004-5
Expression and localization of hepatocyte domainspecific plasma membrane proteins in hepatoma x fibroblast hybrids and in hepatoma dedifferentiated variants, J. Cell Sci, vol.111, pp.3437-3450, 1998. ,
Investigation of the hepatotoxicity profile of chemical entities using Liverbeads?? and WIF-B9 in vitro models, Toxicology in Vitro, vol.20, issue.6, pp.1051-1059, 2006. ,
DOI : 10.1016/j.tiv.2006.01.013
Sequence and functional characterization of a third inositol trisphosphate receptor subtype, IP3R-3, expressed in pancreatic islets, kidney, gastrointestinal tract, and other tissues, J. Biol. Chem, vol.268, pp.11356-11363, 1993. ,
Efficient in vitro vectorial transport of a fluorescent conjugated bile acid analogue by polarized hepatic hybrid WIF-B and WIF-B9 cells, 1998. ,
Usefulness of Liposomes Loaded with Cytostatic Bile Acid Derivatives to Circumvent Chemotherapy Resistance of Enterohepatic Tumors, Molecular Pharmacology, vol.63, issue.3, pp.742-750, 2003. ,
DOI : 10.1124/mol.63.3.742
Differential regulation of rodent hepatocyte and oval cell proliferation by interferon ?, Hepatology, vol.277, issue.4, pp.906-915, 2005. ,
DOI : 10.1002/hep.20645
MRP2, a human conjugate export pump, is present and transports fluo 3 into apical vacuoles of Hep G2 cells, Am. J, 2000. ,
Complex inheritance of familial hypercholanemia with associated mutations in TJP2 and BAAT, Nature Genetics, vol.34, issue.1, pp.91-96, 2003. ,
DOI : 10.1038/ng1147
Hybrid cell lines constitute a potential reservoir of polarized cells: isolation and study of highly differentiated hepatoma-derived hybrid cells able to form functional bile canaliculi in vitro, The Journal of Cell Biology, vol.115, issue.5, pp.1397-1408, 1991. ,
DOI : 10.1083/jcb.115.5.1397
Expression, localization, and inducibility by bile acids of hepatobiliary transporters in the new polarized rat hepatic cell lines, Can 3???1 and Can 10, Cell and Tissue Research, vol.30, issue.3, pp.447-460, 2007. ,
DOI : 10.1007/s00441-007-0494-3
URL : https://hal.archives-ouvertes.fr/inserm-00276792
Transdifferentiation of hepatocyte-like cells from the human hepatoma HepaRG cell line through bipotent progenitor, Hepatology, vol.103, issue.4, pp.957-967, 2007. ,
DOI : 10.1002/hep.21536
URL : https://hal.archives-ouvertes.fr/hal-00690471
The polarized hepatic human/rat hybrid WIF 12-1 and WIF-B cells communicate efficientlyin vitro via connexin 32-constituted gap junctions, Hepatology, vol.9, issue.1, pp.164-172, 1998. ,
DOI : 10.1002/hep.510280122
The formation of bile canaliculi in human hepatoma cell lines, Hepatology, vol.36, issue.5, pp.834-842, 1990. ,
DOI : 10.1002/hep.1840110519
Mammalian PAR-1 determines epithelial lumen polarity by organizing the microtubule cytoskeleton, The Journal of Cell Biology, vol.79, issue.5, pp.717-727, 2004. ,
DOI : 10.1016/S0962-8924(03)00036-9
Par-1 promotes a hepatic mode of apical protein trafficking in MDCK cells, Proc.Natl.Acad.Sci. USA, pp.13792-13797, 2004. ,
DOI : 10.1073/pnas.0403684101
The type 3 inositol 1,4,5-trisphosphate receptor is concentrated at the tight junction level in polarized MDCK cells, Journal of Cell Science, vol.116, issue.13, pp.2791-2803, 2003. ,
DOI : 10.1242/jcs.00482
URL : https://hal.archives-ouvertes.fr/hal-00306513
signals in multicellular systems of rat hepatocytes, Biochemical Journal, vol.304, issue.2, pp.585-594, 1994. ,
DOI : 10.1042/bj3040585
Establishment of hepatic cell polarity in the rat hepatoma-human fibroblast hybrid WIF-B9. A biphasic phenomenon going from a simple epithelial polarized phenotype to an hepatic polarized one, J. Cell Sci, vol.109, pp.1623-1635, 1996. ,
Spatiotemporal expression of catenins, ZO-1, and occludin during early polarization of hepatic WIF-B9 cells, Am. J. Physiol. Cell Physiol, vol.280, pp.527-539, 2001. ,
Up-regulation of basolateral multidrug resistance protein 3 (Mrp3) in cholestatic rat liver, Hepatology, vol.34, issue.2, pp.351-359, 2001. ,
DOI : 10.1053/jhep.2001.26213
Expression of inositol 1,4,5-trisphosphate receptor isoforms in rat cirrhosis, Hepatology, vol.272, issue.4, pp.1018-1026, 1999. ,
DOI : 10.1002/hep.510300421
Phalloidin-induced cholestasis: a microfilament-mediated change in junctional complex permeability., Proc.Natl.Acad.Sci. USA, pp.2229-2233, 1980. ,
DOI : 10.1073/pnas.77.4.2229
Expression and subcellular localization of aquaporin water channels in the polarized hepatocyte cell line, BMC Physiology, vol.5, issue.1, p.13, 2005. ,
DOI : 10.1186/1472-6793-5-13
Isolated rat hepatocyte couplets: a primary secretory unit for electrophysiologic studies of bile secretory function., Proceedings of the National Academy of Sciences, vol.81, issue.20, pp.6516-6520, 1984. ,
DOI : 10.1073/pnas.81.20.6516
The use of isolated rat hepatocyte couplets in hepatobiliary physiology, Journal of Hepatology, vol.10, issue.3, pp.387-394, 1990. ,
DOI : 10.1016/0168-8278(90)90152-H
Infection of a human hepatoma cell line by hepatitis B virus, Proc. Natl. Acad. Sci. U S A 99, pp.15655-15660, 2002. ,
The human hepatoma HepaRG cells: A highly differentiated model for studies of liver metabolism and toxicity of xenobiotics, Chemico-Biological Interactions, vol.168, issue.1, pp.66-73, 2007. ,
DOI : 10.1016/j.cbi.2006.12.003
NH2-terminal signals in ATP7B Cu-ATPase mediate its Cu-dependent anterograde traffic in polarized hepatic cells, AJP: Gastrointestinal and Liver Physiology, vol.289, issue.5, 2005. ,
DOI : 10.1152/ajpgi.00262.2005
Claudin-1 gene mutations in neonatal sclerosing cholangitis associated with ichthyosis: A tight junction disease, Gastroenterology, vol.127, issue.5, pp.1386-1390, 2004. ,
DOI : 10.1053/j.gastro.2004.07.022
Regulation of cell morphology and cytochrome P450 expression in human hepatocytes by extracellular matrix and cell-cell interactions, Cell Tissue Res, vol.306, pp.85-99, 2001. ,
Three-dimensional polarization sensitizes hepatocytes to Fas/CD95 apoptotic signalling, Journal of Cell Science, vol.118, issue.12, pp.2763-2773, 2005. ,
DOI : 10.1242/jcs.02403
Role of ATP7B in biliary copper excretion in a human hepatoma cell line and normal rat hepatocytes, Gastroenterology, vol.118, issue.5, pp.921-928, 2000. ,
DOI : 10.1016/S0016-5085(00)70178-8
SR-BI Undergoes Cholesterol-stimulated Transcytosis to the Bile Canaliculus in Polarized WIF-B Cells, Journal of Biological Chemistry, vol.282, issue.2, 2007. ,
DOI : 10.1074/jbc.M604627200
The Spatial Distribution of Inositol 1,4,5-Trisphosphate Receptor Isoforms Shapes Ca2+ Waves, Journal of Biological Chemistry, vol.282, issue.13, 2007. ,
DOI : 10.1074/jbc.M700746200
Rho Kinase, Myosin-II, and p42/44 MAPK Control Extracellular Matrix-mediated Apical Bile Canalicular Lumen Morphogenesis in HepG2 Cells, Molecular Biology of the Cell, vol.17, issue.7, pp.3291-3303, 2006. ,
DOI : 10.1091/mbc.E06-01-0067
Hepatocyte surface polarity, The Liver, pp.189-214, 1994. ,
WIF-B cells: an in vitro model for studies of hepatocyte polarity, The Journal of Cell Biology, vol.123, issue.6, pp.1761-1775, 1993. ,
DOI : 10.1083/jcb.123.6.1761
Microtubules are more stable and more highly acetylated in ethanol-treated hepatic cells, Journal of Hepatology, vol.44, issue.5, pp.963-970, 2006. ,
DOI : 10.1016/j.jhep.2005.07.007
Role of cytokeratin intermediate filaments in transhepatic transport and canalicular secretion, Hepatology, vol.61, issue.3, pp.435-448, 1990. ,
DOI : 10.1002/hep.1840110315
Radixin deficiency causes conjugated hyperbilirubinemia with loss of Mrp2 from bile canalicular membranes, Nature Genetics, vol.31, issue.3, pp.320-325, 2002. ,
DOI : 10.1038/ng905
Trafficking of Canalicular ABC Transporters in Hepatocytes, Annual Review of Physiology, vol.64, issue.1, pp.595-608, 2002. ,
DOI : 10.1146/annurev.physiol.64.081501.155793
Use of human-derived liver cell lines for the detection of environmental and dietary genotoxicants; current state of knowledge, Toxicology, vol.198, issue.1-3, pp.315-328, 2004. ,
DOI : 10.1016/j.tox.2004.02.008
Mice with chimeric human livers: who says supermodels have to be tall? Hepatology 41, pp.703-706, 2005. ,
Changes in the expression and localization of hepatocellular transporters and radixin in primary biliary cirrhosis, Journal of Hepatology, vol.39, issue.5, pp.693-702, 2003. ,
DOI : 10.1016/S0168-8278(03)00410-0
Regulation of the blood?biliary barrier: interaction between gap and tight junctions in hepatocytes, Medical Electron Microscopy, vol.36, issue.3, pp.157-164, 2003. ,
DOI : 10.1007/s00795-003-0220-5
Keratin 8 and 18 mutations are risk factors for developing liver disease of multiple etiologies, Proc. Natl. Acad. Sci. USA, pp.6063-6068, 2003. ,
DOI : 10.1073/pnas.0936165100
Trafficking of the bile salt export pump from the Golgi to the canalicular membrane is regulated by the p38 MAP kinase, Gastroenterology, vol.126, issue.2, pp.541-553, 2004. ,
DOI : 10.1053/j.gastro.2003.11.003
Functional expression of sinusoidal and canalicular hepatic drug transporters in the differentiated human hepatoma HepaRG cell line, European Journal of Pharmaceutical Sciences, vol.28, issue.1-2, pp.109-117, 2006. ,
DOI : 10.1016/j.ejps.2006.01.004
URL : https://hal.archives-ouvertes.fr/hal-00699571
Calcium signaling in the hepatocyte, The Liver, pp.537-554, 2001. ,
The Class I Alcohol Dehydrogenase Gene Is Glucocorticoid-Responsive in the Rat Hepatoma Microcell Hybrid Cell Line, 11-3, Alcoholism: Clinical and Experimental Research, vol.269, issue.6, pp.1430-1434, 1995. ,
DOI : 10.1016/0378-1119(90)90093-7
Formation of plasma membrane domains in rat hepatocytes and hepatoma cell lines in culture, J. Cell Sci, vol.90, pp.79-92, 1988. ,
Stores Has a Key Role in Nonmuscle Cell Signaling and Function : Figure 1, The Journal of Cell Biology, vol.10, issue.6, pp.1395-1398, 1998. ,
DOI : 10.1074/jbc.272.37.23389
Reestablishment of cell polarity of rat hepatocytes in primary culture, Hepatology, vol.66, issue.1, pp.198-205, 1993. ,
DOI : 10.1002/hep.1840180129
Multistep mechanism of polarized Ca2+ wave patterns in hepatocytes, Am. J. Physiol. Gastrointest. Liver Physiol, vol.267, pp.338-349, 1994. ,
Communication via gap junctions modulates bile secretion in the isolated perfused rat liver, Gastroenterology, vol.116, issue.5, pp.1176-1183, 1999. ,
DOI : 10.1016/S0016-5085(99)70021-1
Defective propagation of signals generated by sympathetic nerve stimulation in the liver of connexin32-deficient mice., Proc. Natl. Acad, 1996. ,
DOI : 10.1073/pnas.93.18.9565
Adaptation of core mechanisms to generate cell polarity, Nature, vol.104, issue.6933, pp.766-774, 2003. ,
DOI : 10.1038/nature01602
Reversible induction of rat hepatoma cell polarity with bile acids, J. Cell Sci, vol.113, pp.4241-4251, 2000. ,
Expression of the apical conjugate export pump, Mrp2, in the polarized hepatoma cell line, WIF-B, Hepatology, vol.34, issue.5, pp.1332-1340, 1998. ,
DOI : 10.1002/hep.510280523
Transcytotic Efflux from Early Endosomes Is Dependent on Cholesterol and Glycosphingolipids in Polarized Hepatic Cells, Molecular Biology of the Cell, vol.14, issue.7, pp.2689-2705, 2003. ,
DOI : 10.1091/mbc.E02-12-0816
Origin and characterization of a human bipotent liver progenitor cell line???, Gastroenterology, vol.126, issue.4, pp.1147-1156, 2004. ,
DOI : 10.1053/j.gastro.2004.01.002
Enterohepatic transport of bile salts and genetics of cholestasis, Journal of Hepatology, vol.43, issue.2, pp.342-357, 2005. ,
DOI : 10.1016/j.jhep.2005.03.017
How to induce non-polarized cells of hepatic origin to express typical hepatocyte polarity: generation of new highly polarized cell models with developed and functional bile canaliculi, Cell and Tissue Research, vol.13, issue.2, pp.233-243, 2006. ,
DOI : 10.1007/s00441-005-0067-2
STAT5B-mediated Growth Hormone Signaling Is Organized by Highly Dynamic Microtubules in Hepatic Cells, Journal of Biological Chemistry, vol.280, issue.2, pp.1123-1131, 2005. ,
DOI : 10.1074/jbc.M409918200
URL : https://hal.archives-ouvertes.fr/hal-00013821
Functional specialization of stable and dynamic microtubules in protein traffic in WIF-B cells, J. Cell Biol, vol.142, pp.153-165, 1998. ,
Exogenous MAL Reroutes Selected Hepatic Apical Proteins into the Direct Pathway in WIF-B Cells, Molecular Biology of the Cell, vol.18, issue.7, pp.2707-2715, 2007. ,
DOI : 10.1091/mbc.E07-02-0096
Bile acid secretion and direct targeting of mdr1-green fluorescent protein from Golgi to the canalicular membrane in polarized WIF-B cells, J. Cell Sci, vol.112, pp.4535-4545, 1999. ,
PPAR??2 regulates lipogenesis and lipid accumulation in steatotic hepatocytes, AJP: Endocrinology and Metabolism, vol.288, issue.6, pp.1195-1205, 2005. ,
DOI : 10.1152/ajpendo.00513.2004
Protein 4.1N does not interact with the inositol 1,4,5-trisphosphate receptor in an epithelial cell line, Cell Calcium, vol.38, issue.5, pp.469-480, 2005. ,
DOI : 10.1016/j.ceca.2005.06.038
Cell Surface Polarity in Epithelia, Annual Review of Cell Biology, vol.1, issue.1, pp.243-288, 1985. ,
DOI : 10.1146/annurev.cb.01.110185.001331
Bile canaliculus formation in cultured HEPG2 cells, Lab. Invest, vol.68, pp.652-662, 1993. ,
A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis, Nat. Genet, vol.20, pp.233-238, 1998. ,
Cell Polarity Development and Protein Trafficking in Hepatocytes Lacking E-Cadherin/beta-Catenin-based Adherens Junctions, Molecular Biology of the Cell, vol.18, issue.6, pp.2313-2321, 2007. ,
DOI : 10.1091/mbc.E06-11-1040
Bile Salt Transporters: Molecular Characterization, Function, and Regulation, Physiological Reviews, vol.83, issue.2, pp.633-671, 2003. ,
DOI : 10.1152/physrev.00027.2002
Bile canalicular contraction is coincident with reorganization of pericanalicular filaments and co-localization of actin and myosin-II., Journal of Histochemistry & Cytochemistry, vol.41, issue.3, 1993. ,
DOI : 10.1177/41.3.7679126
The structure and organization of the bile canalicular cytoskeleton with special reference to actin and actin-binding proteins, Hepatology, vol.21, pp.1106-1113, 1995. ,
Subcellular distribution of the inositol 1,4,5-trisphosphate receptors: functional relevance and molecular determinants, Biology of the Cell, vol.96, issue.1, 2004. ,
DOI : 10.1016/j.biolcel.2003.11.004
Structural organization of the endoplasmic reticulum, EMBO reports, vol.3, issue.10, pp.944-950, 2002. ,
DOI : 10.1093/embo-reports/kvf202
Intracellular Trafficking of Bile Salt Export Pump (ABCB11) in Polarized Hepatic Cells: Constitutive Cycling between the Canalicular Membrane and rab11-positive Endosomes, Molecular Biology of the Cell, vol.15, issue.7, pp.3485-3496, 2004. ,
DOI : 10.1091/mbc.E03-10-0737
Transporters on Demand: Intracellular Reservoirs and Cycling of Bile Canalicular ABC Transporters, Journal of Biological Chemistry, vol.281, issue.38, pp.27669-27673, 2006. ,
DOI : 10.1074/jbc.R600013200
Transforming growth factor-??1 induces epithelial-to-mesenchymal transition and apoptosis via a cell cycle-dependent mechanism, Oncogene, vol.199, issue.55, pp.7235-7244, 2006. ,
DOI : 10.1038/sj.onc.1209712
New perspectives on mechanisms involved in generating epithelial cell polarity, Physiol. Rev, vol.79, pp.73-98, 1999. ,
The keratin cytoskeleton in liver diseases, The Journal of Pathology, vol.100, issue.4, pp.367-376, 2004. ,
DOI : 10.1002/path.1649
Sphingolipid Transport to the Apical Plasma Membrane Domain in Human Hepatoma Cells Is Controlled by PKC and PKA Activity: A Correlation with Cell Polarity in HepG2 Cells, The Journal of Cell Biology, vol.63, issue.2, pp.307-321, 1997. ,
DOI : 10.1083/jcb.127.2.401
Actin Filaments and Microtubules are Involved in Different Membrane Traffic Pathways That Transport Sphingolipids to the Apical Surface of Polarized HepG2 Cells, Molecular Biology of the Cell, vol.9, issue.7, pp.1939-1949, 1998. ,
DOI : 10.1091/mbc.9.7.1939