B. Strandvik, E. Gronowitz, F. Enlund, T. Martisson, and J. Wahlström, Essential fatty acid deficiency in relation to genotype in patients with cystic fibrosis, The Journal of Pediatrics, vol.139, issue.5, pp.650-655, 2001.
DOI : 10.1067/mpd.2001.118890

S. Freedman, P. Blanco, M. Zaman, J. Shea, M. Ollero et al., Association of Cystic Fibrosis with Abnormalities in Fatty Acid Metabolism, New England Journal of Medicine, vol.350, issue.6, pp.560-569, 2004.
DOI : 10.1056/NEJMoa021218

S. Freedman, M. Katz, E. Parker, M. Laposata, M. Urman et al., A membrane lipid imbalance plays a role in the phenotypic expression of cystic fibrosis in cftr-/- mice, Proceedings of the National Academy of Sciences, vol.96, issue.24, pp.13995-4000, 1999.
DOI : 10.1073/pnas.96.24.13995

B. Bandali, F. Suh, M. Man, S. Clandinin, and M. , The DF508 mutation in the Cystic Fibrosis Transmembrane Conductance Regulator alters control of essential fatty acid utilization in epithelial cells, J Nutr, vol.130, pp.2870-2875, 2000.

B. Strandvik, M. Brönnegerd, H. Gilljam, and J. Carlstedt-duke, Relation between Defective Regulation of Arachidonic Acid Release and Symptoms in Cystic Fibrosis, Scandinavian Journal of Gastroenterology, vol.32, issue.sup143, pp.1-4, 1988.
DOI : 10.1172/JCI112708

M. Craig-schmidt, S. Faircloth, P. Teer, J. Weete, and C. Wu, The essential fatty acid deficient chicken as a model for cystic fibrosis, Am J Clin Nutr, vol.6, pp.1268-75, 1986.

L. Wood, A. Fitzgerald, P. Gibson, D. Cooper, and M. Garg, Increased plasma fatty acid concentrations after respiratory exacerbations are associated with elevated oxidative stress in cystic fibrosis, Am J Clin Nutr, vol.75, pp.668-75, 2002.

P. Paredji, S. Kharitonov, and P. Barnes, Analysis of Expired Air for Oxidation Products, American Journal of Respiratory and Critical Care Medicine, vol.166, issue.supplement_1, pp.31-38, 2002.
DOI : 10.1164/rccm.2206012

W. Henderson, S. Astley, M. Mccready, P. Kushmerick, S. Casey et al., Oral absorption of omega-3 fatty acids in patients with cystic fibrosis who have pancreatic insufficiency and in healthy control subjects, The Journal of Pediatrics, vol.124, issue.3, pp.400-408, 1994.
DOI : 10.1016/S0022-3476(94)70362-0

D. Katz, T. Manner, P. Furst, and J. Askanazi, The use of an intravenous fish oil emulsion enriched with omega-3 fatty acids in patients with cystic fibrosis, Nutrition, vol.12, issue.5, pp.334-343, 1996.
DOI : 10.1016/S0899-9007(96)80056-6

B. Devisia, V. Raia, C. Spano, C. Pavlidis, A. Coruzzo et al., Effect of an 8-month treatment with ?-3 fatty acids in patients with cystic fibrosis, J Parenter Enter Nutr, vol.27, pp.52-59, 2003.

L. Kurlandsky, M. Benning, and M. Phyllis, The absorption and effect of dietary supplementation with omega-3 fatty acids on serum leukotriene B4, in patients with cystic fibrosis, Pediatric Pulmonology, vol.308, issue.4, pp.211-218, 1984.
DOI : 10.1002/ppul.1950180404

A. Panchaud, A. Sauty, Y. Kernen, L. Decosterd, T. Buclin et al., Biological effects of a dietary omega-3 polyunsaturated fatty acids supplementation in cystic fibrosis patients: A randomized, crossover placebo-controlled trial, Clinical Nutrition, vol.25, issue.3, pp.418-445, 2006.
DOI : 10.1016/j.clnu.2005.10.011

G. Investigators, Dietary Supplementation With n-3 Polyunsaturated Fatty Acids and Vitamin E After Myocardial Infarction: Results of the Gissi-Prevenzione Trial, Journal of Cardiopulmonary Rehabilitation, vol.20, issue.2, pp.447-55, 1999.
DOI : 10.1097/00008483-200003000-00011

P. Palozza, E. Sgarlata, C. Luberto, E. Piccioni, M. Anti et al., N-3 fatty acids induce oxidative modifications in human erythrocytes depending on dose and duration of dietary supplementation, Am J Clin Nutr, vol.64, pp.297-304, 1996.

E. Vericel, A. Polette, S. Bacot, C. Calzada, and M. Lagarde, Pro- and antioxidant activities of docosahexaenoic acid on human blood platelets, Journal of Thrombosis and Haemostasis, vol.279, issue.3, pp.566-72, 2003.
DOI : 10.1046/j.1538-7836.2003.00076.x

M. Lagarde, P. Bryon, M. Guichardant, and M. Dechavanne, A simple and efficient method for platelet isolation from their plasma, Thrombosis Research, vol.17, issue.3-4, pp.581-589, 1980.
DOI : 10.1016/0049-3848(80)90098-5

D. Bowyer, W. Leat, A. Howard, and G. Geshon, The determination of the fatty acid composition of serum lipids separated by thin-layer chromatography; and a comparison with column chromatography, Biochimica et Biophysica Acta, vol.70, pp.423-454, 1963.
DOI : 10.1016/0006-3002(63)90772-8

D. Paglia and W. Valentine, Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase, J Lab Clin Med, vol.70, pp.158-69, 1967.

J. Chaudière and D. Gérard, Dosage de l'activité glutathion peroxidase, Biologie des Lipides chez l'Homme. Paris: Editions Médicales Internationales, pp.275-284, 1988.

A. Roveri, M. Maiorino, and F. Ursini, [20] Enzymatic and immunological measurements of soluble and membrane-bound phospholipid-hydroperoxide glutathione peroxidase, Methods Enzymol, vol.233, pp.202-214, 1994.
DOI : 10.1016/S0076-6879(94)33023-9

M. Lagrange-puget, I. Durieu, R. Ecochard, F. Abbas-chorfa, J. Drai et al., Longitudinal study of oxidative status in 312 cystic fibrosis patients in stable state and during bronchial exacerbation, Pediatric Pulmonology, vol.159, issue.1, pp.43-52, 2004.
DOI : 10.1002/ppul.20041

J. Steghens, V. Kappel, A. Riboli, E. Collombel, and C. , Simultaneous measurement of seven carotenoids, retinol and ??-tocopherol in serum by high-performance liquid chromatography, Journal of Chromatography B: Biomedical Sciences and Applications, vol.694, issue.1, pp.71-81, 1997.
DOI : 10.1016/S0378-4347(97)00140-0

J. Steghens, V. Kappel, A. Denis, I. Collombel, and C. , Diaminonaphtalene, a new highly specific regent for HPLC-UV measurement of total and free malondialdehyde in human plasma or serum, Free Radical Biology and Medicine, vol.31, issue.2, pp.242-251, 2001.
DOI : 10.1016/S0891-5849(01)00578-0

K. Arab and J. Steghens, Plasma lipid hydroperoxides measurement by an automated xylenol orange method, Analytical Biochemistry, vol.325, issue.1, pp.158-63, 2004.
DOI : 10.1016/j.ab.2003.10.022

J. Nourooz-zadeh, Ferrous ion oxidation in presence of xylenol orange for detection of lipid hydroperoxides in plasma, Methods Enzymol, vol.300, pp.58-62, 1999.
DOI : 10.1016/S0076-6879(99)00113-5

J. Steghens, F. Flourie, K. Arab, and C. Collombel, Fast liquid chromatography???mass spectrometry glutathione measurement in whole blood: micromolar GSSG is a sample preparation artifact, Journal of Chromatography B, vol.798, issue.2, pp.343-352, 2003.
DOI : 10.1016/j.jchromb.2003.10.007

M. Guichardant, B. Chantegrel, C. Deshayes, A. Doutheau, P. Moliere et al., Specific markers of lipid peroxidation issued from n???3 and n???6 fatty acids, Biochemical Society Transactions, vol.32, issue.1, pp.139-179, 2004.
DOI : 10.1042/bst0320139

URL : https://hal.archives-ouvertes.fr/hal-00015817

G. Wu, Y. Fang, S. Yang, J. Lupton, and N. Turner, Glutathione metabolism and its implications for health, J Nutr, vol.134, pp.489-92, 2004.

D. Lemaitre, E. Vericel, A. Polette, and M. Lagarde, Effects of fatty acids on human platelet glutathione peroxidase: possible role of oxidative stress, Biochemical Pharmacology, vol.53, issue.4, pp.479-86, 1997.
DOI : 10.1016/S0006-2952(96)00734-4

J. Allard, K. Raghdass, E. Mugli, R. Royall, and D. , Lipid peroxidation during n???3 fatty acid and vitamin E supplementation in humans, Lipids, vol.16, issue.5, pp.535-576, 1997.
DOI : 10.1007/s11745-997-0068-2

B. Strandvik, Fatty Acid Metabolism in Cystic Fibrosis, New England Journal of Medicine, vol.350, issue.6, pp.605-612, 2004.
DOI : 10.1056/NEJMe038217