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Polymorphisms in CYP1A1, GSTM1, GSTT1 and lung cancer below the age of 45 years.

Abstract : BACKGROUND: A genetic component of early-onset lung cancer has been suggested. The role of metabolic gene polymorphisms has never been studied in young lung cancer cases. Phase 1 and Phase 2 gene polymorphisms are involved in tobacco carcinogens' metabolism and therefore in lung cancer risk. METHODS: The effect of metabolic gene polymorphisms on lung cancer at young ages was studied by pooling data from the Genetic Susceptibility to Environmental Carcinogens (GSEC) database. All primary lung cancer cases of both sexes who were Caucasian and
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https://www.hal.inserm.fr/inserm-00266872
Contributor : U754 Secretariat <>
Submitted on : Tuesday, April 1, 2008 - 4:15:06 PM
Last modification on : Thursday, August 22, 2019 - 12:10:38 PM

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  • HAL Id : inserm-00266872, version 1
  • PUBMED : 12690010

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Emanuelle Taioli, Laura Gaspari, Simone Benhamou, Paolo Boffetta, Jürgen Brockmoller, et al.. Polymorphisms in CYP1A1, GSTM1, GSTT1 and lung cancer below the age of 45 years.. International Journal of Epidemiology, Oxford University Press (OUP), 2003, 32 (1), pp.60-3. ⟨inserm-00266872⟩

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