Polymorphisms in CYP1A1, GSTM1, GSTT1 and lung cancer below the age of 45 years. - Archive ouverte HAL Access content directly
Journal Articles International Journal of Epidemiology Year : 2003

Polymorphisms in CYP1A1, GSTM1, GSTT1 and lung cancer below the age of 45 years.

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Abstract

BACKGROUND: A genetic component of early-onset lung cancer has been suggested. The role of metabolic gene polymorphisms has never been studied in young lung cancer cases. Phase 1 and Phase 2 gene polymorphisms are involved in tobacco carcinogens' metabolism and therefore in lung cancer risk. METHODS: The effect of metabolic gene polymorphisms on lung cancer at young ages was studied by pooling data from the Genetic Susceptibility to Environmental Carcinogens (GSEC) database. All primary lung cancer cases of both sexes who were Caucasian and
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Dates and versions

inserm-00266872 , version 1 (01-04-2008)

Identifiers

  • HAL Id : inserm-00266872 , version 1
  • PUBMED : 12690010

Cite

Emanuelle Taioli, Laura Gaspari, Simone Benhamou, Paolo Boffetta, Jürgen Brockmoller, et al.. Polymorphisms in CYP1A1, GSTM1, GSTT1 and lung cancer below the age of 45 years.. International Journal of Epidemiology, 2003, 32 (1), pp.60-3. ⟨inserm-00266872⟩

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