Y. Goshima, F. Nakamura, P. Strittmatter, and S. M. Strittmatter, Collapsin-induced growth cone collapse mediated by an intracellular protein related to UNC-33, Nature, vol.376, issue.6540, pp.509-514, 1995.
DOI : 10.1038/376509a0

Y. Suzuki, S. Nakagomi, K. Namikawa, S. Kiryu-seo, N. Inagaki et al., Collapsin response mediator protein-2 accelerates axon regeneration of nerve-injured motor neurons of rat, Journal of Neurochemistry, vol.16, issue.4, pp.1042-1050, 2003.
DOI : 10.1046/j.1471-4159.2003.01920.x

T. Nishimura, Y. Fukata, K. Kato, T. Yamaguchi, Y. Matsuura et al., CRMP-2 regulates polarized Numb-mediated endocytosis for axon growth, Nature Cell Biology, vol.5, issue.9, pp.819-826, 2003.
DOI : 10.1038/ncb1039

T. Yoshimura, Y. Kawano, N. Arimura, S. Kawabata, A. Kibuchi et al., GSK-3?? Regulates Phosphorylation of CRMP-2 and Neuronal Polarity, Cell, vol.120, issue.1, pp.137-149, 2005.
DOI : 10.1016/j.cell.2004.11.012

F. Zhou and C. S. Cohan, How actin filaments and microtubules steer growth cones to their targets, Journal of Neurobiology, vol.157, issue.1, pp.84-91, 2004.
DOI : 10.1002/neu.10278

J. Yuasa-kawada, R. Suzuki, F. Kano, T. Ohkawara, M. Murata et al., Axonal morphogenesis controlled by antagonistic roles of two CRMP subtypes in microtubule organization, European Journal of Neuroscience, vol.382, issue.11, pp.2329-2343, 2003.
DOI : 10.1046/j.1460-9568.2003.02664.x

T. Kimura, N. Arimura, Y. Fukata, H. Watanabe, A. Iwamatsu et al., Tubulin and CRMP-2 complex is transported via Kinesin-1, Journal of Neurochemistry, vol.161, issue.6, pp.1371-1382, 2005.
DOI : 10.1111/j.1471-4159.2005.03063.x

Y. Kawano, T. Yoshimura, D. Tsuboi, S. Kawabata, T. Kaneto-kawano et al., CRMP-2 Is Involved in Kinesin-1-Dependent Transport of the Sra-1/WAVE1 Complex and Axon Formation, Molecular and Cellular Biology, vol.25, issue.22, pp.9920-9935, 2005.
DOI : 10.1128/MCB.25.22.9920-9935.2005

S. Lee, J. H. Kim, C. S. Lee, J. H. Kim, Y. Kim et al., Collapsin Response Mediator Protein-2 Inhibits Neuronal Phospholipase D2 Activity by Direct Interaction, Journal of Biological Chemistry, vol.277, issue.8, pp.6542-6549, 2002.
DOI : 10.1074/jbc.M108047200

M. Brown, T. Jacobs, B. Eickholt, G. Ferrari, M. Teo et al., ??2-Chimaerin, Cyclin-Dependent Kinase 5/p35, and Its Target Collapsin Response Mediator Protein-2 Are Essential Components in Semaphorin 3A-Induced Growth-Cone Collapse, Journal of Neuroscience, vol.24, issue.41, pp.8994-9004, 2004.
DOI : 10.1523/JNEUROSCI.3184-04.2004

A. R. Cole, A. Knebel, N. A. Morrice, L. A. Robertson, A. J. Irving et al., GSK-3 Phosphorylation of the Alzheimer Epitope within Collapsin Response Mediator Proteins Regulates Axon Elongation in Primary Neurons, Journal of Biological Chemistry, vol.279, issue.48, pp.50176-50180, 2004.
DOI : 10.1074/jbc.C400412200

N. Arimura, N. Inagaki, K. Chihara, C. Ménager, N. Nakamura et al., Phosphorylation of Collapsin Response Mediator Protein-2 by Rho-kinase: EVIDENCE FOR TWO SEPARATE SIGNALING PATHWAYS FOR GROWTH CONE COLLAPSE, Journal of Biological Chemistry, vol.275, issue.31, pp.23973-23980, 2000.
DOI : 10.1074/jbc.M001032200

N. Arimura, C. Ménager, Y. Kawano, T. Yoshimura, S. Kawabata et al., Phosphorylation by Rho Kinase Regulates CRMP-2 Activity in Growth Cones, Molecular and Cellular Biology, vol.25, issue.22, pp.9973-9984, 2005.
DOI : 10.1128/MCB.25.22.9973-9984.2005

Y. Gu, N. Hamajima, and Y. Ihara, Neurofibrillary Tangle-Associated Collapsin Response Mediator Protein-2 (CRMP-2) Is Highly Phosphorylated on Thr-509, Ser-518, and Ser-522, Biochemistry, vol.39, issue.15, pp.4267-4275, 2000.
DOI : 10.1021/bi992323h

Y. Uchida, T. Ohshima, Y. Sasaki, H. Suzuki, S. Yanai et al., Semaphorin3A signalling is mediated via sequential Cdk5 and GSK3?? phosphorylation of CRMP2: implication of common phosphorylating mechanism underlying axon guidance and Alzheimer's disease, Genes to Cells, vol.58, issue.2, pp.165-179, 2005.
DOI : 10.1111/j.1365-2443.2005.00827.x

S. Bretin, S. Reibel, E. Charrier, M. Maus-moati, N. Auvergnon et al., Differential expression of CRMP1, CRMP2A, CRMP2B, and CRMP5 in axons or dendrites of distinct neurons in the mouse brain, Journal of Comparative Neurology, vol.17, issue.1, pp.1-17, 2005.
DOI : 10.1002/cne.20465

R. Kowara, Q. Chen, M. Milliken, and B. Chakravarthy, Calpain-mediated truncation of dihydropyrimidinase-like 3 protein (DPYSL3) in response to NMDA and H2O2 toxicity, Journal of Neurochemistry, vol.531, issue.2, pp.466-474, 2005.
DOI : 10.1006/bbrc.2001.6320

M. A. Chung, J. E. Lee, J. Y. Lee, M. J. Ko, S. T. Lee et al., Alteration of collapsin response mediator protein-2 expression in focal ischemic rat brain, NeuroReport, vol.16, issue.15, pp.1647-1653, 2005.
DOI : 10.1097/01.wnr.0000176520.49841.e6

F. H. Kobeissy, A. K. Otten, Z. Zhang, M. C. Liu, N. D. Denslow et al., Novel Differential Neuroproteomics Analysis of Traumatic Brain Injury in Rats, Molecular & Cellular Proteomics, vol.5, issue.10, pp.1887-1898, 2006.
DOI : 10.1074/mcp.M600157-MCP200

S. Bretin, V. Rogemond, P. Marin, M. Maus, Y. Torrens et al., Calpain product of WT-CRMP2 reduces the amount of surface NR2B NMDA receptor subunit, Journal of Neurochemistry, vol.16, issue.4, pp.1252-1265, 2006.
DOI : 10.1016/j.neuro.2004.03.009

T. T. Quach, A. M. Duchemin, V. Rogemond, M. Aguera, J. Honnorat et al., Involvement of collapsin response mediator proteins in the neurite extension induced by neurotrophins in dorsal root ganglion neurons, Molecular and Cellular Neuroscience, vol.25, issue.3, pp.433-443, 2004.
DOI : 10.1016/j.mcn.2003.11.006

A. Shevenko, M. Wilm, O. Vorm, and M. Mann, Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels, Analytical Chemistry, vol.68, issue.5, pp.850-858, 1996.
DOI : 10.1021/ac950914h

D. G. Higgins and D. Sharp, CLUSTAL: a package for performing multiple sequence alignment on a microcomputer, Gene, vol.73, issue.1, pp.237-244, 1988.
DOI : 10.1016/0378-1119(88)90330-7

P. Stenmark, D. Ogg, S. Flodin, A. Flores, T. Kotenyova et al., The structure of human collapsin response mediator protein 2, a regulator of axonal growth, Journal of Neurochemistry, vol.1, issue.4, pp.906-917, 2007.
DOI : 10.1046/j.1460-9568.2003.02664.x

C. Bulliard, R. Zurbriggen, J. Tornare, M. Faty, Z. Dastoor et al., and aldolase C, Biochemical Journal, vol.324, issue.2, pp.555-563, 1997.
DOI : 10.1042/bj3240555

Z. Zhang, A. K. Ottens, S. Sadasivan, F. H. Kobeissy, T. Fang et al., Calpain-Mediated Collapsin Response Mediator Protein-1, -2, And -4 Proteolysis after Neurotoxic And Traumatic Brain Injury, Journal of Neurotrauma, vol.24, issue.3, pp.460-472, 2007.
DOI : 10.1089/neu.2006.0078

T. Katano, T. Mabuchi, E. Okuda-ashitaka, N. Inagaki, T. Kinumi et al., Proteomic identification of a novel isoform of collapsin response mediator protein-2 in spinal nerves peripheral to dorsal root ganglia, PROTEOMICS, vol.95, issue.22, pp.6085-6094, 2006.
DOI : 10.1002/pmic.200600300

V. Rosslenbroich, L. Dai, S. L. Baader, A. A. Noegel, V. Gieselmann et al., Collapsin response mediator protein-4 regulates F-actin bundling, Experimental Cell Research, vol.310, issue.2, pp.434-444, 2005.
DOI : 10.1016/j.yexcr.2005.08.005

P. Vincent, Y. Collette, R. Marignier, C. Vuaillat, V. Rogemond et al., A Role for the Neuronal Protein Collapsin Response Mediator Protein 2 in T Lymphocyte Polarization and Migration, The Journal of Immunology, vol.175, issue.11, pp.7650-7660, 2005.
DOI : 10.4049/jimmunol.175.11.7650

C. G. Tahimic, N. Tomimatsu, R. Nishigaki, A. Fukuhara, T. Toda et al., Evidence for a role of Collapsin response mediator protein-2 in signaling pathways that regulate the proliferation of non-neuronal cells, Biochemical and Biophysical Research Communications, vol.340, issue.4, pp.1244-1250, 2006.
DOI : 10.1016/j.bbrc.2005.12.132

K. Weis, Nucleocytoplasmic transport: cargo trafficking across the border, Current Opinion in Cell Biology, vol.14, issue.3, pp.328-335, 2002.
DOI : 10.1016/S0955-0674(02)00337-X

C. Dingwall and R. A. Laskey, Nuclear targeting sequences ??? a consensus?, Trends in Biochemical Sciences, vol.16, pp.478-481, 1991.
DOI : 10.1016/0968-0004(91)90184-W

K. J. Bradley, M. R. Bow, S. E. Williams, B. N. Ahmad, C. J. Partridge et al., Parafibromin is a nuclear protein with a functional monopartite nuclear localization signal, Oncogene, vol.13, issue.8, pp.1213-1221, 2007.
DOI : 10.1038/sj.onc.1209893

M. R. Fontes, T. Teh, and B. Kobe, Structural basis of recognition of monopartite and bipartite nuclear localization sequences by mammalian importin-??11Edited by K. Nagai, Journal of Molecular Biology, vol.297, issue.5, pp.1183-1194, 2000.
DOI : 10.1006/jmbi.2000.3642

J. Liu and R. B. , NORSp: predictions of long regions without regular secondary structure, Nucleic Acids Research, vol.31, issue.13, pp.3833-3835, 2003.
DOI : 10.1093/nar/gkg515

P. Tompa, The interplay between structure and function in intrinsically unstructured proteins, FEBS Letters, vol.293, issue.102, pp.3346-3354, 2005.
DOI : 10.1016/j.febslet.2005.03.072