Skip to Main content Skip to Navigation
Journal articles

The design and assessment of prospective randomised, controlled trials in orthopaedic surgery.

Abstract : Randomised controlled trials represent the gold standard in the evaluation of outcome of treatment. They are needed because differences between treatment effects have been minimised and observational studies may give a biased estimation of the outcome. However, conducting this kind of trial is challenging. Several methodological issues, including patient or surgeon preference, blinding, surgical standardisation, as well as external validity, have to be addressed in order to lower the risk of bias. Specific tools have been developed in order to take into account the specificity of evaluation of the literature on non-pharmacological intervention. A better knowledge of methodological issues will allow the orthopaedic surgeon to conduct more appropriate studies and to better appraise the limits of his intervention.
Document type :
Journal articles
Complete list of metadatas

https://www.hal.inserm.fr/inserm-00196578
Contributor : Catherine Gillet <>
Submitted on : Thursday, December 13, 2007 - 10:03:15 AM
Last modification on : Wednesday, August 19, 2020 - 11:17:03 AM
Long-term archiving on: : Friday, November 25, 2016 - 7:36:47 PM

Files

 Restricted access
To satisfy the distribution rights of the publisher, the document is embargoed until : jamais

Please log in to resquest access to the document

Identifiers

Collections

Citation

Isabelle Boutron, Philippe Ravaud, Rémy Nizard. The design and assessment of prospective randomised, controlled trials in orthopaedic surgery.. Journal of Bone and Joint Surgery, British Volume, British Editorial Society of Bone and Joint Surgery, 2007, 89 (7), pp.858-63. ⟨10.1302/0301-620X.89B7.19440⟩. ⟨inserm-00196578⟩

Share

Metrics

Record views

252