Growth Factor Receptor Tyrosine Kinases, Annual Review of Biochemistry, vol.57, issue.1, pp.443-78, 1988. ,
DOI : 10.1146/annurev.bi.57.070188.002303
ERBB receptors and cancer: the complexity of targeted inhibitors ,
NEW EMBO MEMBERS' REVIEW: The ErbB signaling network: receptor heterodimerization in development and cancer, The EMBO Journal, vol.19, issue.13, pp.3159-67, 2000. ,
DOI : 10.1093/emboj/19.13.3159
Cetuximab Shows Activity in Colorectal Cancer Patients With Tumors That Do Not Express the Epidermal Growth Factor Receptor by Immunohistochemistry, Journal of Clinical Oncology, vol.23, issue.9, pp.1803-1813, 2005. ,
DOI : 10.1200/JCO.2005.08.037
Relationship of Epidermal Growth Factor Receptor Expression to ErbB-2 Signaling Activity and Prognosis in Breast Cancer Patients, Journal of Clinical Oncology, vol.23, issue.6 ,
DOI : 10.1200/JCO.2005.09.055
Endocytosis Deficiency of Epidermal Growth Factor (EGF) Receptor-ErbB2 Heterodimers in Response to EGF Stimulation, Molecular Biology of the Cell, vol.10, issue.5, pp.1621-1657, 1999. ,
DOI : 10.1091/mbc.10.5.1621
All ErbB receptors other than the epidermal growth factor receptor are endocytosis impaired, J Biol Chem, vol.271, pp.5251-5258, 1996. ,
EGF???ERBB signalling: towards the systems level, Nature Reviews Molecular Cell Biology, vol.96, issue.7, pp.505-521, 2006. ,
DOI : 10.1038/nrm1962
Strategies for optimizing combinations of molecularly targeted anticancer agents, Nature Reviews Drug Discovery, vol.22, issue.8, pp.649-59, 2006. ,
DOI : 10.1038/nrd2089
Epidermal growth factor receptor (HER1) tyrosine kinase inhibitor ZD1839 (Iressa) inhibits HER2/neu (erbB2)-overexpressing breast cancer cells in vitro and in vivo, Cancer Res, vol.61, pp.8887-95, 2001. ,
A Phase II Trial with Trastuzumab and Pertuzumab in Patients with HER2-Overexpressed Locally Advanced and Metastatic Breast Cancer, Clinical Breast Cancer, vol.6, issue.6, pp.535-544, 2006. ,
DOI : 10.3816/CBC.2006.n.009
In vivo Therapeutic Synergism of Anti-Epidermal Growth Factor Receptor and Anti-HER2 Monoclonal Antibodies against Pancreatic Carcinomas, Clinical Cancer Research, vol.13, issue.11, pp.3356-62, 2007. ,
DOI : 10.1158/1078-0432.CCR-06-2302