Tumors of the liver and intrahepatic bile ducts In: Atlas of tumor pathology Armed Forces Institute of Pathology, 1958. ,
Focal Nodular Hyperplasia of the Liver, The American Journal of Surgical Pathology, vol.23, issue.12, pp.1441-54, 1999. ,
DOI : 10.1097/00000478-199912000-00001
Modern oral contraceptive use and benign liver tumors: the German Benign Liver Tumor Case-Control Study, The European Journal of Contraception & Reproductive Health Care, vol.20, issue.280, pp.194-200, 1998. ,
DOI : 10.1007/s002689900337
Oral contraceptive intake in women with focal nodular hyperplasia of the liver, The Lancet, vol.352, issue.9141, pp.1679-80, 1998. ,
DOI : 10.1016/S0140-6736(05)61451-1
Oral contraceptives and the risk of focal nodular hyperplasia of the liver: A case-control study, American Journal of Obstetrics and Gynecology, vol.186, issue.2, pp.195-202, 2002. ,
DOI : 10.1067/mob.2002.120277
The pathogenesis of focal nodular hyperplasia of the liver, Journal of Gastroenterology and Hepatology, vol.17, issue.s7, pp.1194-200, 1985. ,
DOI : 10.1186/1476-5926-2-7
Focal nodular hyperplasia of the liver associated with portal vein agenesis: a morphological and immunohistochemical study of one case and review of the literature, Adv Clin Path, vol.3, pp.139-184, 1999. ,
High prevalence of hepatic focal nodular hyperplasia in subjects with hereditary hemorrhagic telangiectasia, Ultrasound in Medicine & Biology, vol.30, issue.9, pp.1089-97, 2004. ,
DOI : 10.1016/j.ultrasmedbio.2004.08.004
Congenital absence of the portal vein associated with focal nodular hyperplasia in the liver in an adult woman, Abdominal Imaging, vol.29, issue.4, pp.455-464, 2004. ,
DOI : 10.1007/s00261-003-0131-x
Diagnosis of focal nodular hyperplasia of the liver by needle biopsy, Human Pathology, vol.36, issue.11, pp.1210-1216, 2005. ,
DOI : 10.1016/j.humpath.2005.08.014
Angioarchitecture and blood circulation in focal nodular hyperplasia of the liver, Journal of Hepatology, vol.29, issue.3, pp.521-7470, 1998. ,
DOI : 10.1016/S0168-8278(98)80067-6
Hemodynamics in focal nodular hyperplasia Multiple focal nodular hyperplasia of the liver associated with vascular malformations of various organs and neoplasia of the brain: a new syndrome Clonal analysis of focal nodular hyperplasia of the liver, J Hepatol Mod Pathol Am J Pathol, vol.312148, issue.15, pp.576-14456, 1989. ,
Hepatocellular carcinoma associated with focal nodular hyperplasia, Virchows Archiv, vol.438, issue.4, pp.408-419, 2001. ,
DOI : 10.1007/s004280000348
Focal nodular hyperplasia with concomitant hepatocellular carcinoma: a case report and clonal analysis Evidence for the polyclonal nature of focal nodular hyperplasia of the liver by the study of X-chromosome inactivation, J Clin Pathol Hepatology, vol.5726, issue.18, pp.556-9891, 1997. ,
Multiple chromosomal abnormalities in human liver (pre)neoplasia, Comparative genomic hybridization. Synchronous occurrence of focal nodular hyperplasia and hepatocellular carcinoma in the same liver is not based on common chromosomal aberrations, pp.1211-8660, 2004. ,
DOI : 10.1016/j.jhep.2003.12.020
Multiple clonal chromosome aberrations in a case of childhood focal nodular hyperplasia of the liver Chromosomal analysis of hepatic adenoma and focal nodular hyperplasia by comparative genomic hybridization, P53 gene and Wnt signaling in benign neoplasms: beta-catenin mutations in hepatic adenoma but not in focal nodular hyperplasia, pp.138-42138, 1995. ,
mutations in rare extracolonic tumors of patients with familial adenomatous polyposis coli, Genes, Chromosomes and Cancer, vol.96, issue.2, pp.93-101, 2004. ,
DOI : 10.1002/gcc.20071
Focal nodular hyperplasia of the liver: composition of the extracellular matrix and expression of cell-cell and cell-matrix adhesion molecules Possible association between benign hepatomas and oral contraceptives, Hum Pathol Lancet, vol.262, issue.27, pp.1114-25926, 1973. ,
Liver-cell adenomas associated with use of oral contraceptives Benign liver tumors: what is their relationship to oral contraceptives?, N Engl J Med Am Surg, vol.29442, pp.470-2744, 1976. ,
Primary liver tumors and oral contraceptives Results of a survey A clinicopathologic study of steroidrelated liver tumors Epidemiology of hepatocellular adenoma. The role of oral contraceptive use, 34. Lesna M, Spencer I, Walker W. Letter: Liver nodules and androgens, pp.2154-2162, 1975. ,
ANDROGENIC-ANABOLIC STEROID THERAPY AND HEPATOCELLULAR CARCINOMA, The Lancet, vol.301, issue.7809, p.934, 1973. ,
DOI : 10.1016/S0140-6736(73)91384-6
Glycogen storage disease I and hepatocellular tumours, European Journal of Pediatrics, vol.142, issue.S1, pp.63-70, 1993. ,
DOI : 10.1007/BF02072092
Hepatic ultrasound findings in the glycogen storage diseases The long-term outcome of patients with glycogen storage diseases, 41. de Parscau L, Guibaud P, Maire I. [Glycogenoses type 1b and 1c], pp.1062-6411, 1988. ,
Glycogen Storage Disease in Adults, Annals of Internal Medicine, vol.120, issue.3, pp.218-244, 1994. ,
DOI : 10.7326/0003-4819-120-3-199402010-00008
Hepatocellular adenomas in glycogen storage disease type I and III: a series of 43 patients and review of the literature Terminology of nodular hepatocellular lesions. International Working Party, J Pediatr Gastroenterol Nutr Hepatology Flejou JF, vol.2422, issue.45, pp.276-9983, 1995. ,
Liver Adenomatosis: Reappraisal, Diagnosis, and Surgical Management, Annals of Surgery, vol.231, issue.1, pp.74-81, 2000. ,
DOI : 10.1097/00000658-200001000-00011
Liver adenomatosis: clinical, histopathologic, and imaging findings in 15 patients Familial liver-cell adenomas and diabetes mellitus, Radiology N Engl J Med, vol.216299, issue.48, pp.395-402239, 1978. ,
Regression of liver cell adenoma. A follow-up study of three consecutive patients after discontinuation of oral contraceptive use Complete regression of hepatocellular adenoma after withdrawal of oral contraceptives, Gastroenterology Dig Dis Sci, vol.8226, pp.775-821045, 1981. ,
Progressive enlargement of an hepatic cell adenoma Regressive liver adenomatosis following androgenic progestin therapy withdrawal: a case report with a 10-year follow-up and a molecular analysis Androgen related primary hepatic tumors in non-Fanconi patients, Gastroenterology Eur J Endocrinol Cancer, vol.7715651, issue.52, pp.1319-25617, 1979. ,
Hepatic tumours during androgen therapy in Fanconi anaemia, European Journal of Pediatrics, vol.29, issue.12, pp.691-694, 1993. ,
DOI : 10.1007/BF01955250
Regression of hepatic adenomas in type Ia glycogen storage disease with dietary therapy, Hepatocellular adenomas associated with anabolic androgenic steroid abuse in bodybuilders Hepatic adenoma and focal nodular hyperplasia: clinical, pathologic, and radiologic features, pp.27-56534, 1981. ,
Effect of pregnancy on liver tumor associated with oral contraceptives The malignant transformation of liver cell adenomas, Obstet Gynecol Arch Surg, vol.51129, issue.59, pp.148-51712, 1978. ,
Transformation of hepatic cell adenoma to hepatocellular carcinoma due to oral contraceptive use Hepatocellular carcinoma coexisting with hepatic adenoma. Incidental discovery after long-term oral contraceptive use, J Surg Oncol Ann Intern Med West J Med, vol.35110155, issue.62, pp.173-9489, 1987. ,
Oral contraceptive-associated liver cell adenoma and hepatocellular carcinoma. Cytomorphology and mechanism of malignant transformation, Cancer, vol.26, issue.2, pp.341-348, 1991. ,
DOI : 10.1002/1097-0142(19910715)68:2<341::AID-CNCR2820680223>3.0.CO;2-Q
Type la glycogenosis associated with hepatocellular carcinoma, Cancer, vol.202, issue.6, pp.1320-1322, 1992. ,
DOI : 10.1002/1097-0142(19920315)69:6<1320::AID-CNCR2820690603>3.0.CO;2-D
Liver cell adenoma: a case report with clonal analysis and literature review Genetics of hepatocellular tumors, Hepatocellular carcinoma in glycogen storage disease type Ia: a case series, pp.153-622125, 2005. ,
Trisomy 1 and 8 occur frequently in hepatocellular carcinoma but not in liver cell adenoma and focal nodular hyperplasia. A fluorescence in situ hybridization study Diagnostic impact of fluorescence in situ hybridization in the differentiation of hepatocellular adenoma and well-differentiated hepatocellular carcinoma, J Pathol Virchows Arch J Mol Diagn, vol.1934273, issue.70, pp.476-82373, 1995. ,
Frequent loss of heterozygosity on 6q at the mannose 6-phosphate/insulin-like growth factor II receptor locus in human hepatocellular tumors INK4a-ARF alterations in liver cell adenoma Cloning of human hepatic nuclear factor 1 (HNF1) and chromosomal localization of its gene in man and mouse Interaction of a liverspecific nuclear factor with the fibrinogen and alpha 1-antitrypsin promoters, Oncogene Gut Genomics Science, vol.10518238, issue.72, pp.1725-9253, 1987. ,
Hepatocyte Nuclear Factor 1 Inactivation Results in Hepatic Dysfunction, Phenylketonuria, and Renal Fanconi Syndrome, Cell, vol.84, issue.4, pp.575-85, 1996. ,
DOI : 10.1016/S0092-8674(00)81033-8
?? Knockout Mouse, Molecular and Cellular Biology, vol.18, issue.5, pp.3059-68, 1998. ,
DOI : 10.1128/MCB.18.5.3059
Hepatocyte nuclear factor-1alpha is an essential regulator of bile acid and plasma cholesterol metabolism Loss of HNF-1alpha function in mice leads to abnormal expression of genes involved in pancreatic islet development and metabolism, Nat Genet Diabetes, vol.2750, issue.78, pp.375-822472, 2001. ,
Regulation of the liver fatty acid-binding protein gene by hepatocyte nuclear factor 1alpha (HNF1alpha) Alterations in fatty acid homeostasis in HNF1alpha-deficient mice Bi-allelic inactivation of TCF1 in hepatic adenomas, J Biol Chem Nat Genet, vol.27532, issue.81, pp.27117-22312, 2000. ,
Genotype-phenotype correlation in hepatocellular adenoma: new classification and relationship with HCC, Hepatology, vol.43, issue.82, pp.515-539, 2006. ,
Hepatocellular adenoma subtype classification using molecular markers and immunohistochemistry Frequent mutations of hepatocyte nuclear factor 1 in colorectal cancer with microsatellite instability, Hepatology Gastroenterology, vol.46124, issue.83, pp.740-81311, 2003. ,
Mutation of TCF1 encoding hepatocyte nuclear factor 1?? in gynecological cancer, Oncogene, vol.23, issue.45, pp.7588-92, 2004. ,
DOI : 10.1038/sj.onc.1207989
The Consensus Coding Sequences of Human Breast and Colorectal Cancers, Science, vol.314, issue.5797, pp.268-74, 2006. ,
DOI : 10.1126/science.1133427
HNF1?? Inactivation Promotes Lipogenesis in Human Hepatocellular Adenoma Independently of SREBP-1 and Carbohydrate-response Element-binding Protein (ChREBP) Activation, Journal of Biological Chemistry, vol.282, issue.19, pp.14437-14483, 2007. ,
DOI : 10.1074/jbc.M610725200
URL : https://hal.archives-ouvertes.fr/inserm-00138278
Activation of the beta-catenin gene in primary hepatocellular carcinomas by somatic alterations involving exon 3, Cancer Res, vol.58, issue.89, pp.2524-2531, 1998. ,
90. Nagafuchi A, Takeichi M. Transmembrane control of cadherin-mediated cell adhesion: a 94 kDa protein functionally associated with a specific region of the cytoplasmic domain of E-cadherin Beta-catenin is temporally regulated during normal liver development, Proc Natl Acad Sci U S A Cell Regul Gastroenterology, vol.951126, pp.8847-5137, 1989. ,
New targets of beta-catenin signaling in the liver are involved in the glutamine metabolism Changes in WNT/beta-catenin pathway during regulated growth in rat liver regeneration Conditional deletion of beta-catenin reveals its role in liver growth and regeneration Two case reports of childhood liver cell adenomas harboring beta-catenin abnormalities, al. Hepatic adenomas: analysis of sex steroid receptor status and the Wnt signaling pathway, pp.759-708293, 2001. ,
Diagnostic and pathogenetic implications of the expression of hepatic transporters in focal lesions occurring in normal liver, The Journal of Pathology, vol.31, issue.4, pp.471-82, 2005. ,
DOI : 10.1002/path.1852
Inflammatory syndrome with liver adenomatosis: the beneficial effects of surgical management, Gut, vol.56, issue.2, pp.307-316, 2007. ,
DOI : 10.1136/gut.2006.0106245
Mutations in the hepatocyte nuclear factor-1?? gene in maturity-onset diabetes of the young (MODY3), Nature, vol.384, issue.6608, pp.455-463, 1996. ,
DOI : 10.1038/384455a0
Familia liver adenomatosis associated with hepatocyte nuclear factor 1?? inactivation1 1The authors thank Leigh Pascoe for critical reading of the manuscript, H??l??ne Blanch?? and Hung Bui of the CEPH/Fondation Jean Dausset for technical help in sequencing, and Drs. A. Saillant, E. Akodjenou, and E. Urvoas (Pediatric and Radiology Units, H??pitaux de Chartres, France) for referring patient B1 to E.J. and for performing liver ultrasound screening in family B., Gastroenterology, vol.125, issue.5, pp.1470-1475, 2003. ,
DOI : 10.1016/j.gastro.2003.07.012
Hepatocyte Nuclear Factor-1?? Gene Inactivation: Cosegregation between Liver Adenomatosis and Diabetes Phenotypes in Two Maturity-Onset Diabetes of the Young (MODY)3 Families, The Journal of Clinical Endocrinology & Metabolism, vol.89, issue.3, pp.1476-80, 2004. ,
DOI : 10.1210/jc.2003-031552
Genetic mutation in hepatic adenoma: Seeing is believing, Journal of Hepatology, vol.45, issue.6, pp.767-776, 2006. ,
DOI : 10.1016/j.jhep.2006.09.002
Association of CYP1B1 Germ Line Mutations with Hepatocyte Nuclear Factor 1??-Mutated Hepatocellular Adenoma, Cancer Research, vol.67, issue.6, pp.2611-2617, 2007. ,
DOI : 10.1158/0008-5472.CAN-06-3947
URL : https://hal.archives-ouvertes.fr/inserm-00138277
Identification of deletion mutations and three new genes at the familial polyposis locus, Cell, vol.66, issue.3, pp.601-614, 1991. ,
DOI : 10.1016/0092-8674(81)90022-2
Identification and characterization of the familial adenomatous polyposis coli gene, Cell, vol.66, issue.3, pp.589-600, 1991. ,
DOI : 10.1016/0092-8674(81)90021-0
Childhood hepatocellular adenoma in familial adenomatous polyposis: Mutations in adenomatous polyposis coli gene and p53, Gastroenterology, vol.112, issue.3, pp.919-941, 1997. ,
DOI : 10.1053/gast.1997.v112.pm9041254