PHMPL: a computer program for hazard estimation using a penalized likelihood method with interval-censored and left-truncated data. - Inserm - Institut national de la santé et de la recherche médicale Accéder directement au contenu
Article Dans Une Revue Computer Methods and Programs in Biomedicine Année : 1999

PHMPL: a computer program for hazard estimation using a penalized likelihood method with interval-censored and left-truncated data.

Résumé

The Cox model is the model of choice when analyzing right-censored and possibly left-truncated survival data. The present paper proposes a program to estimate the hazard function in a proportional hazards model and also to treat more complex observation schemes involving general censored and left-truncated data. The hazard function estimator is defined non-parametrically as the function which maximizes a penalized likelihood, and the solution is approximated using splines. The smoothing parameter is chosen using approximate cross-validation. Confidence bands for the estimator are given. As an illustration, the age-specific incidence of dementia is estimated and one of its risk factors is studied.
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Dates et versions

inserm-00182450 , version 1 (26-10-2007)

Identifiants

  • HAL Id : inserm-00182450 , version 1
  • PUBMED : 10579515

Citer

Pierre Joly, Luc Letenneur, Ahmadou Alioum, Daniel Commenges. PHMPL: a computer program for hazard estimation using a penalized likelihood method with interval-censored and left-truncated data.. Computer Methods and Programs in Biomedicine, 1999, 60 (3), pp.225-31. ⟨inserm-00182450⟩

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