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Increased risk of essential tremor in first-degree relatives of patients with Parkinson's disease.

Abstract : We conducted a historical cohort study of 981 first-degree relatives of 162 patients with Parkinson's disease (PD) and of 838 first-degree relatives of 147 controls representative of the population of Olmsted County, Minnesota. In addition, we studied 2,684 first-degree relatives of 411 patients with PD referred to the Mayo Clinic. Relatives were interviewed and screened for tremor either directly or through a proxy, and those who screened positive were examined or copies of their medical records were obtained to confirm the diagnosis of essential tremor (ET). We also obtained ET information from a medical records-linkage system (family study method). In the population-based sample, the risk of ET was significantly increased for relatives of patients with onset of PD
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https://www.hal.inserm.fr/inserm-00180121
Contributor : Christophe Tzourio <>
Submitted on : Wednesday, October 17, 2007 - 5:00:03 PM
Last modification on : Sunday, December 9, 2018 - 1:25:48 AM
Long-term archiving on: : Friday, November 25, 2016 - 5:49:33 PM

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Walter Rocca, James Bower, J. Eric Ahlskog, Alexis Elbaz, Brandon Grossardt, et al.. Increased risk of essential tremor in first-degree relatives of patients with Parkinson's disease.. Movement Disorders, Wiley, 2007, 22 (11), pp.1607-14. ⟨10.1002/mds.21584⟩. ⟨inserm-00180121⟩

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