H. Araujo, N. Danziger, J. Cordier, J. Glowinski, C. et al., Characterization of PEA-15, a major substrate for protein kinase C (PKC) in astrocytes, J. Biol. Chem, vol.268, pp.5911-5920, 1993.

I. M. Bird, N. A. Hanley, R. A. Word, J. M. Mathis, J. L. Mccarthy et al., Human NCI-H295 adrenocortical carcinoma cells: a model for angiotensin-II-responsive aldosterone secretion, Endocrinology, vol.133, pp.1555-1561, 1993.

A. Brunet, D. Roux, P. Lenormand, S. Dowd, S. Keyse et al., Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry, The EMBO Journal, vol.18, issue.3, 1999.
DOI : 10.1093/emboj/18.3.664

A. Chaudhary, W. G. King, M. D. Mattaliano, J. A. Frost, B. Diaz et al., Phosphatidylinositol 3-kinase regulates Raf1 through Pak phosphorylation of serine 338, Current Biology, vol.10, issue.9, pp.551-554, 2000.
DOI : 10.1016/S0960-9822(00)00475-9

F. L. Chou, J. M. Hill, J. C. Hsieh, J. Pouyssegur, A. Brunet et al., PEA-15 Binding to ERK1/2 MAPKs Is Required for Its Modulation of Integrin Activation, Journal of Biological Chemistry, vol.278, issue.52, pp.52587-52597, 2003.
DOI : 10.1074/jbc.M309322200

URL : https://hal.archives-ouvertes.fr/hal-00322408

G. G. Choudhury, C. Karamitsos, J. Hernandez, A. Gentilini, J. Bardgette et al., PI-3-kinase and MAPK regulate mesangial cell proliferation and migration in response to PDGF, Am. J. Physiol, vol.273, pp.931-938, 1997.

G. Condorelli, G. Vigliotta, A. Cafieri, A. Trencia, P. Andalo et al., PED/PEA-15: an anti-apoptotic molecule that regulates FAS/TNFR1-induced apoptosis, Oncogene, vol.18, issue.31, pp.4409-4415, 1999.
DOI : 10.1038/sj.onc.1202831

N. Danziger, M. Yokoyama, T. Jay, J. Cordier, J. Glowinski et al., Cellular Expression, Developmental Regulation, and Phylogenic Conservation of PEA-15, the Astrocytic Major Phosphoprotein and Protein Kinase C Substrate, Journal of Neurochemistry, vol.64, issue.3, pp.1016-1025, 1995.
DOI : 10.1046/j.1471-4159.1995.64031016.x

C. Dugourd, M. Gervais, P. Corvol, and C. Monnot, Akt Is a Major Downstream Target of PI3-Kinase Involved in Angiotensin II-Induced Proliferation, Hypertension, vol.41, issue.4, pp.882-890, 2003.
DOI : 10.1161/01.HYP.0000060821.62417.35

A. Estelles, C. A. Charlton, and H. M. Blau, The Phosphoprotein Protein PEA-15 Inhibits Fas- but Increases TNF-R1-Mediated Caspase-8 Activity and Apoptosis, Developmental Biology, vol.216, issue.1, pp.16-28, 1999.
DOI : 10.1006/dbio.1999.9510

A. Estelles, M. Yokoyama, F. Nothias, J. D. Vincent, J. Glowinski et al., The major astrocytic phosphoprotein PEA-15 is encoded by two mRNAs conserved on their full length in mouse and human, J. Biol. Chem, vol.271, pp.14800-14806, 1996.

C. Figueroa and A. B. Vojtek, Akt negatively regulates translation of the ternary complex factor Elk-1, Oncogene, vol.22, issue.36, pp.5554-5561, 2003.
DOI : 10.1038/sj.onc.1206496

E. Formstecher, PEA-15 Mediates Cytoplasmic Sequestration of ERK MAP Kinase, Developmental Cell, vol.1, issue.2, pp.239-250, 2001.
DOI : 10.1016/S1534-5807(01)00035-1

URL : https://hal.archives-ouvertes.fr/hal-00122265

I. Galetic, S. M. Maira, M. Andjelkovic, and B. A. Hemmings, Negative Regulation of ERK and Elk by Protein Kinase B Modulates c-fos Transcription, Journal of Biological Chemistry, vol.278, issue.7, pp.4416-4423, 2003.
DOI : 10.1074/jbc.M210578200

M. F. Gaumont-leclerc, U. K. Mukhopadhyay, S. Goumard, and G. Ferbeyre, PEA-15 Is Inhibited by Adenovirus E1A and Plays a Role in ERK Nuclear Export and Ras-induced Senescence, Journal of Biological Chemistry, vol.279, issue.45, pp.46802-46809, 2004.
DOI : 10.1074/jbc.M403893200

K. L. Guan, C. Figueroa, T. R. Brtva, T. Zhu, J. Taylor et al., Negative regulation of the serine/threonine kinase B-Raf by Akt, Journal of Biological Chemistry, vol.275, pp.27354-27359, 2000.
DOI : 10.1074/jbc.M004371200

J. M. Hill, H. Vaidyanathan, J. W. Ramos, M. H. Ginsberg, and M. H. Werner, Recognition of ERK MAP kinase by PEA-15 reveals a common docking site within the death domain and death effector domain, The EMBO Journal, vol.21, issue.23, pp.6494-6504, 2002.
DOI : 10.1093/emboj/cdf641

C. L. Hu, R. G. Cowan, R. M. Harman, and S. M. Quirk, Cell Cycle Progression and Activation of Akt Kinase Are Required for Insulin-Like Growth Factor I-Mediated Suppression of Apoptosis in Granulosa Cells, Molecular Endocrinology, vol.18, issue.2, pp.326-338, 2004.
DOI : 10.1210/me.2003-0178

G. J. Inman, F. J. Nicolas, and C. S. Hill, Nucleocytoplasmic Shuttling of Smads 2, 3, and 4 Permits Sensing of TGF-?? Receptor Activity, Molecular Cell, vol.10, issue.2, pp.283-294, 2002.
DOI : 10.1016/S1097-2765(02)00585-3

S. M. Keyse, Protein phosphatases and the regulation of mitogen-activated protein kinase signalling, Current Opinion in Cell Biology, vol.12, issue.2, pp.186-192, 2000.
DOI : 10.1016/S0955-0674(99)00075-7

D. Kitsberg, E. Formstecher, M. Fauquet, M. Kubes, J. Cordier et al., Knock-out of the neural death effector domain protein PEA-15 demonstrates that its expression protects astrocytes from TNFalpha-induced apoptosis, J. Neurosci, vol.19, pp.8244-8251, 1999.

J. Luo, B. D. Manning, C. , and L. C. , Targeting the PI3K-Akt pathway in human cancer, Cancer Cell, vol.4, issue.4, pp.257-262, 2003.
DOI : 10.1016/S1535-6108(03)00248-4

G. Pearson, F. Robinson, T. Beers-gibson, B. E. Xu, M. Karandikar et al., Mitogen-Activated Protein (MAP) Kinase Pathways: Regulation and Physiological Functions, Endocrine Reviews, vol.22, issue.2, pp.153-183, 2001.
DOI : 10.1210/er.22.2.153

C. Peyssonnaux and A. Eychene, The Raf/MEK/ERK pathway: new concepts of activation, Biology of the Cell, vol.93, issue.1-2, pp.53-62, 2001.
DOI : 10.1016/S0248-4900(01)01125-X

J. W. Ramos, P. E. Hughes, M. W. Renshaw, M. A. Schwartz, E. Formstecher et al., Death Effector Domain Protein PEA-15 Potentiates Ras Activation of Extracellular Signal Receptor-activated Kinase by an Adhesion-independent Mechanism, Molecular Biology of the Cell, vol.11, issue.9, pp.2863-2872, 2000.
DOI : 10.1091/mbc.11.9.2863

J. W. Ramos, T. K. Kojima, P. E. Hughes, C. A. Fenczik, and M. H. Ginsberg, The Death Effector Domain of PEA-15 Is Involved in Its Regulation of Integrin Activation, Journal of Biological Chemistry, vol.273, issue.51, pp.33897-33900, 1998.
DOI : 10.1074/jbc.273.51.33897

H. P. Reusch, S. Zimmermann, M. Schaefer, M. Paul, and K. Moelling, Regulation of Raf by Akt Controls Growth and Differentiation in Vascular Smooth Muscle Cells, Journal of Biological Chemistry, vol.276, issue.36, pp.33630-33637, 2001.
DOI : 10.1074/jbc.M105322200

C. Rommel, B. A. Clarke, S. Zimmermann, L. Nunez, R. Rossman et al., Differentiation Stage-Specific Inhibition of the Raf-MEK-ERK Pathway by Akt, Science, vol.286, issue.5445, pp.1738-1741, 1999.
DOI : 10.1126/science.286.5445.1738

H. Sheng, J. Shao, and R. N. Dubois, Akt/PKB activity is required for Ha-Ras-mediated transformation of intestinal epithelial cells, J. Biol. Chem, vol.276, pp.14498-14504, 2001.

H. Sheng, J. Shao, and R. N. Dubois, K-Ras-mediated increase in cyclooxygenase 2 mRNA stability involves activation of the protein kinase B1, Cancer Res, vol.61, pp.2670-2675, 2001.

G. Stassi, M. Garofalo, M. Zerilli, L. Ricci-vitiani, C. Zanca et al., PED Mediates AKT-Dependent Chemoresistance in Human Breast Cancer Cells, Cancer Research, vol.65, issue.15, pp.6668-6675, 2005.
DOI : 10.1158/0008-5472.CAN-04-4009

J. R. Testa and A. Bellacosa, AKT plays a central role in tumorigenesis, Proc. Natl. Acad. Sci. USA 98, pp.10983-10985, 2001.
DOI : 10.1073/pnas.211430998

B. Teutsch, C. Bihoreau, C. Monnot, K. E. Bernstein, T. J. Murphy et al., A recombinant rat vascular AT1 receptor confers growth properties to angiotensin II in Chinese Hamster Ovary cells, Biochemical and Biophysical Research Communications, vol.187, issue.3, pp.1381-1388, 1992.
DOI : 10.1016/0006-291X(92)90455-T

A. Trencia, Protein Kinase B/Akt Binds and Phosphorylates PED/PEA-15, Stabilizing Its Antiapoptotic Action, Molecular and Cellular Biology, vol.23, issue.13, pp.4511-4521, 2003.
DOI : 10.1128/MCB.23.13.4511-4521.2003

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC164852

X. Zheng and W. B. Bollag, AngII induces transient phospholipase D activity in the H295R glomerulosa cell model, Molecular and Cellular Endocrinology, vol.206, issue.1-2, pp.113-122, 2003.
DOI : 10.1016/S0303-7207(03)00211-9

Q. S. Zhu, L. J. Robinson, V. Roginskaya, C. , and S. J. , G-CSF-induced tyrosine phosphorylation of Gab2 is Lyn kinase dependent and associated with enhanced Akt and differentiative, not proliferative, responses, Blood, vol.103, issue.9, pp.3305-3312, 2004.
DOI : 10.1182/blood-2003-06-1861

S. Zimmermann and K. Moelling, Phosphorylation and regulation of Raf by Akt (protein kinase B). Science286, pp.1741-1744, 1999.