Description of the local protein structure. II. Novel approaches. - Inserm - Institut national de la santé et de la recherche médicale Accéder directement au contenu
Chapitre D'ouvrage Année : 2007

Description of the local protein structure. II. Novel approaches.

Résumé

The repetitive local structures, i.e. the alpha-helices and the beta-sheets have been widely used and analysed. However, they only describe 50% of the residues and sometimes roughly. So, other approaches have led to a new view of 3D protein structures. They are now thought to be composed of a combination of small local structures or fragments, also called prototypes. The complete set of prototypes defines “a structural alphabet.” Different teams have described these local protein structures according to different criteria. The structural alphabets have been used to approximate locally the protein structures, analyze them and also for prediction purposes. In this review, we present them from a historic point of view and focus on the most recent advances.
Fichier sous embargo
Fichier sous embargo
Date de visibilité indéterminée

Dates et versions

inserm-00176668 , version 1 (04-10-2007)

Identifiants

  • HAL Id : inserm-00176668 , version 1
  • PRODINRA : 251232

Citer

Manoj Tyagi, Cristina Benros, Juliette Martin, Alexandre de Brevern. Description of the local protein structure. II. Novel approaches.: structural alphabet. Alexandre G. de Brevern. Recent Advances in Structural Bioinformatics, Research Signpost, Trivandrum, Kerala, India., pp.28-42, 2007. ⟨inserm-00176668⟩
166 Consultations
2 Téléchargements

Partager

Gmail Facebook X LinkedIn More