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The effect of near-UV light on Na-K-ATPase of the rat lens.

Abstract : The influence of in vitro near-UV radiation exposure on the physical state of the rat lens and on its membrane-bound Na-K-ATPase activity was investigated. Lens swelling was correlated to the appearance of opacities and the inactivation of the enzyme. The results show a significant decrease in the Na-K-ATPase activity which may be an early change leading to osmotic type cataracts. The dose-effect curves obtained for cortical and epithelial enzymes were different. Since the data do not follow a monoexponential function, the existence of two forms of Na-K-ATPase in the lens is discussed.
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Contributor : Alicia Torriglia Connect in order to contact the contributor
Submitted on : Monday, October 1, 2007 - 4:38:32 PM
Last modification on : Sunday, June 26, 2022 - 9:42:02 AM


  • HAL Id : inserm-00175913, version 1
  • PUBMED : 2841073



A. Torriglia, S. Zigman. The effect of near-UV light on Na-K-ATPase of the rat lens.. Current Eye Research, Taylor & Francis, 1988, 7 (6), pp.539-48. ⟨inserm-00175913⟩



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