Autophagy and related mechanisms of lysosome-mediated protein degradation, Trends Cell Biol, vol.4, pp.139-143, 1994. ,
THE UBIQUITIN-PROTEASOME PATHWAY AND PATHOGENESIS OF HUMAN DISEASES, Annual Review of Medicine, vol.50, issue.1, pp.57-74, 1999. ,
DOI : 10.1146/annurev.med.50.1.57
Mechanisms of chaperone-mediated autophagy, The International Journal of Biochemistry & Cell Biology, vol.36, issue.12, pp.2435-2444, 2004. ,
DOI : 10.1016/j.biocel.2004.02.013
Autophagy, Trends Cell Biol, vol.14, pp.70-77, 2004. ,
DOI : 10.1016/B978-0-12-394447-4.30054-2
URL : https://hal.archives-ouvertes.fr/hal-01439629
Maturation of Autophagic Vacuoles in Mammalian Cells, Autophagy, vol.1, issue.1, pp.1-10, 2005. ,
DOI : 10.4161/auto.1.1.1270
A Unified Nomenclature for Yeast Autophagy-Related Genes, Developmental Cell, vol.5, issue.4, pp.539-545, 2003. ,
DOI : 10.1016/S1534-5807(03)00296-X
Role of the Apg12 conjugation system in mammalian autophagy, The International Journal of Biochemistry & Cell Biology, vol.35, issue.5, pp.553-561, 2003. ,
DOI : 10.1016/S1357-2725(02)00343-6
Regulation and role of autophagy in mammalian cells, The International Journal of Biochemistry & Cell Biology, vol.36, issue.12, pp.2445-2462, 2004. ,
DOI : 10.1016/j.biocel.2004.02.002
Development by Self-Digestion, Developmental Cell, vol.6, issue.4, pp.463-477, 2004. ,
DOI : 10.1016/S1534-5807(04)00099-1
URL : http://doi.org/10.1016/s1534-5807(04)00099-1
Phosphorylation of ribosomal protein S6 is inhibitory for autophagy in isolated rat hepatocytes, J. Biol. Chem, vol.270, pp.2320-2326, 1995. ,
The role of macroautophagy in the ageing process, anti-ageing intervention and age-associated diseases, The International Journal of Biochemistry & Cell Biology, vol.36, issue.12, pp.2392-2404, 2004. ,
DOI : 10.1016/j.biocel.2004.05.007
Autophagy in metazoans: cell survival in the land of plenty, Nature Reviews Molecular Cell Biology, vol.64, issue.6, pp.439-448, 2005. ,
DOI : 10.1093/emboj/19.21.5720
Autophagy in Health and Disease: A Double-Edged Sword, Science, vol.306, issue.5698, pp.990-995, 2004. ,
DOI : 10.1126/science.1099993
Does Autophagy Contribute To Cell Death?, Autophagy, vol.1, issue.2, pp.10-18, 2005. ,
DOI : 10.4161/auto.1.2.1738
Opinion: Autophagy: dual roles in life and death?, Nature Reviews Molecular Cell Biology, vol.72, issue.6, pp.505-510, 2005. ,
DOI : 10.1038/431031a
Developmental cell death: morphological diversity and multiple mechanisms, Anatomy and Embryology, vol.181, issue.3, pp.195-213, 1990. ,
DOI : 10.1007/BF00174615
Role of mitochondrial permeability transition pores in mitochondrial autophagy, The International Journal of Biochemistry & Cell Biology, vol.36, issue.12, pp.2463-2472, 2004. ,
DOI : 10.1016/j.biocel.2004.04.009
The role of autophagy during the early neonatal starvation period, Nature, vol.16, issue.7020, pp.1032-1036, 2004. ,
DOI : 10.1038/365087a0
In Vivo Analysis of Autophagy in Response to Nutrient Starvation Using Transgenic Mice Expressing a Fluorescent Autophagosome Marker, Molecular Biology of the Cell, vol.15, issue.3, pp.1101-1111, 2004. ,
DOI : 10.1091/mbc.E03-09-0704
Autophagy: a barrier or an adaptive response to cancer, Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, vol.1603, issue.2, pp.113-128, 2003. ,
DOI : 10.1016/S0304-419X(03)00004-0
Inhibition of Macroautophagy Triggers Apoptosis, Molecular and Cellular Biology, vol.25, issue.3, pp.1025-1040, 2005. ,
DOI : 10.1128/MCB.25.3.1025-1040.2005
Growth Factor Regulation of Autophagy and Cell Survival in the Absence of Apoptosis, Cell, vol.120, issue.2, pp.237-248, 2005. ,
DOI : 10.1016/j.cell.2004.11.046
Functions of Lysosomes, Annual Review of Physiology, vol.28, issue.1, pp.435-492, 1966. ,
DOI : 10.1146/annurev.ph.28.030166.002251
Inhibition of hepatocytic autophagy by okadaic acid and other protein phosphatase inhibitors, European Journal of Biochemistry, vol.48, issue.1, pp.113-122, 1993. ,
DOI : 10.1016/0014-5793(92)81418-L
The Phosphatidylinositol 3-Kinase Inhibitors Wortmannin and LY294002 Inhibit Autophagy in Isolated Rat Hepatocytes, European Journal of Biochemistry, vol.267, issue.1-2, pp.240-246, 1997. ,
DOI : 10.1083/jcb.110.6.1923
Distinct Classes of Phosphatidylinositol 3'-Kinases Are Involved in Signaling Pathways That Control Macroautophagy in HT-29 Cells, Journal of Biological Chemistry, vol.275, issue.2, pp.992-998, 2000. ,
DOI : 10.1074/jbc.275.2.992
The Tumor Suppressor PTEN Positively Regulates Macroautophagy by Inhibiting the Phosphatidylinositol 3-Kinase/Protein Kinase B Pathway, Journal of Biological Chemistry, vol.276, issue.38, pp.35243-35246, 2001. ,
DOI : 10.1074/jbc.C100319200
The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation, The EMBO Journal, vol.20, issue.21, pp.5971-5981, 2001. ,
DOI : 10.1093/emboj/20.21.5971
Induction of autophagy and inhibition of tumorigenesis by beclin 1, Nature, vol.402, pp.672-676, 1999. ,
-Golgi network, EMBO reports, vol.11, issue.4, pp.330-335, 2001. ,
DOI : 10.1093/embo-reports/kve061
URL : https://hal.archives-ouvertes.fr/in2p3-01333933
Amino-acid-dependent signal transduction, Biochemical Journal, vol.351, issue.3, pp.545-550, 2000. ,
DOI : 10.1042/bj3510545
Thr2446 Is a Novel Mammalian Target of Rapamycin (mTOR) Phosphorylation Site Regulated by Nutrient Status, Journal of Biological Chemistry, vol.279, issue.16, pp.15719-15722, 2004. ,
DOI : 10.1074/jbc.C300534200
Dysregulation of the TSC-mTOR pathway in human disease, Nature Genetics, vol.96, issue.1, pp.19-24, 2005. ,
DOI : 10.1038/nrc1362
The Tuberous Sclerosis Protein TSC2 Is Not Required for the Regulation of the Mammalian Target of Rapamycin by Amino Acids and Certain Cellular Stresses, Journal of Biological Chemistry, vol.280, issue.19, pp.18717-18727, 2005. ,
DOI : 10.1074/jbc.M414499200
Regulation of starvation-and virus-induced autophagy by the eIF2alpha kinase signaling pathway, Proc. Natl. Acad. Sci. USA, pp.190-195, 2002. ,
TOR signalling in bugs, brain and brawn, Nature Reviews Molecular Cell Biology, vol.294, issue.2, pp.117-126, 2003. ,
DOI : 10.1038/nrm1018
Amino acid signalling and the integration of metabolism, Biochemical and Biophysical Research Communications, vol.313, issue.2, pp.397-403, 2004. ,
DOI : 10.1016/j.bbrc.2003.07.012
Amino Acids and Insulin Control Autophagic Proteolysis through Different Signaling Pathways in Relation to mTOR in Isolated Rat Hepatocytes, Journal of Biological Chemistry, vol.279, issue.9, pp.8452-8459, 2004. ,
DOI : 10.1074/jbc.M306337200
Regulation of targets of mTOR (mammalian target of rapamycin) signalling by intracellular amino acid availability, Biochemical Journal, vol.372, issue.2, pp.555-566, 2003. ,
DOI : 10.1042/bj20021266
Leucine Limitation Induces Autophagy and Activation of Lysosome-dependent Proteolysis in C2C12 Myotubes through a Mammalian Target of Rapamycin-independent Signaling Pathway, Journal of Biological Chemistry, vol.275, issue.38, pp.29900-29906, 2000. ,
DOI : 10.1074/jbc.M003633200
Class III phosphoinositide 3-kinase???Beclin1 complex mediates the amino acid-dependent regulation of autophagy in C2C12 myotubes, Biochemical Journal, vol.376, issue.3, pp.577-586, 2003. ,
DOI : 10.1042/bj20030826
Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR Complex, Science, vol.307, issue.5712, pp.1098-1101, 2005. ,
DOI : 10.1126/science.1106148
Amino Acids Interfere with the ERK1/2-dependent Control of Macroautophagy by Controlling the Activation of Raf-1 in Human Colon Cancer HT-29 Cells, Journal of Biological Chemistry, vol.278, issue.19, pp.16667-16674, 2003. ,
DOI : 10.1074/jbc.M210998200
Involvement of Integrins in Osmosensing and Signaling toward Autophagic Proteolysis in Rat Liver, Journal of Biological Chemistry, vol.278, issue.29, pp.27088-27095, 2003. ,
DOI : 10.1074/jbc.M210699200
Mammalian TOR: A Homeostatic ATP Sensor, Science, vol.294, issue.5544, pp.1102-1105, 2001. ,
DOI : 10.1126/science.1063518
Minireview: The AMP-Activated Protein Kinase Cascade: The Key Sensor of Cellular Energy Status, Endocrinology, vol.144, issue.12, pp.5179-5183, 2003. ,
DOI : 10.1210/en.2003-0982
Antagonistic Controls of Autophagy and Glycogen Accumulation by Snf1p, the Yeast Homolog of AMP-Activated Protein Kinase, and the Cyclin-Dependent Kinase Pho85p, Molecular and Cellular Biology, vol.21, issue.17, pp.5742-5752, 2001. ,
DOI : 10.1128/MCB.21.17.5742-5752.2001
Inhibition of Hepatocytic Autophagy by Adenosine, Aminoimidazole-4-carboxamide Riboside, andN 6-Mercaptopurine Riboside: EVIDENCE FOR INVOLVEMENT OF AMP-ACTIVATED PROTEIN KINASE, Journal of Biological Chemistry, vol.273, issue.37, pp.23758-23763, 1998. ,
DOI : 10.1074/jbc.273.37.23758
Toxin-Induced Tail Phosphorylation of Hepatocellular S6 Kinase: Evidence for a Dual Involvement of the AMP-Activated Protein Kinase in S6 Kinase Regulation, Toxicological Sciences, vol.82, issue.2, pp.628-637, 2004. ,
DOI : 10.1093/toxsci/kfh273
Phosphoinositide 3-kinase accelerates autophagic cell death during glucose deprivation in the rat cardiomyocyte-derived cell line H9c2, Oncogene, vol.22, issue.52, pp.8529-8535, 2003. ,
DOI : 10.1038/sj.onc.1207197
Death by design: apoptosis, necrosis and autophagy, Current Opinion in Cell Biology, vol.16, issue.6, pp.663-669, 2004. ,
DOI : 10.1016/j.ceb.2004.09.011
The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans, Genes & Development, vol.18, issue.24, pp.3004-3009, 2004. ,
DOI : 10.1101/gad.1255404
Constitutively active AMP kinase mutations cause glycogen storage disease mimicking hypertrophic cardiomyopathy, Journal of Clinical Investigation, vol.109, issue.3, pp.357-362, 2002. ,
DOI : 10.1172/JCI0214571
Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity, Nature, vol.15, issue.7005, pp.200-205, 2004. ,
DOI : 10.1038/nature01137
Increased Activation of the Mammalian Target of Rapamycin Pathway in Liver and Skeletal Muscle of Obese Rats: Possible Involvement in Obesity-Linked Insulin Resistance, Endocrinology, vol.146, issue.3, pp.1473-1481, 2005. ,
DOI : 10.1210/en.2004-0921
Autophagy and p70S6 Kinase, Autophagy, vol.1, issue.1, pp.59-61, 2005. ,
DOI : 10.4161/auto.1.1.1536
Role and Regulation of Starvation-Induced Autophagy in the Drosophila Fat Body, Developmental Cell, vol.7, issue.2, pp.167-178, 2004. ,
DOI : 10.1016/j.devcel.2004.07.009
The role of insulin and IGF-1 signaling in longevity, CMLS Cellular and Molecular Life Sciences, vol.62, issue.3, pp.320-343, 2005. ,
DOI : 10.1007/s00018-004-4297-y
Autophagy Genes Are Essential for Dauer Development and Life-Span Extension in C. elegans, Science, vol.301, issue.5638, pp.1387-1391, 2003. ,
DOI : 10.1126/science.1087782
Inhibition of autophagy with 3-methyladenine results in impaired turnover of lysosomes and accumulation of lipofuscin-like material, European Journal of Cell Biology, vol.83, issue.10, pp.583-590, 2004. ,
DOI : 10.1078/0171-9335-00433
Oxidative Stress and Stress-Activated Signaling Pathways: A Unifying Hypothesis of Type 2 Diabetes, Endocrine Reviews, vol.23, issue.5, pp.599-622, 2002. ,
DOI : 10.1210/er.2001-0039
Ganglioside GM3 Participates in the Pathological Conditions of Insulin Resistance, Journal of Biological Chemistry, vol.277, issue.5, pp.3085-3092, 2002. ,
DOI : 10.1074/jbc.M103705200
Ceramide-mediated Macroautophagy Involves Inhibition of Protein Kinase B and Up-regulation of Beclin 1, Journal of Biological Chemistry, vol.279, issue.18, pp.18384-18391, 2004. ,
DOI : 10.1074/jbc.M313561200
Ceramide down-regulates System A amino acid transport and protein synthesis in rat skeletal muscle cells, The FASEB Journal, vol.19, pp.461-463, 2005. ,
DOI : 10.1096/fj.04-2284fje
Mitochondrial Dysfunction in the Elderly: Possible Role in Insulin Resistance, Science, vol.300, issue.5622, pp.1140-1142, 2003. ,
DOI : 10.1126/science.1082889
Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes, Nature Cell Biology, vol.12, issue.12, pp.1221-1228, 2004. ,
DOI : 10.1016/S0092-8674(04)00162-X
Programmed Autophagy in the Drosophila Fat Body Is Induced by Ecdysone through Regulation of the PI3K Pathway, Developmental Cell, vol.7, issue.2, pp.179-192, 2004. ,
DOI : 10.1016/j.devcel.2004.07.005
Active cell death induced by the anti-estrogens tamoxifen and ICI 164 384 in human mammary carcinoma cells (MCF-7) in culture: the role of autophagy, Carcinogenesis, vol.17, issue.8, pp.1595-1607, 1996. ,
DOI : 10.1093/carcin/17.8.1595
Oncogenic Ras triggers cell suicide through the activation of a caspase-independent cell death program in human cancer cells, Oncogene, vol.18, issue.13, pp.2281-2290, 1999. ,
DOI : 10.1038/sj.onc.1202538
Ras is involved in the negative control of autophagy through the class I PI3-kinase, Oncogene, vol.23, issue.22, pp.3898-3904, 2004. ,
DOI : 10.1038/sj.onc.1207539
The regulation of death-associated protein (DAP) kinase in apoptosis, Eur. Cytokine Netw, vol.13, pp.398-400, 2002. ,
DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death, The Journal of Cell Biology, vol.2, issue.3, pp.455-468, 2002. ,
DOI : 10.1016/S0960-9822(01)00100-2
Death-associated Protein (DAP) Kinase Plays a Central Role in Ceramide-induced Apoptosis in Cultured Hippocampal Neurons, Journal of Biological Chemistry, vol.277, issue.3, pp.1957-1961, 2002. ,
DOI : 10.1074/jbc.M104677200
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is required for induction of autophagy during lumen formation in vitro, Proc. Natl. Acad. Sci. USA, pp.3438-3443, 2004. ,
DOI : 10.1073/pnas.2436255100
Selective Inactivation of a Fas-associated Death Domain Protein (FADD)-dependent Apoptosis and Autophagy Pathway in Immortal Epithelial Cells, Molecular Biology of the Cell, vol.16, issue.3, pp.1189-1199, 2005. ,
DOI : 10.1091/mbc.E04-10-0906
Inhibition of autophagy abrogates tumour necrosis factor alpha induced apoptosis in human T-lymphoblastic leukaemic cells, British Journal of Haematology, vol.98, issue.3, pp.673-685, 1997. ,
DOI : 10.1046/j.1365-2141.1997.2623081.x
HSpin1, a transmembrane protein interacting with Bcl-2/Bcl-xL, induces a caspase-independent autophagic cell death, Cell Death and Differentiation, vol.10, issue.7, pp.798-807, 2003. ,
DOI : 10.1038/sj.cdd.4401246
A SAGE Approach to Discovery of Genes Involved in Autophagic Cell Death, Current Biology, vol.13, issue.4, pp.358-363, 2003. ,
DOI : 10.1016/S0960-9822(03)00082-4
Essential Roles of Atg5 and FADD in Autophagic Cell Death: DISSECTION OF AUTOPHAGIC CELL DEATH INTO VACUOLE FORMATION AND CELL DEATH, Journal of Biological Chemistry, vol.280, issue.21, pp.20722-20729, 2005. ,
DOI : 10.1074/jbc.M413934200
Regulation of an ATG7-beclin 1 Program of Autophagic Cell Death by Caspase-8, Science, vol.304, issue.5676, pp.1500-1502, 2004. ,
DOI : 10.1126/science.1096645
Genome-Wide Analyses of Steroid- and Radiation-Triggered Programmed Cell Death in Drosophila, Current Biology, vol.13, issue.4, pp.350-357, 2003. ,
DOI : 10.1016/S0960-9822(03)00085-X
The Immunosuppressant Rapamycin Mimics a Starvation-Like Signal Distinct from Amino Acid and Glucose Deprivation, Molecular and Cellular Biology, vol.22, issue.15, pp.5575-5584, 2002. ,
DOI : 10.1128/MCB.22.15.5575-5584.2002
Dissection of Autophagosome Biogenesis into Distinct Nucleation and Expansion Steps, The Journal of Cell Biology, vol.22, issue.5, pp.1025-1034, 2000. ,
DOI : 10.1128/MCB.18.8.4463
Autophagy Is Activated by Apoptotic Signalling in Sympathetic Neurons: An Alternative Mechanism of Death Execution, Molecular and Cellular Neuroscience, vol.14, issue.3, pp.180-198, 1999. ,
DOI : 10.1006/mcne.1999.0780
Bcl-2 down-regulation causes autophagy in a caspase-independent manner in human leukemic HL60 cells, Cell Death and Differentiation, vol.7, issue.12, pp.1263-1269, 2000. ,
DOI : 10.1038/sj.cdd.4400759
Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein, J. Virol, vol.72, pp.8586-8596, 1998. ,
APOPTOSIS: Mitochondria-the Death Signal Integrators, Science, vol.289, issue.5482, pp.1150-1151, 2000. ,
DOI : 10.1126/science.289.5482.1150
Uth1p Is Involved in the Autophagic Degradation of Mitochondria, Journal of Biological Chemistry, vol.279, issue.37, pp.39068-39074, 2004. ,
DOI : 10.1074/jbc.M406960200