D. Abraham and J. Varga, Scleroderma: from cell and molecular mechanisms to disease models, Trends in Immunology, vol.26, issue.11, pp.587-595, 2005.
DOI : 10.1016/j.it.2005.09.004

A. Allison and E. Eugui, Mycophenolate mofetil and its mechanisms of action, Immunopharmacology, vol.47, issue.2-3, pp.85-118, 2000.
DOI : 10.1016/S0162-3109(00)00188-0

S. Arai and G. Vogelsang, Management of graft-versus-host disease, Blood Reviews, vol.14, issue.4, pp.190-204, 2000.
DOI : 10.1054/blre.2000.0137

C. Badid, M. Vincent, B. Mcgregor, M. Melin, A. Hadj-aissa et al., Mycophenolate mofetil reduces myofibroblast infiltration and collagen III deposition in rat remnant kidney, Kidney International, vol.58, issue.1, pp.51-61, 2000.
DOI : 10.1046/j.1523-1755.2000.00140.x

S. Boast, M. Su, F. Ramirez, M. Sanchez, and E. Avvedimento, Functional analysis of cis-acting DNA sequences controlling transcription of the human type I collagen genes, J Biol Chem, vol.265, pp.13351-13356, 1990.

S. Chen, C. Artlett, S. Jimenez, and J. Varga, Modulation of human ??1(I) procollagen gene activity by interaction with Sp1 and Sp3 transcription factors in vitro, Gene, vol.215, issue.1, pp.101-110, 1998.
DOI : 10.1016/S0378-1119(98)00268-6

G. Ciancio, J. Miller, and T. Gonwa, Review of Major Clinical Trials with Mycophenolate Mofetil in Renal Transplantation, Transplantation, vol.80, issue.Supplement, pp.191-200, 2005.
DOI : 10.1097/01.tp.0000187035.22298.ba

G. Danovitch, Mycophenolate Mofetil: A Decade of Clinical Experience, Transplantation, vol.80, issue.Supplement, pp.272-274, 2005.
DOI : 10.1097/01.tp.0000186381.85393.8a

C. Derk and S. Jimenez, Systemic sclerosis: current views of its pathogenesis, Autoimmunity Reviews, vol.2, issue.4, pp.181-191, 2003.
DOI : 10.1016/S1568-9972(03)00005-3

A. Desmouliere, C. Chaponnier, and G. Gabbiani, Tissue repair, contraction, and the myofibroblast, Wound Repair and Regeneration, vol.108, issue.1, pp.7-12, 2005.
DOI : 10.1111/j.1067-1927.2005.130102.x

B. Eckes, P. Zigrino, D. Kessler, O. Holtkotter, P. Shephard et al., Fibroblast-matrix interactions in wound healing and fibrosis, Matrix Biology, vol.19, issue.4, pp.325-332, 2000.
DOI : 10.1016/S0945-053X(00)00077-9

G. Gabbiani, The myofibroblast in wound healing and fibrocontractive diseases, The Journal of Pathology, vol.157, issue.4, pp.500-503, 2003.
DOI : 10.1002/path.1427

C. Gregory, R. Pratt, P. Huie, R. Shorthouse, V. Dzau et al., Effects of treatment with cyclosporine, FK 506, rapamycin, mycophenolic acid, or deoxyspergualin on vascular muscle proliferation in vitro and in vivo, Transplant Proc, vol.25, pp.770-771, 1993.

F. Grinnell, Fibroblasts, myofibroblasts, and wound contraction, The Journal of Cell Biology, vol.124, issue.4, pp.401-404, 1994.
DOI : 10.1083/jcb.124.4.401
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2119916

A. Hess, Modulation of Graft-versus-Host Disease: Role of Regulatory T Lymphocytes, Biology of Blood and Marrow Transplantation, vol.12, issue.1, pp.13-21, 2006.
DOI : 10.1016/j.bbmt.2005.11.002

B. Hinz, G. Celetta, J. Tomasek, G. Gabbiani, and C. Chaponnier, Alpha-Smooth Muscle Actin Expression Upregulates Fibroblast Contractile Activity, Molecular Biology of the Cell, vol.12, issue.9, pp.2730-2741, 2001.
DOI : 10.1091/mbc.12.9.2730
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC59708

B. Hinz, D. Mastrangelo, C. Iselin, C. Chaponnier, and G. Gabbiani, Mechanical Tension Controls Granulation Tissue Contractile Activity and Myofibroblast Differentiation, The American Journal of Pathology, vol.159, issue.3, pp.1009-1020, 2001.
DOI : 10.1016/S0002-9440(10)61776-2
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1850455

D. Javelaud, J. Laboureau, E. Gabison, F. Verrecchia, and A. Mauviel, Disruption of Basal JNK Activity Differentially Affects Key Fibroblast Functions Important for Wound Healing, Journal of Biological Chemistry, vol.278, issue.27, pp.24624-24628, 2003.
DOI : 10.1074/jbc.M301942200
URL : https://hal.archives-ouvertes.fr/inserm-00147462

J. Kim, S. Sohn, D. Kim, N. Lee, J. Suh et al., Different efficacy of mycophenolate mofetil as salvage treatment for acute and chronic GVHD after allogeneic stem cell transplant, European Journal of Haematology, vol.74, issue.2, pp.56-61, 2004.
DOI : 10.1016/S0149-2918(99)80044-7

M. Krejci, M. Doubek, T. Buchler, Y. Brychtova, J. Vorlicek et al., Mycophenolate mofetil for the treatment of acute and chronic steroid-refractory graft-versus-host disease, Annals of Hematology, vol.72, issue.Suppl 4, pp.681-685, 2005.
DOI : 10.1007/s00277-005-1070-0

A. Leask and D. Abraham, TGF-?? signaling and the fibrotic response, The FASEB Journal, vol.18, issue.7, pp.816-827, 2004.
DOI : 10.1096/fj.03-1273rev

S. Liossis, A. Bounas, and A. Ap, Mycophenolate mofetil as first-line treatment improves clinically evident early scleroderma lung disease, Rheumatology, vol.45, issue.8, pp.1005-1008, 2006.
DOI : 10.1093/rheumatology/kei211
URL : http://rheumatology.oxfordjournals.org/cgi/content/short/45/8/1005

F. Lopez, P. Parker, A. Nademanee, R. Rodriguez, Z. Al-kadhimi et al., Efficacy of mycophenolate mofetil in the treatment of chronic graft-versus-host disease, Biology of Blood and Marrow Transplantation, vol.11, issue.4, pp.307-313, 2005.
DOI : 10.1016/j.bbmt.2005.01.011

T. Manzia, D. Liguori-carino, N. Orlando, G. Toti, L. et al., Use of Mycophenolate Mofetil in Liver Transplantation: A Literature Review, Transplantation Proceedings, vol.37, issue.6, pp.2616-2617, 2005.
DOI : 10.1016/j.transproceed.2005.06.073

T. Mele and P. Halloran, The use of mycophenolate mofetil in transplant recipients, Immunopharmacology, vol.47, issue.2-3, pp.215-245, 2000.
DOI : 10.1016/S0162-3109(00)00190-9

N. Poulalhon, D. Farge, N. Roos, C. Tacheau, C. Neuzillet et al., Modulation of Collagen and MMP-1 Gene Expression in Fibroblasts by the Immunosuppressive Drug Rapamycin: A DIRECT ROLE AS AN ANTIFIBROTIC AGENT?, Journal of Biological Chemistry, vol.281, issue.44, pp.33045-33052, 2006.
DOI : 10.1074/jbc.M606366200
URL : https://hal.archives-ouvertes.fr/inserm-00166115

M. Ruzek, S. Jha, S. Ledbetter, S. Richards, and R. Garman, A modified model of graft-versus-host-induced systemic sclerosis (scleroderma) exhibits all major aspects of the human disease, Arthritis & Rheumatism, vol.92, issue.113, pp.1319-1331, 2004.
DOI : 10.1002/art.20160

R. Shapiro, J. Young, E. Milford, J. Trotter, R. Bustami et al., Immunosuppression: evolution in practice and trends, 1993-2003, American Journal of Transplantation, vol.5, issue.2, pp.874-886, 1993.
DOI : 10.1056/NEJMoa021744

A. Singer and R. Clark, Cutaneous wound healing, N Engl J Med, vol.341, pp.738-746, 1999.

O. Skalli, P. Ropraz, A. Trzeciak, G. Benzonana, D. Gillessen et al., A monoclonal antibody against alpha-smooth muscle actin: a new probe for smooth muscle differentiation, The Journal of Cell Biology, vol.103, issue.6, pp.2787-2796, 1986.
DOI : 10.1083/jcb.103.6.2787

R. Stratton, H. Wilson, and C. Black, Pilot study of anti-thymocyte globulin plus mycophenolate mofetil in recent-onset diffuse scleroderma, Rheumatology, vol.40, issue.1, pp.84-88, 2001.
DOI : 10.1093/rheumatology/40.1.84

J. Uitto and D. Kouba, Cytokine modulation of extracellular matrix gene expression: relevance to fibrotic skin diseases, Journal of Dermatological Science, vol.24, pp.60-69, 2000.
DOI : 10.1016/S0923-1811(00)00143-2

F. Verrecchia and A. Mauviel, Control of connective tissue gene expression by TGF??: Role of smad proteins in fibrosis, Current Rheumatology Reports, vol.116, issue.2, pp.143-149, 2002.
DOI : 10.1007/s11926-002-0010-4
URL : https://hal.archives-ouvertes.fr/inserm-00147404

F. Verrecchia and A. Mauviel, Transforming Growth Factor-?? Signaling Through the Smad Pathway: Role in Extracellular Matrix Gene Expression and Regulation, Journal of Investigative Dermatology, vol.118, issue.2, pp.211-215, 2002.
DOI : 10.1046/j.1523-1747.2002.01641.x

F. Verrecchia, A. Mauviel, and D. Farge, Transforming growth factor-?? signaling through the Smad proteins: Role in systemic sclerosis, Autoimmunity Reviews, vol.5, issue.8, pp.563-569, 2006.
DOI : 10.1016/j.autrev.2006.06.001
URL : https://hal.archives-ouvertes.fr/inserm-00166114

F. Verrecchia, E. Wagner, and A. Mauviel, Distinct involvement of the Jun- N-terminal kinase and NF-kappaB pathways in the repression of the human COL1A2 gene by TNF-alpha, EMBO (Eur Mol Biol Organ) Rep, vol.3, pp.1069-1074, 2002.
URL : https://hal.archives-ouvertes.fr/inserm-00147463

R. Zeiser, R. Marks, H. Bertz, and J. Finke, Immunopathogenesis of acute graft-versus-host disease: implications for novel preventive and therapeutic strategies, Ann Hematol, vol.83, pp.551-565, 2004.