Skip to Main content Skip to Navigation
Journal articles

Hypertension, cognitive decline, and dementia: an epidemiological perspective.

Abstract : Hypertension is a known risk factor for stroke, and thus for vascular dementia. However, recent large observational studies have suggested that high blood pressure may also play a role in Alzheimer's disease. The mechanisms linking hypertension to Alzheimer's disease remain to be elucidated, but white matter lesions seen on cerebral magnetic resonance imaging appear to be a good marker of this association. It is not yet clearly established whether lowering blood pressure reduces the risk of white matter lesions and dementia, so large trials dealing with this question are eagerly awaited. These future trials could confirm the hope that, by lowering blood pressure, we may have a preventive treatment for dementia. This issue is of major importance, as the number of cases of dementia is expected to rise
Document type :
Journal articles
Complete list of metadata

Cited literature [85 references]  Display  Hide  Download
Contributor : Christophe Tzourio Connect in order to contact the contributor
Submitted on : Monday, June 23, 2014 - 2:02:40 PM
Last modification on : Sunday, June 26, 2022 - 5:19:36 AM
Long-term archiving on: : Tuesday, September 23, 2014 - 10:35:35 AM


  • HAL Id : inserm-00150111, version 1
  • PUBMED : 17506226


Christophe Tzourio. Hypertension, cognitive decline, and dementia: an epidemiological perspective.. Dialogues in Clinical Neuroscience, Institut La Conférence Hippocrate – Servier Research Group, 2007, 9 (1), pp.61-70. ⟨inserm-00150111⟩



Record views


Files downloads