Pathogenesis of fibrosis: type 1 collagen and the skin, Journal of Molecular Medicine, vol.76, issue.3-4, pp.266-74, 1998. ,
DOI : 10.1007/s001090050216
Collagens and collagen-related diseases, Annals of Medicine, vol.317, issue.1, pp.7-21, 2001. ,
DOI : 10.1016/S0945-053X(97)90071-8
Regulation of Collagen Gene Expression, Prog Nucleic Acid Res Mol Biol, vol.37, pp.67-106, 1989. ,
DOI : 10.1016/S0079-6603(08)60695-9
Transforming Growth Factor-?? Signaling Through the Smad Pathway: Role in Extracellular Matrix Gene Expression and Regulation, Journal of Investigative Dermatology, vol.118, issue.2, pp.211-216, 2002. ,
DOI : 10.1046/j.1523-1747.2002.01641.x
TGF-?? SIGNAL TRANSDUCTION, Annual Review of Biochemistry, vol.67, issue.1, pp.753-91, 1998. ,
DOI : 10.1146/annurev.biochem.67.1.753
NEW EMBO MEMBERS REVIEW: Transcriptional control by the TGF-beta/Smad signaling system, The EMBO Journal, vol.19, issue.8, pp.1745-54, 2000. ,
DOI : 10.1093/emboj/19.8.1745
SARA, a FYVE Domain Protein that Recruits Smad2 to the TGF?? Receptor, Cell, vol.95, issue.6, pp.779-91, 1998. ,
DOI : 10.1016/S0092-8674(00)81701-8
Importin ?? Mediates Nuclear Translocation of Smad 3, Journal of Biological Chemistry, vol.275, issue.31, pp.23425-23433, 2000. ,
DOI : 10.1074/jbc.C000345200
Transforming Growth Factor-?? Induces Nuclear Import of Smad3 in an Importin-??1 and Ran-dependent Manner, Molecular Biology of the Cell, vol.12, issue.4, pp.1079-91, 2001. ,
DOI : 10.1091/mbc.12.4.1079
Convergence of Transforming Growth Factor- and Vitamin D Signaling Pathways on SMAD Transcriptional Coactivators, Science, vol.283, issue.5406, pp.1317-1338, 1999. ,
DOI : 10.1126/science.283.5406.1317
Synergistic cooperation of TFE3 and Smad proteins in TGF-beta -induced transcription of the plasminogen activator inhibitor-1 gene, Genes & Development, vol.12, issue.19, pp.3084-95, 1998. ,
DOI : 10.1101/gad.12.19.3084
Regulation of the human p21/WAF1/Cip1 promoter in hepatic cells by functional interactions between Sp1 and Smad family members, Proceedings of the National Academy of Sciences, vol.338, issue.6210, pp.6733-6741, 1998. ,
DOI : 10.1038/338039a0
Smads bind directly to the Jun family of AP-1 transcription factors, Proceedings of the National Academy of Sciences, vol.12, issue.14, pp.4844-4853, 1999. ,
DOI : 10.1101/gad.12.14.2153
Smad3/AP-1 interactions control transcriptional responses to TGF-?? in a promoter-specific manner, Oncogene, vol.20, issue.26, pp.3332-3372, 2001. ,
DOI : 10.1038/sj.onc.1204448
Induction of the AP-1 members c-Jun and JunB by TGF-??/Smad suppresses early Smad-driven gene activation, Oncogene, vol.20, issue.18, pp.2205-2216, 2001. ,
DOI : 10.1038/sj.onc.1204347
ALTERATION OF NUCLEOSOME STRUCTURE AS A MECHANISM OF TRANSCRIPTIONAL REGULATION, Annual Review of Biochemistry, vol.67, issue.1, pp.545-79, 1998. ,
DOI : 10.1146/annurev.biochem.67.1.545
Cell Cycle Regulation of the Transcriptional Coactivators p300 and CREB Binding Protein, Biochemical Pharmacology, vol.55, issue.12, pp.1947-54, 1998. ,
DOI : 10.1016/S0006-2952(98)00020-3
The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for Smad3 in TGF-beta -induced transcriptional??activation, Genes & Development, vol.12, issue.14, pp.2153-63, 1998. ,
DOI : 10.1101/gad.12.14.2153
TGF-beta -stimulated cooperation of Smad proteins with the coactivators??CBP/p300, Genes & Development, vol.12, issue.14, pp.2114-2123, 1998. ,
DOI : 10.1101/gad.12.14.2114
Role of p300, a transcriptional coactivator, in signalling of TGF-beta, Genes to Cells, vol.1, issue.9, pp.613-636, 1998. ,
DOI : 10.1038/383168a0
Physical and Functional Interaction of SMADs and p300/CBP, Journal of Biological Chemistry, vol.273, issue.36, pp.22865-22873, 1998. ,
DOI : 10.1074/jbc.273.36.22865
TGF-beta -induced Phosphorylation of Smad3 Regulates Its Interaction with Coactivator p300/CREB-binding Protein, Molecular Biology of the Cell, vol.9, issue.12, pp.3309-3328, 1998. ,
DOI : 10.1091/mbc.9.12.3309
E1A Inhibits Transforming Growth Factor-?? Signaling through Binding to Smad Proteins, Journal of Biological Chemistry, vol.274, issue.40, pp.28716-28739, 1999. ,
DOI : 10.1074/jbc.274.40.28716
c-Ski Acts as a Transcriptional Co-repressor in Transforming Growth Factor-?? Signaling through Interaction with Smads, Journal of Biological Chemistry, vol.274, issue.49, pp.35269-35276, 1999. ,
DOI : 10.1074/jbc.274.49.35269
Negative Feedback Regulation of TGF- Signaling by the SnoN Oncoprotein, Science, vol.286, issue.5440, pp.771-775, 1999. ,
DOI : 10.1126/science.286.5440.771
Multiple Modes of Repression by the Smad Transcriptional Corepressor TGIF, Journal of Biological Chemistry, vol.274, issue.52, pp.37105-37115, 1999. ,
DOI : 10.1074/jbc.274.52.37105
SIP1, a Novel Zinc Finger/Homeodomain Repressor, Interacts with Smad Proteins and Binds to 5'-CACCT Sequences in Candidate Target Genes, Journal of Biological Chemistry, vol.274, issue.29, pp.20489-98, 1999. ,
DOI : 10.1074/jbc.274.29.20489
Role of Ras and Mapks in TGF?? signaling, Cytokine & Growth Factor Reviews, vol.11, issue.1-2, pp.23-35, 2000. ,
DOI : 10.1016/S1359-6101(99)00026-X
Interdependent SMAD and JNK Signaling in Transforming Growth Factor-??-mediated Transcription, Journal of Biological Chemistry, vol.274, issue.52, pp.37413-37433, 1999. ,
DOI : 10.1074/jbc.274.52.37413
Transforming Growth Factor-.BETA. Stimulates Articular Chondrocyte Cell Growth through p44/42 MAP Kinase (ERK) Activation., Endocrine Journal, vol.46, issue.4, pp.545-53, 1999. ,
DOI : 10.1507/endocrj.46.545
TGF-beta induces fibronectin synthesis through a c-Jun N-terminal kinase-dependent, Smad4-independent pathway, The EMBO Journal, vol.18, issue.5, pp.1345-56, 1999. ,
DOI : 10.1093/emboj/18.5.1345
Activation of a serine/threonine kinase signaling pathway by transforming growth factor type beta., Proceedings of the National Academy of Sciences, vol.92, issue.26, pp.12110-12114, 1995. ,
DOI : 10.1073/pnas.92.26.12110
Evidence for a Role of Rho-like GTPases and Stress-activated Protein Kinase/c-Jun N-terminal Kinase (SAPK/JNK) in Transforming Growth Factor ??-mediated Signaling, Journal of Biological Chemistry, vol.272, issue.3, pp.1429-1461, 1997. ,
DOI : 10.1074/jbc.272.3.1429
Identification of a Member of the MAPKKK Family as a Potential Mediator of TGF-beta Signal Transduction, Science, vol.270, issue.5244, pp.2008-2019, 1995. ,
DOI : 10.1126/science.270.5244.2008
TAB1: An Activator of the TAK1 MAPKKK in TGF-beta Signal Transduction, Science, vol.272, issue.5265, pp.1179-1187, 1996. ,
DOI : 10.1126/science.272.5265.1179
Involvement of the p38 Mitogen-activated Protein Kinase Pathway in Transforming Growth Factor-??-induced Gene Expression, Journal of Biological Chemistry, vol.274, issue.38, pp.27161-27168, 1999. ,
DOI : 10.1074/jbc.274.38.27161
Role of Transforming Growth Factor-beta Signaling in Cancer, Journal of the National Cancer Institute, vol.92, issue.17, pp.1388-402, 2000. ,
DOI : 10.1093/jnci/92.17.1388
Regional chromosome mapping of human collagen genes alpha 2(I) and alpha 1(I) (COLIA2 and COLIA1), Human Genetics, vol.7, issue.4, pp.304-312, 1985. ,
DOI : 10.1007/BF00291646
Inhibition of Basal and Transforming Growth Factor-beta -induced Stimulation of COL1A1 Transcription by the DNA Intercalators, Mitoxantrone and WP631, in Cultured Human Dermal Fibroblasts, Journal of Biological Chemistry, vol.277, issue.41, pp.38737-38782, 2002. ,
DOI : 10.1074/jbc.M201742200
A nuclear factor 1 binding site mediates the transcriptional activation of a type I collagen promoter by transforming growth factor-??, Cell, vol.52, issue.3, pp.405-419, 1988. ,
DOI : 10.1016/S0092-8674(88)80033-3
An AP-1 Binding Sequence Is Essential for Regulation of the Human 2(I) Collagen (COL1A2) Promoter Activity by Transforming Growth Factor-, Journal of Biological Chemistry, vol.271, issue.6, pp.3272-3280, 1996. ,
DOI : 10.1074/jbc.271.6.3272
Sp1 Is Required for the Early Response of ??2(I) Collagen to Transforming Growth Factor-??1, Journal of Biological Chemistry, vol.272, issue.32, pp.19738-19783, 1997. ,
DOI : 10.1074/jbc.272.32.19738
Stimulation of Type I Collagen Transcription in Human Skin Fibroblasts by TGF-??: Involvement of Smad 3, Journal of Investigative Dermatology, vol.112, issue.1, pp.49-57, 1999. ,
DOI : 10.1046/j.1523-1747.1999.00477.x
Interaction of Smad3 with a proximal smad-binding element of the human ?2(I) procollagen gene promoter required for transcriptional activation by TGF-?, Journal of Cellular Physiology, vol.2, issue.3, pp.381-92, 2000. ,
DOI : 10.1002/(SICI)1097-4652(200006)183:3<381::AID-JCP11>3.0.CO;2-O
Synergistic Cooperation between Sp1 and Smad3/Smad4 Mediates Transforming Growth Factor ??1 Stimulation of ??2(I)-Collagen (COL1A2) Transcription, Journal of Biological Chemistry, vol.275, issue.50, pp.39237-39282, 2000. ,
DOI : 10.1074/jbc.M003339200
Sp1 and Smad Proteins Cooperate to Mediate Transforming Growth Factor-??1-induced ??2(I) Collagen Expression in Human Glomerular Mesangial Cells, Journal of Biological Chemistry, vol.276, issue.10, pp.6983-92, 2001. ,
DOI : 10.1074/jbc.M006442200
Smad-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-?? involves functional cooperation with p300/CBP transcriptional coactivators, Oncogene, vol.19, issue.31, pp.3546-55, 2000. ,
DOI : 10.1038/sj.onc.1203693
Tumor Necrosis Factor, Other Cytokines and Disease, Annual Review of Cell Biology, vol.9, issue.1, pp.317-360, 1993. ,
DOI : 10.1146/annurev.cb.09.110193.001533
Distinct involvement of the Jun-N-terminal kinase and NF-??B pathways in the repression of the human COL1A2 gene by TNF-??, EMBO reports, vol.3, issue.11, pp.1069-74, 2002. ,
DOI : 10.1093/embo-reports/kvf219
Modulation of life and death by the TNF receptor superfamily, Oncogene, vol.17, issue.25, pp.3261-70, 1998. ,
DOI : 10.1038/sj.onc.1202568
Tumor necrosis factor receptor-associated factor (TRAF) 2 and its role in TNF signaling, The International Journal of Biochemistry & Cell Biology, vol.33, issue.1, pp.19-32, 2001. ,
DOI : 10.1016/S1357-2725(00)00064-9
TNF-R1 Signaling: A Beautiful Pathway, Science, vol.296, issue.5573, pp.1634-1639, 2002. ,
DOI : 10.1126/science.1071924
The transcription of human ??1(I) procollagen gene (COL1A1) is suppressed by tumour necrosis factor-?? through proximal short promoter elements: evidence for suppression mechanisms mediated by two nuclear-factorbinding sites, Biochemical Journal, vol.319, issue.3, pp.811-817, 1996. ,
DOI : 10.1042/bj3190811
Tumor necrosis factor?? down-regulates expression of the??1(I) collagen gene in rat hepatic stellate cells through a p20C/EBP??- and C/EBP??-dependent mechanism, Hepatology, vol.162, issue.5, pp.1086-93, 2000. ,
DOI : 10.1053/he.2000.5981
induces the expression of ??1(i) procollagen mRNA by a hydrogen peroxide-C/EBP??-dependent mechanism in rat hepatic stellate cells, Hepatology, vol.89, issue.3, pp.960-70, 1999. ,
DOI : 10.1002/hep.510290346
Tumor Necrosis Factor-?? Inhibits Transforming Growth Factor-?? /Smad Signaling in Human Dermal Fibroblasts via AP-1 Activation, Journal of Biological Chemistry, vol.275, issue.39, pp.30226-30257, 2000. ,
DOI : 10.1074/jbc.M005310200
URL : https://hal.archives-ouvertes.fr/inserm-00150046
Repression of transforming-growth-factor-??-mediated transcription by nuclear factor ??B, Biochemical Journal, vol.348, issue.3, pp.591-597, 2000. ,
DOI : 10.1042/bj3480591
c-Jun Inhibits Transforming Growth Factor beta -mediated Transcription by Repressing Smad3 Transcriptional Activity, Journal of Biological Chemistry, vol.275, issue.37, pp.28858-65, 2000. ,
DOI : 10.1074/jbc.M910358199
A Central Role for the JNK Pathway in Mediating the Antagonistic Activity of Pro-inflammatory Cytokines against Transforming Growth Factor-??-driven SMAD3/4-specific Gene Expression, Journal of Biological Chemistry, vol.278, issue.3, pp.1585-93, 2003. ,
DOI : 10.1074/jbc.M206927200
Control of scarring in adult wounds using antisense transforming growth factor-??1 oligodeoxynucleotides, Immunology and Cell Biology, vol.85, issue.2, pp.144-50, 1996. ,
DOI : 10.1038/icb.1996.19
Inhibition of TGF-??1 expression by antisense oligonucleotides suppressed extracellular matrix accumulation in experimental glomerulonephritis, Kidney International, vol.50, issue.1, pp.148-55, 1996. ,
DOI : 10.1038/ki.1996.297
Interferon-alpha inhibits murine macrophage transforming growth factor-beta mRNA expression, Inflammation, vol.267, issue.3, pp.301-310, 1994. ,
DOI : 10.1007/BF01534271
??-Tocopherol Reduces Proteinuria, Oxidative Stress, and Expression of Transforming Growth Factor ??1 in IgA Nephropathy in the Rat, Molecular Genetics and Metabolism, vol.63, issue.3, pp.224-233, 1998. ,
DOI : 10.1006/mgme.1997.2666
Natural inhibitor of transforming growth factor-?? protects against scarring in experimental kidney disease, Nature, vol.360, issue.6402, pp.361-365, 1992. ,
DOI : 10.1038/360361a0
Chimeric extracellular domain of type II transforming growth factor (TGF)-beta receptor fused to the Fc region of human immunoglobulin as a TGF-beta antagonist, European Journal of Biochemistry, vol.254, issue.3, pp.505-518, 1998. ,
DOI : 10.1046/j.1432-1327.1998.2540505.x
Gene therapy by transforming growth factor-?? receptor-IgG Fc chimera suppressed extracellular matrix accumulation in experimental glomerulonephritis, Kidney International, vol.55, issue.2, pp.465-75, 1999. ,
DOI : 10.1046/j.1523-1755.1999.00275.x
5-Fluorouracil Blocks Transforming Growth Factor-??-Induced ??2 Type I Collagen Gene (COL1A2) Expression in Human Fibroblasts via c-Jun NH2-Terminal Kinase/Activator Protein-1 Activation, Molecular Pharmacology, vol.64, issue.3, pp.707-720, 2003. ,
DOI : 10.1124/mol.64.3.707