R. Akhurst and A. Balmain, Genetic events and the role of TGF?? in epithelial tumour progression, The Journal of Pathology, vol.85, issue.1, pp.82-90, 1999.
DOI : 10.1002/(SICI)1096-9896(199901)187:1<82::AID-PATH248>3.0.CO;2-8

B. Arnulf, A. Villemain, C. Nicot, E. Mordelet, P. Charneau et al., Human T-cell lymphotropic virus oncoprotein Tax represses TGF-beta 1 signaling in human T cells via c-Jun activation: a potential mechanism of HTLV-I leukemogenesis, Blood, vol.100, issue.12, pp.4129-4138, 2002.
DOI : 10.1182/blood-2001-12-0372

M. Arsura, G. Panta, J. Bilyeu, L. Cavin, M. Sovak et al., Transient activation of NF-??B through a TAK1/IKK kinase pathway by TGF-??1 inhibits AP-1/SMAD signaling and apoptosis: implications in liver tumor formation, Oncogene, vol.22, issue.3, pp.412-437, 2003.
DOI : 10.1038/sj.onc.1206132

A. Atfi, S. Djelloul, E. Chastre, R. Davis, and C. Gespach, Evidence for a Role of Rho-like GTPases and Stress-activated Protein Kinase/c-Jun N-terminal Kinase (SAPK/JNK) in Transforming Growth Factor ??-mediated Signaling, Journal of Biological Chemistry, vol.272, issue.3, pp.1429-1461, 1997.
DOI : 10.1074/jbc.272.3.1429

G. Brodin, A. Ahgren, P. Ten-dijke, C. Heldin, and R. Heuchel, Efficient TGF-beta Induction of the Smad7 Gene Requires Cooperation between AP-1, Sp1, and Smad Proteins on the Mouse Smad7 Promoter, Journal of Biological Chemistry, vol.275, issue.37, pp.29023-29053, 2000.
DOI : 10.1074/jbc.M002815200

J. Brown, M. Dichiara, K. Anderson, M. Gimbrone, J. Topper et al., MEKK-1, a Component of the Stress (Stress-activated Protein Kinase/c-Jun N-terminal Kinase) Pathway, Can Selectively Activate Smad2-mediated Transcriptional Activation in Endothelial Cells, Journal of Biological Chemistry, vol.274, issue.13, pp.8797-805, 1999.
DOI : 10.1074/jbc.274.13.8797

M. Calonge and J. Massagué, Smad4/DPC4 Silencing and Hyperactive Ras Jointly Disrupt Transforming Growth Factor-?? Antiproliferative Responses in Colon Cancer Cells, Journal of Biological Chemistry, vol.274, issue.47, pp.33637-33680, 1999.
DOI : 10.1074/jbc.274.47.33637

K. Chung, A. Agarwal, J. Uitto, and A. Mauviel, An AP-1 Binding Sequence Is Essential for Regulation of the Human 2(I) Collagen (COL1A2) Promoter Activity by Transforming Growth Factor-, Journal of Biological Chemistry, vol.271, issue.6, pp.3272-3278, 1996.
DOI : 10.1074/jbc.271.6.3272

R. Davis, Signal Transduction by the JNK Group of MAP Kinases, Cell, vol.103, issue.2, pp.239-252, 2000.
DOI : 10.1016/S0092-8674(00)00116-1

M. De-caestecker, W. Parks, C. Frank, P. Castagnino, D. Bottaro et al., Smad2 transduces common signals from receptor serine-threonine and tyrosine??kinases, Genes & Development, vol.12, issue.11, pp.1587-92, 1998.
DOI : 10.1101/gad.12.11.1587

M. De-caestecker, E. Piek, and A. Roberts, Role of Transforming Growth Factor-beta Signaling in Cancer, Journal of the National Cancer Institute, vol.92, issue.17, pp.1388-402, 2000.
DOI : 10.1093/jnci/92.17.1388

R. Derynck, Y. Zhang, and X. Feng, Transcriptional Activators of TGF-?? Responses: Smads, Cell, vol.95, issue.6, pp.737-777, 1998.
DOI : 10.1016/S0092-8674(00)81696-7

R. Derynck and Y. Zhang, Smad-dependent and Smad-independent pathways in TGF-?? family signalling, Nature, vol.425, issue.6958, pp.577-84, 2003.
DOI : 10.1038/nature02006

D. Guglielmo, G. , L. Roy, C. Goodfellow, A. Wrana et al., Distinct endocytic pathways regulate TGF-?? receptor signalling and turnover, Nature Cell Biology, vol.20, issue.5, pp.410-431, 2003.
DOI : 10.1038/ncb975

S. Dowdy, A. Mariani, and R. Janknecht, HER2/Neu- and TAK1-mediated Up-regulation of the Transforming Growth Factor ?? Inhibitor Smad7 via the ETS Protein ER81, Journal of Biological Chemistry, vol.278, issue.45, pp.44377-84, 2003.
DOI : 10.1074/jbc.M307202200

N. Dumont, A. Bakin, and C. Arteaga, Autocrine Transforming Growth Factor-?? Signaling Mediates Smad-independent Motility in Human Cancer Cells, Journal of Biological Chemistry, vol.278, issue.5, pp.3275-85, 2003.
DOI : 10.1074/jbc.M204623200

T. Ebisawa, M. Fukuchi, G. Murakami, T. Chiba, K. Tanaka et al., Smurf1 Interacts with Transforming Growth Factor-beta Type I Receptor through Smad7 and Induces Receptor Degradation, Journal of Biological Chemistry, vol.276, issue.16, pp.12477-80, 2001.
DOI : 10.1074/jbc.C100008200

S. Edlund, S. Bu, N. Schuster, P. Aspenstrom, R. Heuchel et al., Transforming Growth Factor-beta 1 (TGF-beta )-induced Apoptosis of Prostate Cancer Cells Involves Smad7-dependent Activation of p38 by TGF-beta -activated Kinase 1 and Mitogen-activated Protein Kinase Kinase 3, Molecular Biology of the Cell, vol.14, issue.2, pp.529-573, 2003.
DOI : 10.1091/mbc.02-03-0037

S. Edlund, M. Landstrom, C. Heldin, and P. Aspenstrom, Transforming Growth Factor-beta -induced Mobilization of Actin Cytoskeleton Requires Signaling by Small GTPases Cdc42 and RhoA, Molecular Biology of the Cell, vol.13, issue.3, pp.902-916, 2002.
DOI : 10.1091/mbc.01-08-0398

R. Eferl and E. Wagner, AP-1: a double-edged sword in tumorigenesis, Nature Reviews Cancer, vol.3, issue.11, pp.859-68, 2003.
DOI : 10.1038/nrc1209

M. Engel, M. Mcdonnell, B. Law, and H. Moses, Interdependent SMAD and JNK Signaling in Transforming Growth Factor-??-mediated Transcription, Journal of Biological Chemistry, vol.274, issue.52, pp.37413-37420, 1999.
DOI : 10.1074/jbc.274.52.37413

T. Hai and T. Curran, Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity., Proceedings of the National Academy of Sciences, vol.88, issue.9, pp.3720-3724, 1991.
DOI : 10.1073/pnas.88.9.3720

H. Hanafusa, J. Ninomiya-tsuji, N. Masuyama, M. Nishita, J. Fujisawa et al., Involvement of the p38 Mitogen-activated Protein Kinase Pathway in Transforming Growth Factor-??-induced Gene Expression, Journal of Biological Chemistry, vol.274, issue.38, pp.27161-27168, 1999.
DOI : 10.1074/jbc.274.38.27161

G. Hannon and D. Beach, pl5INK4B is a potentia| effector of TGF-??-induced cell cycle arrest, Nature, vol.371, issue.6494, pp.257-61, 1994.
DOI : 10.1038/371257a0

H. Harlin, S. Reffey, C. Duckett, T. Lindsten, and C. Thompson, Characterization of XIAP-Deficient Mice, Molecular and Cellular Biology, vol.21, issue.10, pp.3604-3612, 2001.
DOI : 10.1128/MCB.21.10.3604-3608.2001

H. Hayashi, S. Abdollah, Y. Qiu, J. Cai, Y. Xu et al., The MAD-Related Protein Smad7 Associates with the TGF?? Receptor and Functions as an Antagonist of TGF?? Signaling, Cell, vol.89, issue.7, pp.1165-73, 1997.
DOI : 10.1016/S0092-8674(00)80303-7

C. Hazzalin and L. Mahadevan, TRANSCRIPTIONMAPK-REGULATED TRANSCRIPTION: A CONTINUOUSLY VARIABLE GENE SWITCH?, Nature Reviews Molecular Cell Biology, vol.3, issue.1, pp.30-40, 2002.
DOI : 10.1038/nrm715

C. Hill, The Smads, The International Journal of Biochemistry & Cell Biology, vol.31, issue.11, pp.1249-54, 1999.
DOI : 10.1016/S1357-2725(99)00093-X

B. Hocevar, T. Brown, and P. Howe, TGF-beta induces fibronectin synthesis through a c-Jun N-terminal kinase-dependent, Smad4-independent pathway, The EMBO Journal, vol.18, issue.5, pp.1345-56, 1999.
DOI : 10.1093/emboj/18.5.1345

P. Hu, X. Shen, D. Huang, Y. Liu, C. Counter et al., The MEK Pathway Is Required for Stimulation of p21WAF1/CIP1 by Transforming Growth Factor-??, Journal of Biological Chemistry, vol.274, issue.50, pp.35381-35388, 1999.
DOI : 10.1074/jbc.274.50.35381

Y. Ip and R. Davis, Signal transduction by the c-Jun N-terminal kinase (JNK) ??? from inflammation to development, Current Opinion in Cell Biology, vol.10, issue.2, pp.205-219, 1998.
DOI : 10.1016/S0955-0674(98)80143-9

S. Itoh, M. Thorikay, M. Kowanetz, A. Moustakas, F. Itoh et al., Elucidation of Smad Requirement in Transforming Growth Factor-beta Type I Receptor-induced Responses, Journal of Biological Chemistry, vol.278, issue.6, pp.3751-61, 2003.
DOI : 10.1074/jbc.M208258200

E. Janda, K. Lehmann, I. Killisch, M. Jechlinger, M. Herzig et al., Ras and TGF?? cooperatively regulate epithelial cell plasticity and metastasis, The Journal of Cell Biology, vol.178, issue.2, pp.299-313, 2002.
DOI : 10.1083/jcb.200109037

D. Javelaud and A. Mauviel, Mammalian transforming growth factor-??s: Smad signaling and physio-pathological roles, The International Journal of Biochemistry & Cell Biology, vol.36, issue.7, pp.1161-1166, 2004.
DOI : 10.1016/S1357-2725(03)00255-3

L. Jonk, S. Itoh, C. Heldin, P. Ten-dijke, and W. Kruijer, Identification and Functional Characterization of a Smad Binding Element (SBE) in the JunB Promoter That Acts as a Transforming Growth Factor-??, Activin, and Bone Morphogenetic Protein-inducible Enhancer, Journal of Biological Chemistry, vol.273, issue.33, pp.21145-52, 1998.
DOI : 10.1074/jbc.273.33.21145

S. Kakonen, K. Selander, J. Chirgwin, J. Yin, S. Burns et al., Transforming Growth Factor-?? Stimulates Parathyroid Hormone-related Protein and Osteolytic Metastases via Smad and Mitogen-activated Protein Kinase Signaling Pathways, Journal of Biological Chemistry, vol.277, issue.27, pp.24571-24579, 2002.
DOI : 10.1074/jbc.M202561200

A. Kamaraju and A. Roberts, Role of Rho/ROCK and p38 MAP Kinase Pathways in Transforming Growth Factor-??-mediated Smad-dependent Growth Inhibition of Human Breast Carcinoma Cells in Vivo, Journal of Biological Chemistry, vol.280, issue.2, pp.1024-1060, 2005.
DOI : 10.1074/jbc.M403960200

M. Karin, Z. Liu, and E. Zandi, AP-1 function and regulation, Current Opinion in Cell Biology, vol.9, issue.2, pp.240-246, 1997.
DOI : 10.1016/S0955-0674(97)80068-3

P. Kavsak, R. Rasmussen, C. Causing, S. Bonni, H. Zhu et al., Smad7 Binds to Smurf2 to Form an E3 Ubiquitin Ligase that Targets the TGF?? Receptor for Degradation, Molecular Cell, vol.6, issue.6, pp.1365-75, 2000.
DOI : 10.1016/S1097-2765(00)00134-9

E. Kim, M. Kim, and M. A. , Transforming growth factor (TGF)-?? in conjunction with H-ras activation promotes malignant progression of MCF10A breast epithelial cells, Cytokine, vol.29, issue.2, pp.84-91, 2005.
DOI : 10.1016/j.cyto.2004.10.001

M. Kretzschmar, J. Doody, I. Timokhina, and J. Massagué, A mechanism of repression of TGFbeta / Smad signaling by oncogenic Ras, Genes & Development, vol.13, issue.7, pp.804-820, 1999.
DOI : 10.1101/gad.13.7.804

K. Lehmann, E. Janda, C. Pierreux, M. Rytomaa, A. Schulze et al., Raf induces TGFbeta production while blocking its apoptotic but not invasive responses: a mechanism leading to increased malignancy in epithelial cells, Genes & Development, vol.14, issue.20, pp.2610-2632, 2000.
DOI : 10.1101/gad.181700

V. Lowes, N. Ip, and Y. Wong, Integration of Signals from Receptor Tyrosine Kinases and G Protein-Coupled Receptors, Neurosignals, vol.11, issue.1, pp.5-19, 2002.
DOI : 10.1159/000057317

M. Lutz and P. Knaus, Integration of the TGF-?? pathway into the cellular signalling network, Cellular Signalling, vol.14, issue.12, p.977, 2002.
DOI : 10.1016/S0898-6568(02)00058-X

A. Mauviel, Y. Chen, W. Dong, C. Evans, and J. Uitto, Transcriptional interactions of transforming growth-factor-?? with pro-inflammatory cytokines, Current Biology, vol.3, issue.12, pp.822-831, 1993.
DOI : 10.1016/0960-9822(93)90216-B
URL : https://hal.archives-ouvertes.fr/inserm-00147456

A. Mazars, F. Lallemand, C. Prunier, J. Marais, N. Ferrand et al., Evidence for a Role of the JNK Cascade in Smad7-mediated Apoptosis, Journal of Biological Chemistry, vol.276, issue.39, pp.36797-36803, 2001.
DOI : 10.1074/jbc.M101672200

K. Miyazono, P. Ten-dijke, and C. Heldin, TGF-?? signaling by Smad proteins, Adv Immunol, vol.75, pp.115-57, 2000.
DOI : 10.1016/S0065-2776(00)75003-6

S. Mori, K. Matsuzaki, K. Yoshida, F. Furukawa, Y. Tahashi et al., TGF-?? and HGF transmit the signals through JNK-dependent Smad2/3 phosphorylation at the linker regions, Oncogene, vol.23, issue.44, pp.7416-7445, 2004.
DOI : 10.1038/sj.onc.1207981

F. Nicolas, D. Bosscher, K. Schmierer, B. Hill, and C. , Analysis of Smad nucleocytoplasmic shuttling in living cells, Journal of Cell Science, vol.117, issue.18, pp.4113-4138, 2004.
DOI : 10.1242/jcs.01289

M. Oft, K. Heider, and H. Beug, TGF?? signaling is necessary for carcinoma cell invasiveness and metastasis, Current Biology, vol.8, issue.23, pp.1243-52, 1998.
DOI : 10.1016/S0960-9822(07)00533-7

M. Oft, J. Peli, C. Rudaz, H. Schwarz, H. Beug et al., TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells., Genes & Development, vol.10, issue.19, pp.2462-77, 1996.
DOI : 10.1101/gad.10.19.2462

T. Ohshima and K. Shimotohno, Transforming Growth Factor-??-mediated Signaling via the p38 MAP Kinase Pathway Activates Smad-dependent Transcription through SUMO-1 Modification of Smad4, Journal of Biological Chemistry, vol.278, issue.51, pp.50833-50875, 2003.
DOI : 10.1074/jbc.M307533200

S. Penheiter, H. Mitchell, N. Garamszegi, M. Edens, D. Jr et al., Internalization-Dependent and -Independent Requirements for Transforming Growth Factor ?? Receptor Signaling via the Smad Pathway, Molecular and Cellular Biology, vol.22, issue.13, pp.4750-4759, 2002.
DOI : 10.1128/MCB.22.13.4750-4759.2002

M. Pessah, C. Prunier, J. Marais, N. Ferrand, A. Mazars et al., c-Jun interacts with the corepressor TG-interacting factor (TGIF) to suppress Smad2 transcriptional activity, Proceedings of the National Academy of Sciences, vol.274, issue.52, pp.6198-203, 2001.
DOI : 10.1074/jbc.274.52.37105

T. Quan, T. He, J. Voorhees, and G. Fisher, Ultraviolet Irradiation Induces Smad7 via Induction of Transcription Factor AP-1 in Human Skin Fibroblasts, Journal of Biological Chemistry, vol.280, issue.9, pp.8079-85, 2005.
DOI : 10.1074/jbc.M409647200

L. Ravanti, L. Hakkinen, H. Larjava, U. Saarialho-kere, M. Foschi et al., Transforming Growth Factor-?? Induces Collagenase-3 Expression by Human Gingival Fibroblasts via p38 Mitogen-activated Protein Kinase, Journal of Biological Chemistry, vol.274, issue.52, pp.37292-300, 1999.
DOI : 10.1074/jbc.274.52.37292

I. Reynisdottir, K. Polyak, A. Iavarone, and J. Massagué, Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta., Genes & Development, vol.9, issue.15, pp.1831-1876, 1995.
DOI : 10.1101/gad.9.15.1831

A. Sanchez-capelo, Dual role for TGF-?1 in apoptosis, Cytokine & Growth Factor Reviews, vol.16, issue.1, pp.15-34, 2005.
DOI : 10.1016/j.cytogfr.2004.11.002

Y. Sano, J. Harada, S. Tashiro, R. Gotoh-mandeville, T. Maekawa et al., ATF-2 Is a Common Nuclear Target of Smad and TAK1 Pathways in Transforming Growth Factor-?? Signaling, Journal of Biological Chemistry, vol.274, issue.13, pp.8949-57, 1999.
DOI : 10.1074/jbc.274.13.8949

E. Shaulian and K. M. , AP-1 in cell proliferation and survival, Oncogene, vol.20, issue.19, pp.2390-400, 2001.
DOI : 10.1038/sj.onc.1204383

E. Shaulian and K. M. , AP-1 as a regulator of cell life and death, Nature Cell Biology, vol.4, issue.5, pp.131-137, 2002.
DOI : 10.1038/ncb0502-e131

W. Shi, C. Sun, B. He, W. Xiong, X. Shi et al., GADD34???PP1c recruited by Smad7 dephosphorylates TGF?? type I receptor, The Journal of Cell Biology, vol.14, issue.2, pp.291-300, 2004.
DOI : 10.1016/S0962-8924(99)01579-2

Y. Shi and J. Massague, Mechanisms of TGF-?? Signaling from Cell Membrane to the Nucleus, Cell, vol.113, issue.6, pp.685-700, 2003.
DOI : 10.1016/S0092-8674(03)00432-X

P. Siegel and J. Massague, Cytostatic and apoptotic actions of TGF-?? in homeostasis and cancer, Nature Reviews Cancer, vol.3, issue.11, pp.807-828, 2003.
DOI : 10.1038/nrc1208

M. Takekawa, K. Tatebayashi, F. Itoh, M. Adachi, K. Imai et al., Smad-dependent GADD45beta expression mediates delayed activation of p38 MAP kinase by TGF-beta, The EMBO Journal, vol.21, issue.23, pp.6473-82, 2002.
DOI : 10.1093/emboj/cdf643

P. Ten-dijke and C. Hill, New insights into TGF-?????Smad signalling, Trends in Biochemical Sciences, vol.29, issue.5, pp.265-73, 2004.
DOI : 10.1016/j.tibs.2004.03.008

F. Tian, S. Byfield, W. Parks, C. Stuelten, D. Nemani et al., Smad-Binding Defective Mutant of Transforming Growth Factor ?? Type I Receptor Enhances Tumorigenesis but Suppresses Metastasis of Breast Cancer Cell Lines, Cancer Research, vol.64, issue.13, pp.4523-4553, 2004.
DOI : 10.1158/0008-5472.CAN-04-0030

R. Treisman, Regulation of transcription by MAP kinase cascades, Current Opinion in Cell Biology, vol.8, issue.2, pp.205-220, 1996.
DOI : 10.1016/S0955-0674(96)80067-6

K. Uchida, H. Suzuki, T. Ohashi, K. Nitta, W. Yumura et al., Involvement of MAP Kinase Cascades in Smad7 Transcriptional Regulation, Biochemical and Biophysical Research Communications, vol.289, issue.2, pp.376-381, 2001.
DOI : 10.1006/bbrc.2001.5984

J. Ventura, N. Kennedy, R. Flavell, and R. Davis, JNK Regulates Autocrine Expression of TGF-??1, Molecular Cell, vol.15, issue.2, pp.269-78, 2004.
DOI : 10.1016/j.molcel.2004.06.007

F. Verrecchia, M. Pessah, A. Atfi, and A. Mauviel, Tumor Necrosis Factor-?? Inhibits Transforming Growth Factor-?? /Smad Signaling in Human Dermal Fibroblasts via AP-1 Activation, Journal of Biological Chemistry, vol.275, issue.39, pp.30226-30257, 2000.
DOI : 10.1074/jbc.M005310200
URL : https://hal.archives-ouvertes.fr/inserm-00150046

F. Verrecchia, C. Tacheau, M. Schorpp-kistner, P. Angel, and A. Mauviel, Induction of the AP-1 members c-Jun and JunB by TGF-??/Smad suppresses early Smad-driven gene activation, Oncogene, vol.20, issue.18, pp.2205-2216, 2001.
DOI : 10.1038/sj.onc.1204347

F. Verrecchia, C. Tacheau, E. Wagner, and A. Mauviel, A Central Role for the JNK Pathway in Mediating the Antagonistic Activity of Pro-inflammatory Cytokines against Transforming Growth Factor-??-driven SMAD3/4-specific Gene Expression, Journal of Biological Chemistry, vol.278, issue.3, pp.1585-93, 2003.
DOI : 10.1074/jbc.M206927200

L. Wakefield and A. Roberts, TGF-???? signaling: positive and negative effects on tumorigenesis, Current Opinion in Genetics & Development, vol.12, issue.1, pp.22-31, 2002.
DOI : 10.1016/S0959-437X(01)00259-3

T. Wang, The 26S proteasome system in the signaling pathways of TGF-BETA superfamily, Frontiers in Bioscience, vol.8, issue.4, pp.1109-1136, 2003.
DOI : 10.2741/1057

C. Wong, E. Rougier-chapman, J. Frederick, M. Datto, N. Liberati et al., Smad3-Smad4 and AP-1 Complexes Synergize in Transcriptional Activation of the c-Jun Promoter by Transforming Growth Factor ??, Molecular and Cellular Biology, vol.19, issue.3, pp.1821-1851, 1999.
DOI : 10.1128/MCB.19.3.1821

Z. Xiao, N. Watson, C. Rodriguez, and H. Lodish, Nucleocytoplasmic Shuttling of Smad1 Conferred by Its Nuclear Localization and Nuclear Export Signals, Journal of Biological Chemistry, vol.276, issue.42, pp.39404-39414, 2001.
DOI : 10.1074/jbc.M103117200

L. Xie, B. Law, A. Chytil, K. Brown, M. Aakre et al., Activation of the Erk Pathway Is Required for TGF-??1-Induced EMT In Vitro, Neoplasia, vol.6, issue.5, pp.603-613, 2004.
DOI : 10.1593/neo.04241

K. Yamaguchi, S. Nagai, J. Ninomiya-tsuji, M. Nishita, K. Tamai et al., XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway, The EMBO Journal, vol.18, issue.1, pp.179-87, 1999.
DOI : 10.1093/emboj/18.1.179

K. Yamaguchi, K. Shirakabe, H. Shibuya, K. Irie, I. Oishi et al., Identification of a Member of the MAPKKK Family as a Potential Mediator of TGF-beta Signal Transduction, Science, vol.270, issue.5244, pp.2008-2019, 1995.
DOI : 10.1126/science.270.5244.2008

X. Yang, R. Khosravi-far, H. Chang, and D. Baltimore, Daxx, a Novel Fas-Binding Protein That Activates JNK and Apoptosis, Cell, vol.89, issue.7, pp.1067-76, 1997.
DOI : 10.1016/S0092-8674(00)80294-9

J. Yin, K. Selander, J. Chirgwin, M. Dallas, B. Grubbs et al., TGF-?? signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development, Journal of Clinical Investigation, vol.103, issue.2, pp.197-206, 1999.
DOI : 10.1172/JCI3523

A. Yonekura, M. Osaki, Y. Hirota, T. Tsukazaki, Y. Miyazaki et al., Transforming Growth Factor-.BETA. Stimulates Articular Chondrocyte Cell Growth through p44/42 MAP Kinase (ERK) Activation., Endocrine Journal, vol.46, issue.4, pp.545-53, 1999.
DOI : 10.1507/endocrj.46.545

J. Yoo, M. Ghiassi, L. Jirmanova, A. Balliet, B. Hoffman et al., Transforming Growth Factor-??-induced Apoptosis Is Mediated by Smad-dependent Expression of GADD45b through p38 Activation, Journal of Biological Chemistry, vol.278, issue.44, pp.43001-43008, 2003.
DOI : 10.1074/jbc.M307869200

K. Yoshida, K. Matsuzaki, S. Mori, Y. Tahashi, H. Yamagata et al., Transforming Growth Factor-?? and Platelet-Derived Growth Factor Signal via c-Jun N-Terminal Kinase-Dependent Smad2/3 Phosphorylation in Rat Hepatic Stellate Cells after Acute Liver Injury, The American Journal of Pathology, vol.166, issue.4, pp.1029-1068, 2005.
DOI : 10.1016/S0002-9440(10)62324-3

L. Yu, M. Hebert, and Y. Zhang, TGF-beta receptor-activated p38 MAP kinase mediates Smad-independent TGF-beta responses, The EMBO Journal, vol.21, issue.14, pp.3749-59, 2002.
DOI : 10.1093/emboj/cdf366
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC126112

Y. Zhang, C. Chang, D. Gehling, A. Hemmati-brivanlou, and R. Derynck, Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase, Proceedings of the National Academy of Sciences, vol.272, issue.24, pp.974-983, 2001.
DOI : 10.1074/jbc.272.24.15085

G. Zhou, S. Lee, Z. Yao, and T. Tan, Hematopoietic Progenitor Kinase 1 Is a Component of Transforming Growth Factor ??-induced c-Jun N-terminal Kinase Signaling Cascade, Journal of Biological Chemistry, vol.274, issue.19, pp.13133-13141, 1999.
DOI : 10.1074/jbc.274.19.13133

C. Zimmerman and R. Padgett, Transforming growth factor ?? signaling mediators and modulators, Gene, vol.249, issue.1-2, pp.17-30, 2000.
DOI : 10.1016/S0378-1119(00)00162-1