B. B. Aggarwal, Signalling pathways of the TNF superfamily: a double-edged sword, Nature Reviews Immunology, vol.3, issue.9, pp.745-756, 2003.
DOI : 10.1038/nri1184

H. Akca, S. Y. Akan, A. Yanikoglu, and O. N. Ozes, Suppression of TNF-?? Mediated Apoptosis by EGF in TNF-?? Sensitive Human Cervical Carcinoma Cell Line, Growth Factors, vol.2, issue.1, pp.31-39, 2003.
DOI : 10.1080/0897719031000115369

D. Armstrong, A. J. Augustin, R. Spengler, A. Jada, T. Nickola et al., Detection of Vascular Endothelial Growth Factor and Tumor Necrosis Factor Alpha in Epiretinal Membranes of Proliferative Diabetic Retinopathy, Proliferative Vitreoretinopathy and Macular Pucker, Ophthalmologica, vol.212, issue.6, pp.410-414, 1998.
DOI : 10.1159/000027378

A. A. Beg and D. Baltimore, An Essential Role for NF-kappa B in Preventing TNF-alpha -Induced Cell Death, Science, vol.274, issue.5288, pp.782-784, 1996.
DOI : 10.1126/science.274.5288.782

E. Berra, M. T. Diaz-meco, J. Lozano, S. Frutos, M. M. Municio et al., Evidence for a role of MEK and MAPK during signal transduction by protein kinase C zeta, EMBO J, vol.14, pp.6157-6163, 1995.

A. M. Butt and H. G. Jenkins, Morphological changes in oligodendrocytes in the intact mouse optic nerve following intravitreal injection of tumour necrosis factor, Journal of Neuroimmunology, vol.51, issue.1, pp.27-33, 1994.
DOI : 10.1016/0165-5728(94)90125-2

P. Crisanti, A. Leon, D. M. Lim, and B. Omri, Aspirin prevention of NMDA-induced neuronal death by direct protein kinase C?? inhibition, Journal of Neurochemistry, vol.22, issue.6, pp.1587-1593, 2005.
DOI : 10.1111/j.1471-4159.2005.03157.x

P. Crisanti, O. Laplace, E. Lecain, L. Jonet, J. C. Jeanny et al., The role of PKC?? in NMDA-induced retinal ganglion cell death: Prevention by aspirin, Apoptosis, vol.95, issue.6, pp.983-991, 2006.
DOI : 10.1007/s10495-006-6750-2

M. T. Diaz-meco, E. Berra, M. M. Municio, L. Sanz, J. Lozano et al., A dominant negative protein kinase C zeta subspecies blocks NF-kappa B activation., Molecular and Cellular Biology, vol.13, issue.8, pp.4770-4775, 1993.
DOI : 10.1128/MCB.13.8.4770

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC360103

M. T. Diaz-meco, M. M. Municio, P. Sanchez, J. Lozano, and J. Moscat, Lambda-interacting protein, a novel protein that specifically interacts with the zinc finger domain of the atypical protein kinase C isotype lambda/iota and stimulates its kinase activity in vitro and in vivo., Molecular and Cellular Biology, vol.16, issue.1, pp.105-114, 1996.
DOI : 10.1128/MCB.16.1.105

P. O. Esteve, E. Chicoine, O. Robledo, F. Aoudjit, A. Descoteaux et al., Protein Kinase C-?? Regulates Transcription of the Matrix Metalloproteinase-9 Gene Induced by IL-1 and TNF-?? in Glioma Cells via NF-??B, Journal of Biological Chemistry, vol.277, issue.38, pp.35150-35155, 2002.
DOI : 10.1074/jbc.M108600200

H. Liang, Protein kinase C-?? mediates retinal degeneration in response to TNF, Journal of Neuroimmunology, vol.183, issue.1-2, pp.104-110, 2007.
DOI : 10.1016/j.jneuroim.2006.11.028

URL : https://hal.archives-ouvertes.fr/inserm-00146368

R. Filomenko, F. Poirson-bichat, C. Billerey, J. P. Belon, C. Garrido et al., Atypical protein kinase C zeta as a target for chemosensitization of tumor cells, Cancer Res, vol.62, pp.1815-1821, 2002.

L. N. Fleisher, J. B. Ferrell, and M. C. Mcgahan, Ocular inflammatory effects of intravitreally injected tumor necrosis factor-alpha and endotoxin, Inflammation, vol.154, issue.3, pp.325-335, 1990.
DOI : 10.1007/BF00915816

V. Fontaine, S. Mohand-said, N. Hanoteau, C. Fuchs, K. Pfizenmaier et al., Neurodegenerative and neuroprotective effects of tumor Necrosis factor (TNF) in retinal ischemia: opposite roles of TNF receptor 1 and TNF receptor 2, J. Neurosci, vol.22, pp.1-7, 2002.

T. Funayama, K. Ishikawa, Y. Ohtake, T. Tanino, D. Kurosaka et al., Variants in Optineurin Gene and Their Association with Tumor Necrosis Factor-?? Polymorphisms in Japanese Patients with Glaucoma, Investigative Opthalmology & Visual Science, vol.45, issue.12, pp.4359-4367, 2004.
DOI : 10.1167/iovs.03-1403

T. Hirai and K. Chida, Protein Kinase Czeta (PKCzeta): Activation Mechanisms and Cellular Functions, Journal of Biochemistry, vol.133, issue.1, pp.1-7, 2003.
DOI : 10.1093/jb/mvg017

URL : http://jb.oxfordjournals.org/cgi/content/short/133/1/1

L. C. Hooper, M. S. Chin, B. Detrick, and J. J. Hooks, Retinal degeneration in experimental coronavirus retinopathy (ECOR) is associated with increased TNF-??, soluble TNFR2 and altered TNF-?? signaling, Journal of Neuroimmunology, vol.166, issue.1-2, pp.65-74, 2005.
DOI : 10.1016/j.jneuroim.2005.05.018

H. G. Jenkins and H. Ikeda, Tumour necrosis factor causes an increase in axonal transport of protein and demyelination in the mouse optic nerve, Journal of the Neurological Sciences, vol.108, issue.1, pp.99-104, 1992.
DOI : 10.1016/0022-510X(92)90194-P

M. Kalai, M. Lamkanfi, G. Denecker, M. Boogmans, S. Lippens et al., Regulation of the expression and processing of caspase-12, The Journal of Cell Biology, vol.51, issue.3, pp.457-467, 2003.
DOI : 10.1016/S0092-8674(00)80943-5

M. Karin and A. Lin, NF-??B at the crossroads of life and death, Nature Immunology, vol.3, issue.3, pp.221-227, 2002.
DOI : 10.1038/ni0302-221

Y. Kitaoka, T. Kumai, Y. Kitaoka, T. T. Lam, Y. Munemasa et al., Nuclear factor-kappa B p65 in NMDA-induced retinal neurotoxicity, Molecular Brain Research, vol.131, issue.1-2, pp.8-16, 2004.
DOI : 10.1016/j.molbrainres.2004.07.021

S. Koponen, K. Kurkinen, K. E. Akerman, P. H. Mochly-rosen, and J. Koistinaho, Prevention of NMDA-induced death of cortical neurons by inhibition of protein kinase C??, Journal of Neurochemistry, vol.96, issue.2, pp.442-452, 2003.
DOI : 10.1046/j.1471-4159.2003.01846.x

H. J. Lin, F. J. Tsai, W. C. Chen, Y. R. Shi, Y. Hsu et al., Association of tumour necrosis factor alpha ???308 gene polymorphism with primary open-angle glaucoma in Chinese, Eye, vol.17, issue.1, pp.31-34, 2003.
DOI : 10.1038/sj.eye.6700227

J. Lozano, E. Berra, M. M. Municio, M. T. Diaz-meco, I. Dominguez et al., Protein kinase C zeta isoform is critical for kappa B-dependent promoter activation by sphingomyelinase, J. Biol. Chem, vol.269, pp.19200-19202, 1994.

M. C. Madigan, A. A. Sadun, N. S. Rao, P. U. Dugel, W. N. Tenhula et al., Tumor necrosis factor-alpha (TNF-??)-induced optic neuropathy in rabbits, Neurological Research, vol.18, issue.2, pp.176-184, 1996.
DOI : 10.1080/01616412.1996.11740399

P. Martin, A. Duran, S. Minguet, M. L. Gaspar, M. T. Diaz-meco et al., Role of zetaPKC in B-cell signaling and function, The EMBO Journal, vol.21, issue.15, pp.4049-4057, 2002.
DOI : 10.1093/emboj/cdf407

G. Muller, M. Ayoub, P. Storz, J. Rennecke, D. Fabbro et al., PKC zeta is a molecular switch in signal transduction of TNFalpha , bifunctionally regulated by ceramide and arachidonic acid, EMBO J, vol.14, pp.1961-1969, 1995.

H. Oh, H. Takagi, C. Takagi, K. Suzuma, A. Otani et al., The potential angiogenic role of macrophages in the formation of choroidal neovascular membranes, Invest. Ophthalmol. Vis. Sci, vol.40, pp.1891-1898, 1999.

A. Rahman, K. N. Anwar, and A. B. Malik, Protein kinase C-zeta mediates TNF-alpha-induced ICAM-1 gene transcription in endothelial cells, Am. J. Physiol., Cell Physiol, vol.279, pp.906-914, 2000.

J. T. Rosenbaum, E. L. Howes-jr, R. M. Rubin, and J. R. Samples, Ocular inflammatory effects of intravitreally-injected tumor necrosis factor, Am. J. Pathol, vol.133, pp.47-53, 1988.

D. M. Rzymkiewicz, T. Tetsuka, D. Daphna-iken, S. Srivastava, and A. R. Morrison, Interleukin-1?? Activates Protein Kinase C?? in Renal Mesangial Cells: POTENTIAL ROLE IN PROSTAGLANDIN E2 UP-REGULATION, Journal of Biological Chemistry, vol.271, issue.29, pp.17241-17246, 1996.
DOI : 10.1074/jbc.271.29.17241

E. Shohami, I. Ginis, and J. M. Hallenbeck, Dual role of tumor necrosis factor alpha in brain injury, Cytokine & Growth Factor Reviews, vol.10, issue.2, pp.119-130, 1999.
DOI : 10.1016/S1359-6101(99)00008-8

L. Smith and J. B. Smith, Lack of Constitutive Activity of the Free Kinase Domain of Protein Kinase C zeta . DEPENDENCE ON TRANSPHOSPHORYLATION OF THE ACTIVATION LOOP, Journal of Biological Chemistry, vol.277, issue.48, pp.45866-45873, 2002.
DOI : 10.1074/jbc.M206420200

G. Tezel and M. B. Wax, Increased production of tumor necrosis factoralpha by glial cells exposed to simulated ischemia or elevated hydrostatic pressure induces apoptosis in cocultured retinal ganglion cells, J. Neurosci, vol.20, pp.8693-8700, 2000.

G. Tezel and X. Yang, Caspase-Independent Component of Retinal Ganglion Cell Death, In Vitro, Investigative Opthalmology & Visual Science, vol.45, issue.11, pp.4049-4059, 2004.
DOI : 10.1167/iovs.04-0490

G. Tezel, L. Y. Li, R. V. Patil, and M. B. Wax, TNF-alpha and TNF-alpha receptor-1 in the retina of normal and glaucomatous eyes, Invest. Ophthalmol. Vis. Sci, vol.42, pp.1787-1794, 2001.

S. Umar, J. H. Sellin, and A. P. Morris, Increased nuclear translocation of catalytically active PKC-zeta during mouse colonocyte hyperproliferation, Am. J. Physiol.: Gasterointest Liver Physiol, vol.279, pp.223-237, 2000.

D. J. Van-antwerp, S. J. Martin, T. Kafri, D. R. Green, and I. M. Verma, Suppression of TNF-alpha -Induced Apoptosis by NF-kappa B, Science, vol.274, issue.5288, pp.787-789, 1996.
DOI : 10.1126/science.274.5288.787

M. B. Wax and G. Tezel, Neurobiology of Glaucomatous Optic Neuropathy: Diverse Cellular Events in Neurodegeneration and Neuroprotection, Molecular Neurobiology, vol.26, issue.1, pp.45-55, 2002.
DOI : 10.1385/MN:26:1:045

X. Yan, Matrix Metalloproteinases and Tumor Necrosis Factor ?? in Glaucomatous Optic Nerve Head, Archives of Ophthalmology, vol.118, issue.5, pp.666-673, 2000.
DOI : 10.1001/archopht.118.5.666

L. Yuan and A. H. Neufeld, Tumor necrosis factor-?: A potentially neurodestructive cytokine produced by glia in the human glaucomatous optic nerve head, Glia, vol.11, issue.1, pp.42-50, 2000.
DOI : 10.1002/1098-1136(200010)32:1<42::AID-GLIA40>3.0.CO;2-3