Skip to Main content Skip to Navigation
Journal articles

Microstructuration of protein matrices by laser-induced photochemistry

Abstract : We report on the laser fabrication of BSA and type I collagen microstructures using Eosin Y or Rose Bengal photo sensitizers. Similar cross-linking results have been obtained by one-photon absorption or two-photon absorption using a green Q-switched microlaser or a near-infrared mode-locked Ti:sapphire laser, respectively. The microstructure resolution depends on the laser power, but is typically limited by the size of the laser beam within the sample. The cross-linking of type I collagen with Rose Bengal is obtained in acidic conditions with a large photosensitizer concentration in the millimole range. The biocompatibility of microstructures was demonstrated by observing the specific adhesion of cells on collagen lines.
Complete list of metadatas

Cited literature [8 references]  Display  Hide  Download

https://www.hal.inserm.fr/inserm-00144702
Contributor : Alain Duperray <>
Submitted on : Tuesday, May 11, 2010 - 2:04:55 PM
Last modification on : Thursday, December 12, 2019 - 9:48:05 AM
Long-term archiving on: : Thursday, September 16, 2010 - 12:10:47 PM

Identifiers

  • HAL Id : inserm-00144702, version 1

Collections

U823 | CNRS | LIPHY | UGA

Citation

Monica Iosin, Olivier Stephan, Simion Astilean, Alain Duperray, Patrice Baldeck. Microstructuration of protein matrices by laser-induced photochemistry. Journal of Optoelectronics and Advanced Materials, 2007, 9 (3), pp.716-720. ⟨inserm-00144702⟩

Share

Metrics

Record views

511

Files downloads

511