M. Berridge, M. Bootman, and P. Lipp, Calcium ? a life and death signal, Nature, vol.935, pp.645-648, 1998.

G. Brough, S. Wu, D. Cioffi, T. Moore, M. Li et al., Contribution of endogenously expressed Trp1 to a Ca2+-selective, store-operated Ca2+ entry pathway, The FASEB Journal, vol.15, issue.10, pp.1727-1738, 2001.
DOI : 10.1096/fj.01-0108com

F. Braun, L. Broad, D. Armstrong, J. Putney, and . Jr, Stable Activation of Single Ca2+ Release-activated Ca2+ Channels in Divalent Cation-free Solutions, Journal of Biological Chemistry, vol.276, issue.2, pp.1063-1070, 2001.
DOI : 10.1074/jbc.M008348200

H. Brauner-osborne and M. Brann, Pharmacology of muscarinic acetylcholine receptor subtypes (m1???m5): high throughput assays in mammalian cells, European Journal of Pharmacology, vol.295, issue.1, pp.93-102, 1996.
DOI : 10.1016/0014-2999(95)00639-7

M. Caulfield, Muscarinic Receptors???Characterization, coupling and function, Pharmacology & Therapeutics, vol.58, issue.3, pp.319-379, 1993.
DOI : 10.1016/0163-7258(93)90027-B

C. Chapple, R. Burt, P. Andersson, P. Greengrass, M. Wyllie et al., -adrenoceptor subtypes in the human prostate, British Journal of Urology, vol.149, issue.5, pp.585-589, 1994.
DOI : 10.1111/j.1464-410X.1994.tb09188.x

URL : https://hal.archives-ouvertes.fr/hal-00576628

D. Clapham, L. Runnels, and C. Strubing, The trp ion channel family, Nature Reviews Neuroscience, vol.4, issue.6, pp.387-396, 2001.
DOI : 10.1038/35077544

J. Diver, S. Sage, and J. Rosado, The inositol trisphosphate receptor antagonist 2-aminoethoxydiphenylborate (2-APB) blocks Ca2+ entry channels in human platelets: cautions for its use in studying Ca2+ influx, Cell Calcium, vol.30, issue.5, pp.323-329, 2001.
DOI : 10.1054/ceca.2001.0239

J. Exton, The roles of calcium and phosphoinositides in the mechanisms of ?? 1-adrenergic and other agonists, Rev Physiol Biochem Pharmacol, vol.111, pp.117-224, 1988.
DOI : 10.1007/BFb0033873

R. Fukasawa, N. Taniguchi, N. Moriyama, Y. Ukai, S. Yamazaki et al., The alpha1L-adrenoceptor subtype in the lower urinary tract: a comparison of human urethra and prostate, BJU International, vol.25, issue.5, pp.733-737, 1998.
DOI : 10.1097/00005392-199703000-00101

B. Hille, Ion Channels of Exitable Membranes, pp.343-344, 2001.

T. Hofmann, A. Obukhov, M. Schaefer, C. Harteneck, T. Gudermann et al., Ditect activation of human TRPC6 and TRP3 channels by diacylglycerol, Nature, vol.397, pp.259-263, 1999.

J. Horoszewicz, S. Leong, E. Kawinski, J. Karr, H. Rosenthal et al., LNCaP model of human prostatic carcinoma, Cancer Res, vol.43, pp.1809-1818, 1983.

R. Inoue, T. Okada, H. Onoue, Y. Hara, S. Shimizu et al., The Transient Receptor Potential Protein Homologue TRP6 Is the Essential Component of Vascular ??1-Adrenoceptor-Activated Ca2+-Permeable Cation Channel, Circulation Research, vol.88, issue.3, pp.325-332, 2001.
DOI : 10.1161/01.RES.88.3.325

M. Kamouchi, S. Philipp, V. Flockerzi, U. Wissenbach, A. Mamin et al., Properties of heterologously expressed hTRP3 channels in bovine pulmonary artery endothelial cells, The Journal of Physiology, vol.105, issue.2, pp.345-358, 1999.
DOI : 10.1111/j.1469-7793.1999.0345p.x

K. Kiselyov, X. Xu, G. Mozhayeva, T. Kuo, I. Pessah et al., Functional interaction between InsP3 receptors and store-operated Htrp3 channels, Nature, vol.396, pp.478-482, 1998.

B. Lintschinger, M. Balzer-geldsetzer, T. Baskaran, W. Graier, C. Romanin et al., Coassembly of Trp1 and Trp3 proteins generates diacylglycerol-and Ca 2+ -sensitive cation channels, J Biol Chem, vol.275, pp.27799-27805, 2000.

G. Luthin, P. Wang, H. Zhou, D. Dhanasekaran, and M. Ruggieri, Role of m1 receptor-G protein coupling in cell proliferation in the prostate, Life Sciences, vol.60, issue.13-14, pp.963-968, 1997.
DOI : 10.1016/S0024-3205(97)00035-0

I. Marshall, R. Burt, and C. Chapple, Signal Transduction Pathways Associated with &alpha;<sub>1</sub>-Adrenoceptor Subtypes in Cells and Tissues Including Human Prostate, European Urology, vol.36, issue.Suppl. 1, pp.42-47, 1999.
DOI : 10.1159/000052317

K. Mcvary, K. Mckenna, and C. Lee, Prostate innervation, Prostate, vol.8, pp.2-13, 1998.

B. Nilius, J. Prenen, R. Vennekens, J. Hoenderop, R. Bindels et al., channel ECaC1, British Journal of Pharmacology, vol.410, issue.3, pp.453-462, 2001.
DOI : 10.1038/sj.bjp.0704272

T. Okada, R. Inoue, K. Yamazaki, A. Maeda, T. Kurosaki et al., Molecular and Functional Characterization of a Novel Mouse Transient Receptor Potential Protein Homologue TRP7: Ca2+-PERMEABLE CATION CHANNEL THAT IS CONSTITUTIVELY ACTIVATED AND ENHANCED BY STIMULATION OF G PROTEIN-COUPLED RECEPTOR, Journal of Biological Chemistry, vol.274, issue.39, pp.27359-27370, 1999.
DOI : 10.1074/jbc.274.39.27359

J. Peng, L. Zhuang, U. Berger, R. Adam, B. Williams et al., CaT1 Expression Correlates with Tumor Grade in Prostate Cancer, Biochemical and Biophysical Research Communications, vol.282, issue.3, pp.729-734, 2001.
DOI : 10.1006/bbrc.2001.4638

J. Pennefather, W. Lau, F. Mitchelson, and S. Ventura, The autonomic and sensory innervation of the smooth muscle of the prostate gland: a review of pharmacological and histological studies, Journal of Autonomic Pharmacology, vol.232, issue.4, pp.193-206, 2000.
DOI : 10.1016/0014-2999(94)90571-1

A. Perraud, A. Fleig, C. Dunn, L. Bagley, P. Launay et al., ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology, Nature, vol.411, issue.6837, pp.595-599, 2001.
DOI : 10.1038/35079100

A. Plonowski, A. Schally, A. Nagy, K. Groot, M. Krupa et al., Inhibition of in vivo proliferation of MDA-PCa-2b human prostate cancer by a targeted cytotoxic analog of luteinizing hormone-releasing hormone AN-207, Cancer Letters, vol.176, issue.1, pp.57-63, 2002.
DOI : 10.1016/S0304-3835(01)00734-0

A. Pousette, K. Carlstrom, P. Henriksson, M. Grande, and R. Stege, Use of a hormone-sensitive (LNCaP) and a hormone-resistant (LNCaP-r) cell line in prostate cancer research, The Prostate, vol.57, issue.3, pp.198-203, 1997.
DOI : 10.1002/(SICI)1097-0045(19970515)31:3<198::AID-PROS9>3.0.CO;2-H

D. Price, D. Schwinn, J. Lomasney, L. Allen, M. Caron et al., Identification, quantification, and localization of mRNA for three distinct a 1 adrenergic receptor subtypes in human prostate, J Urol, vol.150, pp.546-551, 1993.

M. Roudbaraki, A. Lorsignol, L. Langouche, G. Callewaert, H. Vankelecom et al., Target cells of gamma3- melanocyte-stimulating hormone detected through intracellular Ca 2+ responses in immature rat pituitary constitute a fraction of all main pituitary cell types, but mostly express multiple hormone phenotypes at the messenger ribonucleic acid level. Refractoriness to melanocortin-3 receptor blockade in the lacto-somatotroph lineage, Endocrinology, vol.140, pp.4874-4885, 1999.

M. Ruggieri, M. Colton, P. Wang, J. Wang, R. Smyth et al., Human prostate muscarinic receptor subtypes, J Pharmacol Exp Ther, vol.274, pp.976-982, 1995.

R. Skryma, N. Prevarskaya, L. Dufy-barbe, M. Odessa, J. Audin et al., Potassium conductance in the androgen-sensitive prostate cancer cell line, LNCaP: Involvement in cell proliferation, The Prostate, vol.322, issue.2, pp.112-122, 1997.
DOI : 10.1002/(SICI)1097-0045(19971001)33:2<112::AID-PROS5>3.0.CO;2-M

M. Takeda, A. Hatano, K. Arai, K. Obara, T. Tsutsui et al., &alpha;<sub>1</sub>- and &alpha;<sub>2</sub>-Adrenoceptors in BPH, BPH, pp.31-34, 1999.
DOI : 10.1159/000052315

J. Tang, Y. Lin, Z. Zhang, S. Tikunova, L. Birnbaumer et al., Identification of Common Binding Sites for Calmodulin and Inositol 1,4,5-Trisphosphate Receptors on the Carboxyl Termini of Trp Channels, Journal of Biological Chemistry, vol.276, issue.24, pp.21303-21310, 2001.
DOI : 10.1074/jbc.M102316200

Y. Tesfai, H. Brereton, and G. Barritt, A diacylglycerol-activated Ca2+ channel in PC12 cells (an adrenal chromaffin cell line) correlates with expression of the TRP-6 (transient receptor potential) protein, Biochemical Journal, vol.358, issue.3, pp.717-726, 2001.
DOI : 10.1042/bj3580717

L. Tsavaler, M. Shapero, S. Morkowski, and R. Laus, Trp-p8, a novel prostate-specific gene, is up-regulated in prostate cancer and other malignancies and shares high homology with transient receptor potential calcium channel proteins, Cancer Res, vol.61, pp.3760-3769, 2001.

G. Vazquez, J. Lievremont, J. St, G. Bird, J. Putney et al., Human Trp3 forms both inositol trisphosphate receptordependent and receptor-independent store-operated cation channels in DT40 avian B lymphocytes, Proc Natl Acad Sci, pp.11777-11782, 2001.

S. Ventura, J. Pennefather, and F. Mitchelson, Cholinergic innervation and function in the prostate gland, Pharmacology & Therapeutics, vol.94, issue.1-2, pp.93-112, 2002.
DOI : 10.1016/S0163-7258(02)00174-2

T. Voets, J. Prenen, A. Fleig, R. Vennekens, H. Watanabe et al., CaT1 and the calcium release-activated calcium channel manifest distinct pore properties, J Biol Chem, vol.276, pp.47767-47770, 2001.

P. Walden, C. Gerardi, and H. Lepor, Localization and expression of the a 1A-1, a 1B and a 1D-adrenoreceptors in hyperplastic and non-hyperplastic human prostate, J Urol, vol.61, pp.635-640, 1999.

H. Watanabe, J. Davis, D. Smart, J. Jerman, G. Smith et al., Activation of TRPV4 Channels (hVRL-2/mTRP12) by Phorbol Derivatives, Journal of Biological Chemistry, vol.277, issue.16, pp.13569-13577, 2002.
DOI : 10.1074/jbc.M200062200

U. Wissenbach, B. Niemeyer, T. Fixemer, A. Schneidewind, C. Trost et al., Expression of CaT-like, a Novel Calcium-selective Channel, Correlates with the Malignancy of Prostate Cancer, Journal of Biological Chemistry, vol.276, issue.22, 2001.
DOI : 10.1074/jbc.M009895200

D. Wu, A. Katz, C. Lee, and M. Simon, activation of phospholipase C by a 1-adrenergic receptors is mediated by the a subunit of Gq family, J Biol Chem, vol.67, pp.25798-25802, 1992.

X. Wu, G. Babnigg, and M. Villereal, Functional significance of human trp1 and trp3 in store-operated Ca 2+ entry in HEK-293 cells, Am J Physiol Cell Physiol, vol.278, pp.526-536, 2000.

L. Zhang and D. Saffen, Muscarinic Acetylcholine Receptor Regulation of TRP6 Ca2+ Channel Isoforms. MOLECULAR STRUCTURES AND FUNCTIONAL CHARACTERIZATION, Journal of Biological Chemistry, vol.276, issue.16, pp.13331-13339, 2001.
DOI : 10.1074/jbc.M008914200

H. Zhong and K. Minneman, ??1-Adrenoceptor subtypes, European Journal of Pharmacology, vol.375, issue.1-3, pp.261-276, 1999.
DOI : 10.1016/S0014-2999(99)00222-8

X. Zhu, M. Jiang, and L. Birnbaumer, Receptor-activated Ca2+ Influx via Human Trp3 Stably Expressed in Human Embryonic Kidney (HEK)293 Cells: EVIDENCE FOR A NON-CAPACITATIVE Ca2+ ENTRY, Journal of Biological Chemistry, vol.273, issue.1, pp.133-142, 1998.
DOI : 10.1074/jbc.273.1.133

C. Zitt, C. Halaszovich, and A. Luckhoff, The TRP family of cation channels: probing and advancing the concepts on receptor-activated calcium entry, Progress in Neurobiology, vol.66, issue.4, pp.243-264, 2002.
DOI : 10.1016/S0301-0082(02)00002-3

C. Zitt, A. Obukhov, C. Strubing, A. Zobel, F. Kalkbrenner et al., Expression of TRPC3 in Chinese Hamster Ovary Cells Results in Calcium-activated Cation Currents Not Related to Store Depletion, The Journal of Cell Biology, vol.267, issue.6, pp.1333-1341, 1997.
DOI : 10.1073/pnas.90.13.6295