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Local backbone structure prediction of proteins.

Abstract : A statistical analysis of the PDB structures has led us to define a new set of small 3D structural prototypes called Protein Blocks (PBs). This structural alphabet includes 16 PBs, each one is defined by the (phi, psi) dihedral angles of 5 consecutive residues. The amino acid distributions observed in sequence windows encompassing these PBs are used to predict by a Bayesian approach the local 3D structure of proteins from the sole knowledge of their sequences. LocPred is a software which allows the users to submit a protein sequence and performs a prediction in terms of PBs. The prediction results are given both textually and graphically.
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Contributor : Alexandre G. de Brevern <>
Submitted on : Monday, February 26, 2007 - 1:55:41 PM
Last modification on : Tuesday, December 8, 2020 - 3:40:42 AM
Long-term archiving on: : Tuesday, April 6, 2010 - 10:50:06 PM


  • HAL Id : inserm-00132872, version 1
  • PUBMED : 15724288


Alexandre de Brevern, Cristina Benros, Romain Gautier, Hélène Valadié, Serge Hazout, et al.. Local backbone structure prediction of proteins.. In Silico Biol, 2004, 4 (3), pp.381-6. ⟨inserm-00132872⟩



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