R. Snidjers, P. Noble, N. Sebire, A. Souka, and K. Nicolaides, UK multicentre project on assessment of risk of trisomy 21 by maternal age and fetal nuchal translucency thickness at 10-14 weeks of gestation, Lancet, vol.351, pp.343-349, 1998.

J. Hyett, M. Perdu, G. Sharland, R. Snidjers, and K. Nicolaides, Using fetal nuchal translucency to screen for major congenital cardiac defects at 10-14??weeks of gestation: population based cohort study, BMJ, vol.318, issue.7176, pp.81-85, 1999.
DOI : 10.1136/bmj.318.7176.81

A. Souka, R. Snidjers, A. Novakov, W. Soares, and K. Nicolaides, Defects and syndromes in chromosomally normal fetuses with increased nuchal translucency thickness at 10-14 weeks of gestation, Ultrasound in Obstetrics and Gynecology, vol.11, issue.6, pp.391-400, 1998.
DOI : 10.1046/j.1469-0705.1998.11060391.x

G. Michailidis and D. Economides, Nuchal translucency measurement and pregnancy outcome in karyotypically normal fetuses, Ultrasound in Obstetrics and Gynecology, vol.106, issue.2, pp.102-105, 2001.
DOI : 10.1159/000020817

E. Malvrides, F. Cobian-sanchez, A. Tekay, G. Moscoso, S. Campbell et al., Limitations of using first-trimester nuchal translucency measurement in routine screening for major congenital heart defects, Ultrasound in Obstetrics and Gynecology, vol.96, issue.2, pp.106-110, 2001.
DOI : 10.1046/j.1469-0705.1993.03050310.x

A. Souka, V. Kaisenberg, C. Hyett, J. Sonek, J. Nicolaides et al., Increased nuchal translucency with normal karyotype, American Journal of Obstetrics and Gynecology, vol.192, issue.4, pp.1005-1021, 2005.
DOI : 10.1016/j.ajog.2004.12.093

V. Vugt, J. Tinnemans, and B. Van-zalen-sprock, Outcome and early childhood follow-up of chromosomally normal fetuses with increased nuchal translucency at 10-14 weeks' gestation, Ultrasound in Obstetrics and Gynecology, vol.11, issue.6, pp.407-409, 1998.
DOI : 10.1046/j.1469-0705.1998.11060407.x

O. Adekunle, A. Goppe, M. El-sayed, and B. Thilaganathan, Increased first trimester nuchal translucency: pregnancy and infant outcomes after routine screening for Down's syndrome in an unselected antenatal population., The British Journal of Radiology, vol.72, issue.857, pp.457-460, 1999.
DOI : 10.1259/bjr.72.857.10505009

R. Maymon, E. Jauniaux, O. Cohen, E. Dreazen, Z. Weinraub et al., Pregnancy outcome and infant follow-up of fetuses with abnormally increased first trimester nuchal translucency, Human Reproduction, vol.15, issue.9
DOI : 10.1093/humrep/15.9.2023

A. Brady, P. Pandya, B. Yuksel, A. Greenough, M. Patton et al., Outcome of chromosomally normal livebirths with increased fetal nuchal translucency at 10-14 weeks' gestation., Journal of Medical Genetics, vol.35, issue.3, pp.222-246, 1998.
DOI : 10.1136/jmg.35.3.222

A. Hiippala, M. Eronen, P. Taipale, R. Salonen, and V. Hiilesmaa, Fetal nuchal translucency and normal chromosomes: a long-term follow-up study, Ultrasound in Obstetrics and Gynecology, vol.76, issue.1, pp.18-22, 2001.
DOI : 10.1046/j.1469-0705.2001.00341.x

M. Senat, D. Keersmaecker, B. Audibert, F. Montcharmont, G. Frydman et al., Pregnancy outcome in fetuses with increased nuchal translucency and normal karyotype, Prenatal Diagnosis, vol.11, issue.5, pp.345-354, 2002.
DOI : 10.1002/pd.321

C. Cheng, R. Bahado-singh, S. Chen, and M. Tsai, Pregnancy outcomes with increased nuchal translucency after routine Down syndrome screening, International Journal of Gynecology & Obstetrics, vol.14, issue.1, pp.5-9, 2004.
DOI : 10.1016/S0020-7292(03)00206-6

A. Souka, E. Krampl, S. Bakalis, V. Heath, and K. Nicolaides, Outcome of pregnancy in