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Single-scan quantitative T2* methods with susceptibility artifact reduction.

Abstract : Two imaging methods, MSSAVE (Multiple echo SubSlice AVEraging imaging), based on sub-slice averaging and MGESEPI (Multiple echo Gradient-Echo Slice-Excitation Profile Imaging), based on over-sampling in the slice direction, are proposed for single-scan quantitative T(2)* evaluation with susceptibility artifact compensation. Their potentials in terms of sensitivity, minimum performance time, susceptibility artifact reduction and T(2)* quantitation quality, were compared with existing single-scan methods such as classical FLASH two- or three-dimensional or z-shimmed methods both in vitro and in vivo in normal rat brain. MGESEPI offered good quality T(2)* maps nearly free of artifacts but required a long acquisition time. MSSAVE was faster, but at the expense of reduced artifact compensation and the achievable T(2)* quantitation quality.
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Contributor : Laurent Lemaire <>
Submitted on : Monday, February 5, 2007 - 5:33:09 PM
Last modification on : Wednesday, May 20, 2020 - 4:38:02 PM

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Florence Franconi, Pierre Mowat, Laurent Lemaire, Pascal Richomme, Jean-Jacques Le Jeune. Single-scan quantitative T2* methods with susceptibility artifact reduction.. NMR in Biomedicine, Wiley, 2006, 19 (5), pp.527-34. ⟨10.1002/nbm.1014⟩. ⟨inserm-00129099⟩



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