M. Alexander, M. Miller, D. Dorsa, B. Bullock, R. Melloni et al., Distribution of neurotensin/neuromedin N mRNA in rat forebrain: unexpected abundance in hippocampus and subiculum., Proceedings of the National Academy of Sciences, vol.86, issue.13, pp.5202-5206, 1989.
DOI : 10.1073/pnas.86.13.5202

M. Azzi, H. Boudin, N. Mahmudi, D. Pélaprat, W. Rostène et al., In vivo regulation of neurotensin receptors following long-term pharmacological blockade with a specific receptor antagonist, Molecular Brain Research, vol.42, issue.2, pp.213-221, 1996.
DOI : 10.1016/S0169-328X(96)00124-6

M. Azzi, A. Nicot, D. Gully, P. Kitabgi, A. Bérod et al., Increase in neurotensin receptor expression in rat brain induced by chronic treatment with the nonpeptide neurotensin receptor antagonist SR 48692, Neuroscience Letters, vol.172, issue.1-2, pp.97-100, 1994.
DOI : 10.1016/0304-3940(94)90671-8

G. Bennett, S. Moss, C. Forster, and C. Marsden, Developmental changes in neurotensin and its metabolites in the neonatal rat, Developmental Brain Research, vol.111, issue.2, pp.189-196, 1998.
DOI : 10.1016/S0165-3806(98)00137-0

C. Betancur, M. Canton, A. Burgos, B. Labeeuw, D. Gully et al., Characterization of binding sites of a new neurotensin receptor antagonist, []SR 142948A, in the rat brain, European Journal of Pharmacology, vol.343, issue.1, pp.67-77, 1998.
DOI : 10.1016/S0014-2999(97)01510-0

URL : https://hal.archives-ouvertes.fr/inserm-00276332

G. Bissette, C. Richardson, J. Kizer, and C. Nemeroff, Ontogeny of Brain Neurotensin in the Rat: A Radioimmunoassay Study, Journal of Neurochemistry, vol.206, issue.1, pp.283-287, 1984.
DOI : 10.1007/BF00965728

I. Camby, I. Salmon, E. Bourdel, N. Nagy, A. Danguy et al., Neurotensin-mediated effects on astrocytic tumor cell proliferation, Neuropeptides, vol.30, issue.2, pp.133-139, 1996.
DOI : 10.1016/S0143-4179(96)90080-3

P. Chalon, N. Vita, M. Kaghad, M. Guillemot, J. Bonnin et al., Molecular cloning of a levocabastine-sensitive neurotensin binding site, FEBS Letters, vol.333, issue.2-3, pp.91-94, 1996.
DOI : 10.1016/0014-5793(96)00397-3

Y. Cheng and W. Prusoff, Relationship between the inhibition constant (K i ) and the concentration of inhibitor which causes 50 percent inhibition (IC 5 0 ) of an enzymatic reaction, Biochem Pharmacol, vol.22, pp.3099-3108, 1973.

P. Chomczynski and N. Sacchi, Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction, Analytical Biochemistry, vol.162, issue.1, pp.156-159, 1987.
DOI : 10.1016/0003-2697(87)90021-2

S. Doulut, M. Rodriguez, D. Lugrin, F. Vecchini, P. Kitabgi et al., Reduced peptide bond pseudopeptide analogues of neurotensin, Peptide Res, vol.5, pp.30-38, 1992.

I. Dubuc, P. Sarret, C. Labbé-jullié, J. Botto, E. Honoré et al., Identification of the receptor subtype involved in the analgesic effect of neurotensin, J Neurosci, vol.19, pp.1-8, 1999.

R. Ehlers, R. Bonnor, X. Wang, M. Hellmich, and B. Evers, Signal transduction mechanisms in neurotensin-mediated cellular regulation, Surgery, vol.124, issue.2, pp.239-246, 1998.
DOI : 10.1016/S0039-6060(98)70126-6

B. Evers, M. Izukura, D. Chung, D. Parekh, K. Yoshinaga et al., Neurotensin stimulates growth of colonic mucosa in young and aged rats, Gastroenterology, vol.103, issue.1, pp.86-91, 1992.
DOI : 10.1016/0016-5085(92)91099-P

I. Ferrer, E. Soriano, J. Del-rio, S. Alcantara, and C. Auladell, Cell death and removal in the cerebral cortex during development, Progress in Neurobiology, vol.39, issue.1, pp.1-43, 1992.
DOI : 10.1016/0301-0082(92)90029-E

D. Gully, M. Canton, R. Boigegrain, F. Jeanjean, J. Molimard et al., Biochemical and pharmacological profile of a potent and selective nonpeptide antagonist of the neurotensin receptor., Proceedings of the National Academy of Sciences, vol.90, issue.1, pp.65-69, 1993.
DOI : 10.1073/pnas.90.1.65

Y. Hara, S. Shiosaka, E. Senba, M. Sakanaka, S. Inagaki et al., Ontogeny of the neurotensin-containing neuron system of the rat: Immunohistochemical analysis. I. Forebrain and diencephalon, The Journal of Comparative Neurology, vol.35, issue.2, pp.177-195, 1982.
DOI : 10.1002/cne.902080207

K. Hasegawa, S. Kar, and B. Carr, Stimulation of hepatocyte DNA synthesis by neurotensin, Journal of Cellular Physiology, vol.45, issue.2, pp.215-222, 1994.
DOI : 10.1002/jcp.1041580202

E. Hermans and J. Maloteaux, Mechanisms of Regulation of Neurotensin Receptors, Pharmacology & Therapeutics, vol.79, issue.2, pp.89-104, 1998.
DOI : 10.1016/S0163-7258(98)00009-6

J. Hill, R. Mervis, J. Politi, S. Mccune, I. Gozes et al., Blockade of VIP during Neonatal Development Induces Neuronal Damage and Increases VIP and VIP Receptors in Brain, Annals of the New York Academy of Sciences, vol.18, issue.1 Models of Neu, pp.211-225, 1994.
DOI : 10.1038/335639a0

H. Kiyama, M. Sato, and P. Emson, Ontogeny of neurotensin immunoreactivity and mRNA in the rat central nervous system Ontogeny of neurotransmitters and peptides in the CNS, Handbook of chemical neuroanatomy, pp.399-431, 1992.

E. Kudlacz, J. Spencer, and T. Slotkin, Postnatal alterations in ß-adrenergic receptor binding in rat brain regions after continuous prenatal exposure to propranolol via maternal infusion, Res Commun Chem Pathol Pharmacol, vol.71, pp.153-161, 1991.

P. Lambert, R. Gross, C. Nemeroff, and C. Kilts, Anatomy and Mechanisms of Neurotensin-Dopamine Interactions in the Central Nervous System, Annals of the New York Academy of Sciences, vol.112, issue.4, pp.377-389, 1995.
DOI : 10.1111/j.1749-6632.1995.tb17496.x

J. Lauder, Neurotransmitters as growth regulatory signals: role of receptors and second messengers, Trends in Neurosciences, vol.16, issue.6, pp.233-240, 1993.
DOI : 10.1016/0166-2236(93)90162-F

I. Lépée-lorgeoux, C. Betancur, W. Rostène, and D. Pélaprat, Differential ontogenetic patterns of levocabastine-sensitive neurotensin NT2 receptors and of NT1 receptors in the rat brain revealed by in situ hybridization, Developmental Brain Research, vol.113, issue.1-2, pp.115-131, 1999.
DOI : 10.1016/S0165-3806(99)00009-7

J. Liu, K. Brannen, D. Grayson, A. Morrow, L. Devaud et al., Prenatal Exposure to the Pesticide Dieldrin or the GABA<sub>A</sub> Receptor Antagonist Bicuculline Differentially Alters Expression of GABA<sub>A</sub> Receptor Subunit mRNAs in Fetal Rat Brainstem, Developmental Neuroscience, vol.20, issue.1, pp.83-92, 1998.
DOI : 10.1159/000017302

J. Mazella, J. Botto, E. Guillemare, T. Coppola, P. Sarret et al., Structure, functional expression, and cerebral localization of the levocabastine-sensitive neurotensin/neuromedin N receptor from mouse brain, J Neurosci, vol.16, pp.5613-5620, 1996.

J. Mazella, N. Zsürger, V. Navarro, J. Chabry, M. Kaghad et al., The 100-kDa Neurotensin Receptor Is gp95/Sortilin, A Non-G-Protein-coupled Receptor, Journal of Biological Chemistry, vol.273, issue.41, pp.26273-26276, 1998.
DOI : 10.1074/jbc.273.41.26273

P. Munson and D. Rodbard, LIGAND: A versatile computerized approach for characterization of ligand-binding systems, Analytical Biochemistry, vol.107, issue.1, pp.220-239, 1980.
DOI : 10.1016/0003-2697(80)90515-1

M. Najimi, F. Souazé, M. Méndez, E. Hermans, T. Berbar et al., Activation of Receptor Gene Transcription Is Required to Maintain Cell Sensitization after Agonist Exposure: STUDY ON NEUROTENSIN RECEPTOR, Journal of Biological Chemistry, vol.273, issue.34, pp.21634-21641, 1998.
DOI : 10.1074/jbc.273.34.21634

C. Nemeroff and P. Kitabgi, The neurobiology of neurotensin, Ann N Y Acad Sci, vol.668, pp.1-374, 1992.

K. Nishimori, L. Young, Q. Guo, Z. Wang, T. Insel et al., Oxytocin is required for nursing but is not essential for parturition or reproductive behavior., Proceedings of the National Academy of Sciences, vol.93, issue.21, pp.11699-11704, 1996.
DOI : 10.1073/pnas.93.21.11699

O. Leary, D. Koester, and S. , Development of projection neuron types, axon pathways, and patterned connections of the mammalian cortex, Neuron, vol.10, issue.6, pp.991-1006, 1993.
DOI : 10.1016/0896-6273(93)90049-W

J. Palacios, A. Pazos, M. Dietl, M. Schlumpf, and W. Lichtensteiger, The ontogeny of brain neurotensin receptors studied by autoradiography, Neuroscience, vol.25, issue.1, pp.307-317, 1988.
DOI : 10.1016/0306-4522(88)90028-0

J. Parnavelas and M. Cavanagh, Transient expression of neurotransmitters in the developing neocortex, Trends in Neurosciences, vol.11, issue.3, pp.92-93, 1988.
DOI : 10.1016/0166-2236(88)90150-6

D. Pélaprat, I. Dusart, and M. Peschanski, Postnatal development of cholecystokinin (CCK) binding sites in the rat forebrain and midbrain: an autoradiographic study, Developmental Brain Research, vol.44, issue.1, pp.119-132, 1988.
DOI : 10.1016/0165-3806(88)90123-X

W. Rostène and M. Alexander, Neurotensin and Neuroendocrine Regulation, Frontiers in Neuroendocrinology, vol.18, issue.2, pp.115-173, 1997.
DOI : 10.1006/frne.1996.0146

M. Sato, H. Kiyama, and M. Tohyama, Different postnatal development of cells expressing mRNA encoding neurotensin receptor, Neuroscience, vol.48, issue.1, pp.137-149, 1992.
DOI : 10.1016/0306-4522(92)90344-2

M. Sato, H. Kiyama, S. Yoshida, T. Saika, and M. Tohyama, Postnatal ontogeny of cells expressing prepro-neurotensin/neuromedin N mRNA in the rat forebrain and midbrain: A hybridization histochemical study involving isotope-labeled and enzyme-labeled probes, The Journal of Comparative Neurology, vol.303, issue.3, pp.300-315, 1991.
DOI : 10.1002/cne.903100303

V. Scarcériaux, D. Pélaprat, A. Lhiaubet, R. Schimpf, G. Tramu et al., Developmental pattern of neurotensin content in rat hypothalamic neurons cultured in serum-free medium: comparison with in vivo data, Developmental Brain Research, vol.81, issue.1, pp.128-130, 1995.
DOI : 10.1016/0165-3806(94)90075-2

V. Scarcériaux, F. Souazé, C. Bachelet, P. Forgez, E. Bourdel et al., Neurotensin Receptor Down-Regulation Induced by Dexamethasone and Forskolin in Rat Hypothalamic Cultures is Mediated by Endogenous Neurotensin, Journal of Neuroendocrinology, vol.8, issue.8, pp.587-593, 1996.
DOI : 10.1046/j.1365-2826.1996.04933.x

A. Schotte and P. Laduron, Different postnatal ontogeny of two [3H]neurotensin binding sites in rat brain, Brain Research, vol.408, issue.1-2, pp.326-328, 1987.
DOI : 10.1016/0006-8993(87)90398-2

A. Schotte, J. Leysen, and P. Laduron, Evidence for a displaceable non-specific [3H]neurotensin binding site in rat brain, Naunyn-Schmiedeberg's Archives of Pharmacology, vol.10, issue.4, pp.400-405, 1986.
DOI : 10.1007/BF00500016

I. Sehgal, S. Powers, B. Huntley, G. Powis, M. Pittelkow et al., Neurotensin is an autocrine trophic factor stimulated by androgen withdrawal in human prostate cancer., Proceedings of the National Academy of Sciences, vol.91, issue.11, pp.4673-4677, 1994.
DOI : 10.1073/pnas.91.11.4673

R. Sircar, P. Follesa, and M. Ticku, Postnatal phencyclidine treatment differentially regulates N-methyl-d-aspartate receptor subunit mRNA expression in developing rat cerebral cortex, Molecular Brain Research, vol.40, issue.2, pp.214-220, 1996.
DOI : 10.1016/0169-328X(96)00051-4

F. Souazé, W. Rostène, and P. Forgez, Neurotensin agonist induces differential regulation of neurotensin receptor mRNA, J Biol Chem, vol.272, pp.10087-10094, 1997.

Z. Speiser, I. Gordon, M. Rehavi, and S. Gitter, Behavioral and biochemical studies in rats following prenatal treatment with ??-adrenoceptor antagonists, European Journal of Pharmacology, vol.195, issue.1, pp.75-83, 1991.
DOI : 10.1016/0014-2999(91)90383-2

K. Tanaka, M. Masu, and S. Nakanishi, Structure and functional expression of the cloned rat neurotensin receptor, Neuron, vol.4, issue.6, pp.847-854, 1990.
DOI : 10.1016/0896-6273(90)90137-5

M. Taoka, S. Song, M. Kubota, A. Minegishi, T. Yamakuni et al., Increased level of neurokinin-1 tachykinin receptor gene expression during early postnatal development of rat brain, Neuroscience, vol.74, issue.3, pp.845-853, 1996.
DOI : 10.1016/0306-4522(96)00198-4

E. Tribollet, M. Goumaz, M. Raggenbass, M. Dubois-dauphin, and J. Dreifuss, Early appearance and transient expression of vasopressin receptors in the brain of rat fetus and infant. An autoradiographical and electrophysiological study, Developmental Brain Research, vol.58, issue.1, pp.13-24, 1991.
DOI : 10.1016/0165-3806(91)90232-8

N. Vita, P. Laurent, S. Lefort, P. Chalon, X. Dumont et al., Cloning and expression of a complementary DNA encoding a high affinity human neurotensin receptor, FEBS Letters, vol.140, issue.1-2, pp.139-142, 1993.
DOI : 10.1016/0014-5793(93)81509-X

L. Zhang and R. Harlan, Ontogeny of the distribution of tachykinins in rat cerebral cortex: immunocytochemistry and in situ hybridization histochemistry, Developmental Brain Research, vol.77, issue.1, pp.23-36, 1994.
DOI : 10.1016/0165-3806(94)90210-0

Q. Zhou and R. Palmiter, Dopamine-deficient mice are severely hypoactive, adipsic, and aphagic, Cell, vol.83, issue.7, pp.1197-1209, 1995.
DOI : 10.1016/0092-8674(95)90145-0