C. Todd, D. Colley, R. Ramzy, M. Habib, A. El et al., Comparison of whole blood cultures and peripheral blood mononuclear cell cultures for evaluation of lymphocyte reactivity during chronic schistosomiasis, Transactions of the Royal Society of Tropical Medicine and Hygiene, vol.75, issue.6, pp.783-790, 1981.
DOI : 10.1016/0035-9203(81)90412-0

D. Colley, A. Garcia, J. Lambertucci, J. Parra, N. Katz et al., Immune responses during human schistosomiasis . XII. Differential responsiveness in patients with hepatosplenic disease, Am J Trop Med Hyg, vol.35, pp.793-802, 1986.

A. Butterworth, D. Dunne, A. Fulford, J. Ouma, and R. Sturrock, Immunity and morbidity in Schistosoma mansoni infection: quantitative aspects, Am. J. Trop. Med. Hyg, vol.55, pp.109-124, 1996.

P. Hagan, U. Blumenthal, D. Dunn, A. Simpson, and H. Wilkins, Human IgE, IgG4 and resistance to reinfection with Schistosomahaematobium, Nature, vol.349, issue.6306, pp.243-248, 1991.
DOI : 10.1038/349243a0

D. Dunne, M. Webster, P. Smith, J. Langley, B. Richardson et al., The isolation of a 22 kDa band after SDS-PAGE of Schistosoma mansoni adult worms and its use to demonstrate that IgE responses against the antigen(s) it contains are associated with human resistance to reinfection, Parasite Immunology, vol.19, issue.2, pp.79-89, 1997.
DOI : 10.1046/j.1365-3024.1997.d01-186.x

M. Webster, P. Fallon, A. Fulford, A. Butterworth, J. Ouma et al., IgG4 and IgE Responses to Schistosoma mansoni Adult Worms after Treatment, Journal of Infectious Diseases, vol.175, issue.2, pp.493-497, 1997.
DOI : 10.1093/infdis/175.2.493

M. Webster, M. Roberts, A. Fulford, M. M. Gallisot, M. Diagne et al., Human IgE responses to rSm22.6 are associated with infection intensity rather than age per se, in a recently established focus of Schistomiasis mansoni, Tropical Medicine and International Health, vol.57, issue.4, pp.318-344, 1998.
DOI : 10.1017/S003118209600858X

L. Bahia-oliveira, G. Gazzinelli, S. Eloi-santos, J. Cunha-melo, L. Alves-oliveira et al., Differential cellular reactivity to adult worm antigens of patients with different clinical forms of schistosomiasis mansoni, Transactions of the Royal Society of Tropical Medicine and Hygiene, vol.86, issue.1, pp.57-61, 1992.
DOI : 10.1016/0035-9203(92)90441-E

E. Sabin, M. Araujo, E. Carvalho, and E. Pearce, Impairment of Tetanus Toxoid-Specific Thl-like Immune Responses in Humans Infected with Schistosoma mansoni, Journal of Infectious Diseases, vol.173, issue.1, pp.269-72, 1996.
DOI : 10.1093/infdis/173.1.269

P. Falcao, L. Malaquias, O. Martins-filho, A. Silveira, V. Passos et al., granuloma formation, Parasite Immunology, vol.151, issue.(Suppl. IV), pp.447-54, 1998.
DOI : 10.1046/j.1365-3024.1998.00166.x

O. Martins-filho, W. Dutra, G. Freeman, A. Silveira, A. Rabello et al., Flow Cytometric Study of Blood Leucocytes in Clinical Forms of Human Schistosomiasis, Scandinavian Journal of Immunology, vol.46, issue.3, pp.304-315, 1997.
DOI : 10.1046/j.1365-3083.1997.d01-119.x

K. Gollob and R. Coffman, A minority subpopulation of CD4+ T cells directs the development of naive CD4+ T cells into IL- 4-secreting cells, J Immunol, vol.152, pp.5180-5188, 1994.

W. Dutra, O. Martins-filho, J. Cancado, J. Pinto-dias, Z. Brener et al., Activated T and B lymphocytes in peripheral blood of patients with Chagas' disease, International Immunology, vol.6, issue.4, pp.499-506, 1994.
DOI : 10.1093/intimm/6.4.499

W. Dutra, K. Gollob, J. Pinto-dias, G. Gazzinelli, R. Correa-oliveira et al., Cytokine mRNA Profile of Peripheral Blood Mononuclear Cells Isolated from Individuals with Trypanosoma cruzi Chronic Infection, Scandinavian Journal of Immunology, vol.45, issue.1, pp.74-80, 1997.
DOI : 10.1046/j.1365-3083.1997.d01-362.x

C. Naus, G. Kimani, J. Ouma, A. Fulford, M. Webster et al., Development of antibody isotype responses to Schistosoma mansoni in an immunologically naive immigrant population: influence of infection duration, infection intensity, and host age, Infect Immun, vol.67, pp.3444-51, 1999.

Z. Zhang, H. Wu, S. Chen, L. Hu, Z. Xie et al., Association between IgE antibody against soluble egg antigen and resistance to reinfection with Schistosoma japonicum, Transactions of the Royal Society of Tropical Medicine and Hygiene, vol.91, issue.5, pp.606-614, 1997.
DOI : 10.1016/S0035-9203(97)90047-X

J. Grogan, P. Kremsner, G. Van-dam, W. Metzger, B. Mordmuller et al., Antischistosome IgG4 and IgE Responses Are Affected Differentially by Chemotherapy in Children versus Adults, Journal of Infectious Diseases, vol.173, issue.5, pp.1242-1249, 1996.
DOI : 10.1093/infdis/173.5.1242

A. Schuerwegh, D. Clerck, L. , D. Schutter, L. Bridts et al., Flow cytometric detection of type 1 (IL-2, I?N? amma) and type 2 (IL-4, IL-5) cytokines in T-helper and Tsuppressor/cytotoxic cells in rheumatoid arthritis, allergic asthma and atopic dermatitis, Cytokine, issue.10, pp.11783-11791, 1999.

J. Jason, Single-cell cytokine profiles in normal humans: Comparison of flow cytometric reagents and stimulation protocols, Journal of Immunological Methods, vol.207, issue.1, pp.13-22, 1997.
DOI : 10.1016/S0022-1759(97)00079-3

K. Gollob, W. Dutra, and R. Coffman, Early message expression of interleukin-4 and interferon-??, but not of interleukin-2 and interleukin-10, reflects later polarization of primary CD4+ T cell cultures, European Journal of Immunology, vol.75, issue.7, pp.1565-70, 1996.
DOI : 10.1002/eji.1830260724

S. Mahanty, J. Abrams, C. King, A. Limaye, and T. Nutman, Parallel regulation of IL-4 and IL-5 in human helminth infections, J Immunol, vol.148, pp.3567-3571, 1992.

M. Webster, R. Correa-oliveira, G. Gazzinelli, I. Viana, L. Fraga et al., Factors affecting high and low human IgE responses to schistosome worm antigens in an area of Brazil endemic for Schistosoma mansoni and hookworm, Am J Trop Med Hyg, vol.57, pp.487-94, 1997.

T. Sornasse, P. Larenas, K. Davis, J. De-vries, and H. Yssel, Differentiation and stability of T helper 1 and 2 cells derived from naive human neonatal CD4+ T cells, analyzed at the single-cell level, Journal of Experimental Medicine, vol.184, issue.2, pp.473-83, 1996.
DOI : 10.1084/jem.184.2.473

H. Yssel and H. Spits, Generation and Maintenance of Cloned Human T Cell Lines, Current Protocols in Immunology, 2002.
DOI : 10.1002/0471142735.im0719s47