. Campbell, Chromosomal insertion sites for phages and plasmids., Journal of Bacteriology, vol.174, issue.23, pp.7495-7499, 1992.
DOI : 10.1128/jb.174.23.7495-7499.1992

C. Dye, Global epidemiology of tuberculosis. The Lancet, pp.938-940, 2006.

G. Hatfull and G. Sarkis, DNA sequence, structure and gene expression of mycobacteriophage L5: a phage system for mycobacterial genetics, Molecular Microbiology, vol.82, issue.3, pp.395-405, 1993.
DOI : 10.1038/351456a0

E. Anes, I. Portugal, and J. Moniz-pereira, Insertion into the Mycobacterium smegmatis genome of the aph gene through lysogenization with the temperate mycobacteriophage Ms6, FEMS Microbiol Lett, vol.74, pp.21-25, 1992.

M. Lee, L. Pascopella, W. Jacobs, . Jr, and G. Hatfull, Site-specific integration of mycobacteriophage L5: integration-proficient vectors for Mycobacterium smegmatis, Mycobacterium tuberculosis, and bacille Calmette-Guerin., Proceedings of the National Academy of Sciences, vol.88, issue.8, pp.883111-3115, 1991.
DOI : 10.1073/pnas.88.8.3111

C. Pena, J. Stoner, and G. Hatfull, Positions of strand exchange in mycobacteriophage L5 integration and characterization of the attB site., Journal of Bacteriology, vol.178, issue.18, pp.5533-5536, 1996.
DOI : 10.1128/jb.178.18.5533-5536.1996

A. Freitas-vieira, E. Anes, and J. Moniz-pereira, The site-specific recombination locus of mycobacteriophage Ms6 determines DNA integration at the tRNA(Ala) gene of Mycobacterium spp, pp.3397-3406, 1998.

L. Bibb and G. Hatfull, Integration and excision of the Mycobacterium tuberculosis prophage-like element, ??Rv1, Molecular Microbiology, vol.184, issue.6, pp.1515-1526, 2002.
DOI : 10.1046/j.1365-2958.2002.03130.x

J. Lewis and G. Hatfull, Control of directionality in integrasemediated recombination: examination of recombination directionality factors (RDFs) including Xis and Cox proteins, Nucl Acids Res, issue.11, pp.292205-2216, 2001.

I. Méderlé, I. Bourguin, D. Ensergueix, E. Badell, J. Moniz-pereira et al., Plasmidic versus Insertional Cloning of Heterologous Genes in Mycobacterium bovis BCG: Impact on In Vivo Antigen Persistence and Immune Responses, Infection and Immunity, vol.70, issue.1, pp.303-314, 2002.
DOI : 10.1128/IAI.70.1.303-314.2002

B. Springer, P. Sander, L. Sedlacek, K. Ellrott, and E. Böttger, Instability and site-specific excision of integration-proficient mycobacteriophage L5 plasmids: development of stably maintained integrative vectors, International Journal of Medical Microbiology, vol.290, issue.8, pp.669-675, 2001.
DOI : 10.1016/S1438-4221(01)80004-7

S. Cole, R. Brosch, J. Parkhill, T. Garnier, C. Churcher et al., Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence, Nature, vol.25, issue.6685, pp.537-544, 1998.
DOI : 10.1038/31159

M. Behr, M. Wilson, W. Gill, H. Salamon, G. Schoolnik et al., Comparative Genomics of BCG Vaccines by Whole-Genome DNA Microarray, Science, vol.284, issue.5419, pp.1520-1523, 1999.
DOI : 10.1126/science.284.5419.1520

R. Brosch, S. Gordon, C. Buchrieser, A. Pym, T. Garnier et al., Comparative genomics uncovers large tandem chromosomal duplications in Mycobacterium bovis BCG Pasteur, Yeast, vol.17, issue.17, pp.111-123, 2000.

T. Lowe and S. Eddy, tRNAscan-SE: A Program for Improved Detection of Transfer RNA Genes in Genomic Sequence, Nucleic Acids Research, vol.25, issue.5, pp.955-964, 1997.
DOI : 10.1093/nar/25.5.0955

M. Pedulla, M. Ford, J. Houtz, T. Karthikeyan, C. Wadsworth et al., Origins of Highly Mosaic Mycobacteriophage Genomes, Cell, vol.113, issue.2, pp.171-182, 2003.
DOI : 10.1016/S0092-8674(03)00233-2

K. Williams, Integration sites for genetic elements in prokaryotic tRNA and tmRNA genes: sublocation preference of integrase subfamilies, Nucleic Acids Research, vol.30, issue.4, pp.866-875, 2002.
DOI : 10.1093/nar/30.4.866

N. Winter, M. Lagranderie, J. Rauzier, J. Timm, C. Leclerc et al., Expression of heterologous genes in Mycobacterium bovis BCG: induction of a cellular response against HIV-1 Nef protein, Gene, vol.109, issue.1, pp.47-54, 1991.
DOI : 10.1016/0378-1119(91)90587-2