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[Management of DNA banks: ethical concerns]

Abstract : With the creation of DNA banks, short and long-term studies can be conducted on the DNA of many individuals using stored cells and tissues. These studies allow an analysis of the pathophysiological impact of genetics and help define individual markers predictive of risk. Genome analysis is thus an important advance in medical science, providing essential information for establishing appropriate measures to slow disease development, limit severity or improve safe recovery. The use of genetic results may however have an adverse effect in certain situations if the genetic information collected were deviated from its purely medical purpose under the influence of social, occupational or economic factors. The aim of our study was to analyse the ethical challenges linked to the implementation of DNA banks in France, particularly to see how to maintain the concept of individual protection in biomedical research within the patient-physician relationship in the current context of legal and administrative regulations in France. In this study, we discuss a set of criteria which should be systematically evaluated in information collection and consent procedures prior to blood or tissue procurement for DNA bank purposes.
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https://www.hal.inserm.fr/inserm-00118855
Contributor : Nathalie Duchange <>
Submitted on : Thursday, December 7, 2006 - 4:46:01 PM
Last modification on : Thursday, June 18, 2020 - 12:32:02 PM
Long-term archiving on: : Tuesday, April 6, 2010 - 7:21:39 PM

Identifiers

  • HAL Id : inserm-00118855, version 1
  • PUBMED : 10026722

Citation

Grégoire Moutel, Sandrine de Montgolfier, Karine Corviole, Martine Gaillard, Vincent Durlach, et al.. [Management of DNA banks: ethical concerns]. La Presse Médicale, Elsevier Masson, 1999, 28 (3), pp.135-9. ⟨inserm-00118855⟩

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