E. Puchelle, D. Gaillard, and D. Ploton, 32:34 REVUES SYNTHÈSE 1069 RÉFÉRENCES 1 Differential localization of the cystic fibrosis transmembrane conductance regulator in normal and cystic fibrosis airway epithelium, Am J Respir Cell Mol Biol, vol.1132, issue.7, pp.34-59, 1992.

E. Puchelle, S. De-bentzmann, and J. Zahm, Defense properties of airway surface liquid, Respiratory medicine, pp.194-204, 2003.

G. Lamblin, J. Aubert, and J. Perini, Human respiratory mucins, Eur Respir J, vol.5, pp.247-56, 1992.

R. Bals, D. Weiner, and J. Wilson, The innate immune system in cystic fibrosis lung disease, Journal of Clinical Investigation, vol.103, issue.3, pp.303-310, 1999.
DOI : 10.1172/JCI6277

W. Parks, Y. Lopez-boado, and C. Wilson, Matrilysin in Epithelial Repair and Defense, Chest, vol.120, issue.1, pp.36-41, 2001.
DOI : 10.1378/chest.120.1_suppl.S36

A. Mukherjee, G. Kundu, and G. Mantile-selvaggi, Uteroglobin: a novel cytokine?, Cellular and Molecular Life Sciences CMLS, vol.55, issue.5, pp.771-87, 1999.
DOI : 10.1007/s000180050331

I. Rahman and W. Macnee, Oxidative stress and regulation of glutathione in lung inflammation, European Respiratory Journal, vol.16, issue.3, pp.534-54, 2000.
DOI : 10.1034/j.1399-3003.2000.016003534.x

A. Marzesco, I. Dunia, and R. Pandjaitan, The Small GTPase Rab13 Regulates Assembly of Functional Tight Junctions in Epithelial Cells, Molecular Biology of the Cell, vol.13, issue.6, pp.1819-1850, 2002.
DOI : 10.1091/mbc.02-02-0029

C. Coraux, C. Kileztky, and M. Polette, -Adrenergic Receptor Agonist, American Journal of Respiratory Cell and Molecular Biology, vol.30, issue.5, pp.605-617, 2004.
DOI : 10.1165/rcmb.2003-0056OC
URL : https://hal.archives-ouvertes.fr/hal-00809316

J. Zabner, M. Winter, and K. Excoffon, Histamine alters E-cadherin cell adhesion to increase human airway epithelial permeability, Journal of Applied Physiology, vol.95, issue.1, pp.394-401, 2003.
DOI : 10.1152/japplphysiol.01134.2002

R. Wilson, T. Pitt, and G. Taylor, Pyocyanin and 1-hydroxyphenazine produced by Pseudomonas aeruginosa inhibit the beating of human respiratory cilia in vitro., Journal of Clinical Investigation, vol.79, issue.1, pp.221-230, 1987.
DOI : 10.1172/JCI112787

A. Niimi and K. Chung, Airway inflammation and remodelling changes in patients with chronic cough: do they tell us about the cause of cough?, Pulmonary Pharmacology & Therapeutics, vol.17, issue.6, pp.441-447, 2004.
DOI : 10.1016/j.pupt.2004.09.004

S. Man and W. Hulbert, Airway repair and adaptation to inhalation injury Pathophysiology and treatment of inhalation injuries Lung biology in health and disease, pp.1-47, 1988.

E. Puchelle and J. Zahm, Repair processes of the airway epithelium Airway and environnements : from injury to repair. Series : Lung biology in health and diseases, pp.1576-82, 1996.

A. Herard, J. Zahm, and D. Pierrot, Epithelial barrier integrity during in vitro wound repair of the airway epithelium., American Journal of Respiratory Cell and Molecular Biology, vol.15, issue.5, pp.624-656, 1996.
DOI : 10.1165/ajrcmb.15.5.8918369

D. Dorscheid, K. Wojcik, and K. Yule, Role of cell surface glycosylation in mediating repair of human airway epithelial cell monolayers, Am J Physiol Lung Cell Mol Physiol, vol.281, pp.982-92, 2001.

J. Zahm, H. Kaplan, and A. Herard, Cell migration and proliferation during the in vitro wound repair of the respiratory epithelium, Cell Motility and the Cytoskeleton, vol.3, issue.1, pp.33-43, 1997.
DOI : 10.1002/(SICI)1097-0169(1997)37:1<33::AID-CM4>3.0.CO;2-I

T. Gray, K. Guzman, and C. Davis, Mucociliary differentiation of serially passaged normal human tracheobronchial epithelial cells., American Journal of Respiratory Cell and Molecular Biology, vol.14, issue.1, pp.104-116, 1996.
DOI : 10.1165/ajrcmb.14.1.8534481

N. Castillon, J. Hinnrasky, and J. Zahm, Polarized Expression of Cystic Fibrosis Transmembrane Conductance Regulator and Associated Epithelial Proteins during the Regeneration of Human Airway Surface Epithelium in Three-Dimensional Culture, Laboratory Investigation, vol.11, issue.8, pp.989-98, 2002.
DOI : 10.1016/S0014-5793(98)00402-5
URL : https://hal.archives-ouvertes.fr/inserm-00149648

N. Ali, A. Edgar, and A. Samadikuchaksaraei, Derivation of Type II Alveolar Epithelial Cells from Murine Embryonic Stem Cells, Tissue Engineering, vol.8, issue.4, pp.541-50, 2002.
DOI : 10.1089/107632702760240463

C. Coraux, B. Nawrocki-raby, and J. Hinnrasky, Embryonic Stem Cells Generate Airway Epithelial Tissue, American Journal of Respiratory Cell and Molecular Biology, vol.32, issue.2, pp.87-92, 2005.
DOI : 10.1165/rcmb.2004-0079RC
URL : https://hal.archives-ouvertes.fr/inserm-00147182

E. Mcdowell, P. Becci, and W. Schurch, The respiratory epithelium. VII. Epidermoid metaplasia of hamster tracheal epithelium during regeneration following mechanical injury, J Natl Cancer Inst, vol.62, pp.995-1008, 1979.

A. Delplanque, C. Coraux, and R. Tirouvanziam, Epithelial stem cellmediated development of the human respiratory mucosa in SCID mice, J Cell Sci, vol.113, pp.767-78, 2000.

F. Dupuit, D. Gaillard, and J. Hinnrasky, Differentiated and functional human airway epithelium regeneration in tracheal xenografts, Am J Physiol Lung Cell Mol Physiol, vol.278, pp.165-76, 2000.

A. Herard, D. Pierrot, and J. Hinnrasky, Fibronectin and its alpha 5 beta 1-integrin receptor are involved in the wound-repair process of airway epithelium, Am J Physiol, vol.271, pp.726-759, 1996.

S. White, D. Dorscheid, and K. Rabe, Role of Very Late Adhesion Integrins in Mediating Repair of Human Airway Epithelial Cell Monolayers after Mechanical Injury, American Journal of Respiratory Cell and Molecular Biology, vol.20, issue.4, pp.787-96, 1999.
DOI : 10.1165/ajrcmb.20.4.3318

V. Proux-gillardeaux, J. Gavard, and T. Irinopoulou, Tetanus neurotoxin-mediated cleavage of cellubrevin impairs epithelial cell migration and integrin-dependent cell adhesion, Proceedings of the National Academy of Sciences, vol.302, issue.5642, pp.6362-6369, 2005.
DOI : 10.1126/science.1086652
URL : https://hal.archives-ouvertes.fr/hal-00007763

W. Hicks, . Jr, L. Sigurdson, and E. Gabalski, Does Cartilage Down-regulate Growth Factor Expression in Tracheal Epithelium?, Archives of Otolaryngology???Head & Neck Surgery, vol.125, issue.11, pp.1239-1282, 1999.
DOI : 10.1001/archotol.125.11.1239

A. Buisson, J. Zahm, and M. Polette, Gelatinase B is involved in the in vitro wound repair of human respiratory epithelium, Journal of Cellular Physiology, vol.4, issue.2, pp.413-439, 1996.
DOI : 10.1002/(SICI)1097-4652(199602)166:2<413::AID-JCP20>3.0.CO;2-A

C. Legrand, C. Gilles, and J. Zahm, Airway Epithelial Cell Migration Dynamics: MMP-9 Role in Cell???Extracellular Matrix Remodeling, The Journal of Cell Biology, vol.44, issue.Suppl., pp.517-546, 1999.
DOI : 10.1016/S0955-0674(89)80041-9

A. Buisson, C. Gilles, and M. Polette, Wound repair-induced expression of a stromelysins is associated with the acquisition of a mesenchymal phenotype in human respiratory epithelial cells, Lab Invest, vol.74, pp.658-69, 1996.

M. Polette, C. Gilles, and S. De-bentzmann, Association of fibroblastoid features with the invasive phenotype in human bronchial cancer cell lines, Clinical and Experimental Metastasis, vol.16, issue.2, pp.105-117, 1998.
DOI : 10.1023/A:1006572204497

S. Dunsmore, U. Saarialho-kere, and J. Roby, Matrilysin expression and function in airway epithelium., Journal of Clinical Investigation, vol.102, issue.7, pp.1321-1352, 1998.
DOI : 10.1172/JCI1516

J. Mcguire, Q. Li, and W. Parks, Matrilysin (Matrix Metalloproteinase-7) Mediates E-Cadherin Ectodomain Shedding in Injured Lung Epithelium, The American Journal of Pathology, vol.162, issue.6, pp.1831-1874, 2003.
DOI : 10.1016/S0002-9440(10)64318-0

L. Sigurdson, T. Sen, and L. Hall, Possible Impedance of Luminal Reepithelialization by Tracheal Cartilage Metalloproteinases, Archives of Otolaryngology???Head & Neck Surgery, vol.129, issue.2, pp.197-200, 2003.
DOI : 10.1001/archotol.129.2.197

C. Coraux, C. Martinella-catusse, and B. Nawrocki-raby, Differential expression of matrix metalloproteinases and interleukin-8 during regeneration of human airway epitheliumin vivo, The Journal of Pathology, vol.151, issue.2, pp.160-169, 2005.
DOI : 10.1002/path.1757

S. Puddicombe, R. Polosa, and A. Richter, Involvement of the epidermal growth factor receptor in epithelial repair in asthma, The FASEB Journal, vol.14, issue.10, pp.1362-74, 2000.
DOI : 10.1096/fj.14.10.1362

R. Barrow, C. Wang, and M. Evans, Growth factors accelerate epithelial repair in sheep trachea, Lung, vol.141, issue.3, pp.335-379, 1993.
DOI : 10.1007/BF00165699

J. Zahm, C. Debordeaux, and B. Raby, Motogenic effect of recombinant HGF on airway epithelial cells during the in vitro wound repair of the respiratory epithelium, Journal of Cellular Physiology, vol.1, issue.3, pp.447-53, 2000.
DOI : 10.1002/1097-4652(200012)185:3<447::AID-JCP16>3.0.CO;2-D

C. Waters and U. Savla, Keratinocyte growth factor accelerates wound closure in airway epithelium during cyclic mechanical strain, Journal of Cellular Physiology, vol.37, issue.3, pp.424-456, 1999.
DOI : 10.1002/(SICI)1097-4652(199912)181:3<424::AID-JCP6>3.0.CO;2-Z

W. Hicks, . Jr, L. Hall, and D. Tristram, Interleukin-1 Facilitates Airway Epithelial Migration in Response to Injury, The Laryngoscope, vol.279, issue.2, pp.243-250, 2003.
DOI : 10.1097/00005537-200302000-00009

M. Lundien, K. Mohammed, and N. Nasreen, Induction of MCP-1 expression in airway epithelial cells : role of CCR2 receptor in airway epithelial injury, Journal of Clinical Immunology, vol.22, issue.3, pp.144-52, 2002.
DOI : 10.1023/A:1015420029430

C. Chwieralski, I. Schnurra, and L. Thim, Epidermal Growth Factor and Trefoil Factor Family 2 Synergistically Trigger Chemotaxis on BEAS-2B Cells via Different Signaling Cascades, American Journal of Respiratory Cell and Molecular Biology, vol.31, issue.5, pp.528-565, 2004.
DOI : 10.1165/rcmb.2003-0433OC

P. Vermeer, L. Einwalter, and T. Moninger, Segregation of receptor and ligand regulates activation of epithelial growth factor receptor, Nature, vol.422, issue.6929, pp.322-328, 2003.
DOI : 10.1038/nature01440

B. Shen, R. Panos, and K. Hansen-guzman, Hepatocyte growth factor stimulates the differentiation of human tracheal epithelia in vitro, Am J Physiol, vol.272, pp.1115-1135, 1997.

A. Clark, S. Randell, and P. Nettesheim, Regulation of ciliated cell differentiation in cultures of rat tracheal epithelial cells., American Journal of Respiratory Cell and Molecular Biology, vol.12, issue.3, pp.329-367, 1995.
DOI : 10.1165/ajrcmb.12.3.7873199

P. Burgel and J. Nadel, Roles of epidermal growth factor receptor activation in epithelial cell repair and mucin production in airway epithelium, Thorax, vol.59, issue.11, pp.992-998, 2004.
DOI : 10.1136/thx.2003.018879

J. Laoukili, E. Perret, and T. Willems, IL-13 alters mucociliary differentiation and ciliary beating of human respiratory epithelial cells, Journal of Clinical Investigation, vol.108, issue.12, pp.1817-1841, 2001.
DOI : 10.1172/JCI200113557

E. Blatt, X. Yan, and M. Wuerffel, Forkhead Transcription Factor HFH-4 Expression Is Temporally Related to Ciliogenesis, American Journal of Respiratory Cell and Molecular Biology, vol.21, issue.2, pp.168-76, 1999.
DOI : 10.1165/ajrcmb.21.2.3691

Y. You, T. Huang, and E. Richer, Role of f-box factor foxj1 in differentiation of ciliated airway epithelial cells, AJP: Lung Cellular and Molecular Physiology, vol.286, issue.4, pp.650-657, 2004.
DOI : 10.1152/ajplung.00170.2003

L. Ostrowski, K. Andrews, and P. Potdar, Cloning and Characterization of KPL2, a Novel Gene Induced during Ciliogenesis of Tracheal Epithelial Cells, American Journal of Respiratory Cell and Molecular Biology, vol.20, issue.4, pp.675-83, 1999.
DOI : 10.1165/ajrcmb.20.4.3496

C. Bingle and J. Gitlin, Identification of hepatocyte nuclear factor-3 binding sites in the Clara cell secretory protein gene, Biochemical Journal, vol.295, issue.1, pp.227-259, 1993.
DOI : 10.1042/bj2950227